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  1. Article

    Open Access

    Prognostic value of the Naples prognostic score in patients with intrahepatic cholangiocarcinoma after hepatectomy

    The Naples Prognostic Score (NPS), integrating inflammatory and nutritional biomarkers, has been reported to be associated with the prognosis of various malignancies, but there is no report on intrahepatic cho...

    Cheng-Fei Du, Zhen-Yu Gao, Zhu-Ding Xu, Zheng-Kang Fang, Zi-Chen Yu in BMC Cancer (2024)

  2. Article

    Open Access

    Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers

    Dysregulation of enhancer transcription occurs in multiple cancers. Enhancer RNAs (eRNAs) are transcribed products from enhancers that play critical roles in transcriptional control. Characterizing the genetic...

    Yi-Min Cai, Ze-Qun Lu, Bin Li, **-Yu Huang, Ming Zhang in Military Medical Research (2024)

  3. No Access

    Article

    Regulatory effect of Yinchenhao decoction on bile acid metabolism to improve the inflammatory microenvironment of hepatocellular carcinoma in mice

    Hepatocellular carcinoma (HCC) is a malignant tumor with extremely high mortality. The tumor microenvironment is the “soil” of its occurrence and development, and the inflammatory microenvironment is an import...

    Jian Shi, Lin Zhu, Bang-Yi Tang, Wan-Qing Yang in Journal of Natural Medicines (2024)

  4. Article

    Open Access

    Association between serum vitamin E and bacterial vaginitis in women: a cross-sectional study

    Bacterial vaginitis (BV) is a common vaginal disease. Vitamin E has been shown to reduce BV by enhancing immune function, but no studies have analyzed the relationship between vitamin E and BV at different BMI...

    En-Hui Liu, Wan-Zhe Liao, Hao-Kai Chen, **ao-Ye Huang, Rui-Xuan Li in BMC Women's Health (2024)

  5. Article

    Open Access

    Structural basis and synergism of ATP and Na+ activation in bacterial K+ uptake system KtrAB

    The K+ uptake system KtrAB is essential for bacterial survival in low K+ environments. The activity of KtrAB is regulated by nucleotides and Na+. Previous studies proposed a putative gating mechanism of KtrB regu...

    Wesley Tien Chiang, Yao-Kai Chang, Wei-Han Hui, Shu-Wei Chang in Nature Communications (2024)

  6. Article

    Open Access

    Refraction and topographic risk factors for early myopic regression after small-incision lenticule extraction surgery

    We sought to evaluate the topographic risk factors for early myopic regression after small-incision lenticule extraction (SMILE). A retrospective case‒control study was conducted, and individuals who underwent...

    Chia-Yi Lee, Yu-Ting Jeng, Chen-Cheng Chao, Ie-Bin Lian in Scientific Reports (2024)

  7. Article

    Open Access

    Topographic and surgical risk factors for high postoperative residual astigmatism after small incision lenticule extraction in patients with different degrees of myopia: a retrospective cohort study

    To evaluate the possible topographic and surgical risk factors for high postoperative residual astigmatism in patients who undergo small-incision lenticule extraction (SMILE) surgery and have different myopia ...

    Chia-Yi Lee, Jen-Hsiang Shen, Chen-Cheng Chao, Ie-Bin Lian in BMC Ophthalmology (2024)

  8. Article

    Open Access

    TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts

    Pathologic scars, including keloids and hypertrophic scars, represent a common form of exaggerated cutaneous scarring that is difficult to prevent or treat effectively. Additionally, the pathobiology of pathol...

    Yi-Kai Hong, Yu-Chen Lin, Tsung-Lin Cheng, Chao-Han Lai in Journal of Biomedical Science (2024)

  9. No Access

    Article

    Roadmap for rechargeable batteries: present and beyond

    Rechargeable batteries currently hold the largest share of the electrochemical energy storage market, and they play a major role in the sustainable energy transition and industrial decarbonization to respond t...

    Sen **n, Xu Zhang, Lin Wang, Haijun Yu, **n Chang, Yu-Ming Zhao in Science China Chemistry (2024)

  10. No Access

    Chapter and Conference Paper

    Real-Time Automated Body Condition Scoring of Dairy Cows

    Traditional management and farming of dairy cows have relied primarily on human labor and experience. However, this approach has limitations such as the lack of real-time monitoring and predictive capabilities...

