Advances in Knowledge Discovery and Data Mining
28th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2024, Taipei, Taiwan, May 7–10, 2024, Proceedings, Part V
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Open AccessSynthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLSBK) antibiotics are unable to counter the growing challenge of antibiotic resistance that is conferred by the constitutive methylation of rRNA base ...
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Comparative analysis of the performance of hepatobiliary agents in depicting MRI features of microvascular infiltration in hepatocellular carcinoma
To compare the ability to depict MRI features of hepatobiliary agents in microvascular infiltration (MVI) of hepatocellular carcinoma (HCC) during different stages of dynamic enhancement MRI.
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Open AccessVirtual reality-based simulation learning on geriatric oral health care for nursing students: a pilot study
There is a great need for training and education in the nursing curriculum to improve nurses’ knowledge and skills to provide oral health care.
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Open AccessMild hyperthermia enhanced synergistic uric acid degradation and multiple ROS elimination for an effective acute gout therapy
Acute gouty is caused by the excessive accumulation of Monosodium Urate (MSU) crystals within various parts of the body, which leads to a deterioration of the local microenvironment. This degradation is marked...
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Air permeability variation of compacted loess: effects of soil basic properties and dry-wet cycles
Loess, featured by its low permeability and cost-effectiveness, has become an increasingly popular material for landfill cover systems. However, the occurrence of cracks in loess caused by rainfall and evapora...
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Open AccessA novel long non-coding RNA MIR4500HG003 promotes tumor metastasis through miR-483-3p-MMP9 axis in triple-negative breast cancer
Breast cancer (BC) is the most common cancer and the leading cause of cancer-related deaths in women worldwide. The 5-year survival rate is over 90% in BC patients, but once BC cells metastasis into distal org...
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Open AccessIntestinal dual-specificity phosphatase 6 regulates the cold-induced gut microbiota remodeling to promote white adipose browning
Gut microbiota rearrangement induced by cold temperature is crucial for browning in murine white adipose tissue. This study provides evidence that DUSP6, a host factor, plays a critical role in regulating cold...
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Article
Open AccessGenetic drivers of heterogeneity in type 2 diabetes pathophysiology
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic c...
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Paraptosis: a non-classical paradigm of cell death for cancer therapy
Due to the sustained proliferative potential of cancer cells, inducing cell death is a potential strategy for cancer therapy. Paraptosis is a mode of cell death characterized by endoplasmic reticulum (ER) and/...
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Structural evolution, interlayer coupling, band-gap, and optical properties of non-layered SiCNSs
Silicon carbide nanosheets (SiCNRs) have a broad application prospect in the new generation of micro/nanophotonic devices. Based on the previous study of layered SiCNSs (FL-SiCNSs), the first-principles calcul...
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Book and Conference Proceedings
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Book and Conference Proceedings
Advances in Knowledge Discovery and Data Mining
28th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2024, Taipei, Taiwan, May 7–10, 2024, Proceedings, Part III
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Book and Conference Proceedings
Genetic and Evolutionary Computing
Proceedings of the Fifteenth International Conference on Genetic and Evolutionary Computing (Volume II), October 6-8, 2023, Kaohsiung, Taiwan
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Book and Conference Proceedings
Advances in Knowledge Discovery and Data Mining
28th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2024, Taipei, Taiwan, May 7–10, 2024, Proceedings, Part I
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Book and Conference Proceedings
Advances in Knowledge Discovery and Data Mining
28th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2024, Taipei, Taiwan, May 7–10, 2024, Proceedings, Part II
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Book and Conference Proceedings
Advances in Knowledge Discovery and Data Mining
28th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2024, Taipei, Taiwan, May 7–10, 2024, Proceedings, Part IV
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Book and Conference Proceedings
Advances in Knowledge Discovery and Data Mining
28th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2024, Taipei, Taiwan, May 7–10, 2024, Proceedings, Part VI
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Article
Diffusion and structural MRI as potential biomarkers in people with Parkinson’s disease and cognitive impairment
To explore the neuroimage change in Parkinson’s disease (PD) patients with cognitive impairments, this study investigated the correlation between plasma biomarkers and morphological brain changes in patients w...
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Open AccessA novel mucosal bivalent vaccine of EV-A71/EV-D68 adjuvanted with polysaccharides from Ganoderma lucidum protects mice against EV-A71 and EV-D68 lethal challenge
Human enteroviruses A71 (EV-A71) and D68 (EV-D68) are the suspected causative agents of hand-foot-and-mouth disease, aseptic meningitis, encephalitis, acute flaccid myelitis, and acute flaccid paralysis in chi...
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Open AccessEstimating genome-wide DNA methylation heterogeneity with methylation patterns
In a heterogeneous population of cells, individual cells can behave differently and respond variably to the environment. This cellular diversity can be assessed by measuring DNA methylation patterns. The loci ...