    Jia-Hong Lai, Fay Huang, Yi-Hsin Yeh, Kuo-Hua Lee in Image and Video Technology (2024)

  11. Article

    Open Access

    The association between homocysteine and bacterial vaginosis: results from NHANES 2001–2004

    Although no study has directly shown the relationship between bacterial vaginosis (BV) and homocysteine (HCY), we still found some association between these two through extensive literature and data analysis. ...

    **g Luo, Tong Chen, Yue Chen, Ze-Min Huang, **u-Juan Li in Scientific Reports (2023)

  12. No Access

    Article

    Identifying the Interaction Between Tuberculosis and SARS-CoV-2 Infections via Bioinformatics Analysis and Machine Learning

    The number of patients with COVID-19 caused by severe acute respiratory syndrome coronavirus 2 is still increasing. In the case of COVID-19 and tuberculosis (TB), the presence of one disease affects the infect...

    Ze-Min Huang, Jia-Qi Kang, Pei-Zhen Chen, Lin-Fen Deng, Jia-**n Li in Biochemical Genetics (2023)

  13. Article

    Open Access

    Loss of fragile WWOX gene leads to senescence escape and genome instability

    Induction of DNA damage response (DDR) to ensure accurate duplication of genetic information is crucial for maintaining genome integrity during DNA replication. Cellular senescence is a DDR mechanism that prev...

    Hui-Ching Cheng, Po-Hsien Huang, Feng-Jie Lai in Cellular and Molecular Life Sciences (2023)

  14. No Access

    Article

    Identifying the Leading Global Contributors to Scholarship in Religion Journals: A Bibliometric Study

    This study identified the 100 most impactful global contributors to religion journals and mapped their respective disciplinary affiliations. To conduct this investigation, we performed a secondary data analysi...

    David R. Hodge, Patricia R. Turner, Chao-Kai Huang in Journal of Religion and Health (2023)

  15. Article

    Open Access

    Coffee consumption and periodontitis: a Mendelian Randomization study

    Coffee is one of the most consumed beverages in the world, coffee consumption has been growing in the United States over the past 20 years. Periodontitis is defined by the pathologic loss of the periodontal li...

    Wan-Zhe Liao, Zhi-Yi Zhou, Zi-Kai Lin, Shuo-Jia **e, Ya-Fang Zheng in Genes & Nutrition (2023)

  16. Article

    Open Access

    Negative associations between folate and bacterial vaginosis in the NHANES 2001 to 2004

    Bacterial vaginosis (BV) is one of the most common infections among women of reproductive age and accounts for 15–50% of infections globally. The role played by folate in the pathogenesis and progression of BV...

    Ting-Ting Cui, **g Luo, Rui-Lan Deng, Yun-Ting Yang, Ya-Wen Yin in BMC Infectious Diseases (2023)

  17. Article

    Open Access

    Discrimination of Baphicacanthis Cusiae Rhizoma et radix and its adulterant species and establishment of an assay method for quality control

    Baphicacanthis Cusiae Rhizoma et Radix, commonly known as Nan-Ban-Lan-Gen (NBLG), is an essential traditional Chinese medicine that possesses diverse bioactivities, particularly noteworthy for its antiviral prope...

    Yue Li, Qiong-** Yu, Lee-Fong Yau, Guo-Kai Huang, **g-Guang Lu in Chinese Medicine (2023)

  18. Article

    Biomarkers of aging

    Aging biomarkers are a combination of biological parameters to (i) assess age-related changes, (ii) track the physiological aging process, and (iii) predict the transition into a pathological status. Although ...

    Hainan Bao, Jiani Cao, Mengting Chen, Min Chen, Wei Chen in Science China Life Sciences (2023)

  19. No Access

    Article

    High-rate quantum key distribution exceeding 110 Mb s–1

    Quantum key distribution (QKD) can provide fundamentally proven secure communication. Towards application, the secret key rate (SKR) is a key figure of merit for any QKD system. The SKR has so far been limited...

    Wei Li, Likang Zhang, Hao Tan, Yichen Lu, Sheng-Kai Liao, Jia Huang in Nature Photonics (2023)

  20. No Access

    Article

    BCI-based hit-loop agent for human and AI robot co-learning with AIoT application

    In this paper, we propose a brain–computer interface (BCI)-based Human-in-the-Loop (Hit-Loop) agent for human and artificial intelligence (AI) colearning in music listening and appreciation with an Artificial Int...

    Chang-Shing Lee, Mei-Hui Wang, Wen-Kai Kuan in Journal of Ambient Intelligence and Humani… (2023)

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