-
Article
PAF-induced bowel necrosis
Ischemic bowel necrosis in the rat is produced by injecting platelet-activating factor (PAF) intravenously. Since intestinal hypoperfusion is observed after PAF injection, we hypothesize that mesenteric vasoco...
-
Article
Serum α-l-fucosidase
Forty-nine liver disease patients (7 chronic persistent hepatitis, CPH; 10 chronic active hepatitis, CAH; 13 liver cirrhosis, LC; 9 primary hepatocellular carcinoma, PHC, without LC; and 10 PHC with associated...
-
Article
Effect of small doses of somatostatin analog, octreotide, on gallbladder contractility in normal Chinese adults
The acute effects of single different doses of the somatostatin analog octreotide on the contractility of the gallbladder stimulated by fatty meal were studied in six healthy Chinese volunteers. Gallbladder co...
-
Article
Relationship between tissue calcium content and duodenal ulcer in the rat
Since the effect of cellular calcium on cell injury has been in question, this study focused on the relationship between tissue calcium content and cysteamine-induced duodenal ulcer. Rats treated with cysteami...
-
Article
Enhanced patency of venous dacron grafts by endothelial cell sodding
The effect of microvessel endothelial cell (EC) sodding on the patency of Dacron grafts interposed in canine inferior vena cava was studied. EC were harvested enzymatically from canine omentum and isolated by ...
-
Article
Whole Endometrial Fragments Form Characteristics of In Vivo Endometriosis in a Mesothelial Cell Co-Culture System: An In Vitro Model for the Study of the Histogenesis of Endometriosis
We have previously reported on the effects of tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1) on the adhesion of human endometrial stromal cells to peritoneal mesothelial cells in vitro. The relevance...
-
Chapter and Conference Paper
Transcriptional Regulation of IL-1ß and IL-6 by TNF-α in Asbestosis is Mediated by NF-IL6-like Motifs
Asbestosis is an inflammatory and fibrotic interstitial lung disease characterized by a lower respiratory tract alveolitis and bronchiolitis with increased macrophages, lymphocytes, and neutrophils. The alveol...
-
Article
Effect of octreotide on dynamic excretion of bile in Chinese acromegalic patients assessed by [99mTc]EHIDA hepatobiliary scan
We used [99mTc]EHIDA hepatobiliary scintigraphy to determine whether both hepatic bile secretion and gallbladder contractility are suppressed in acromegalic patients receiving long-term treatment with the somatos...
-
Article
Intrahepatic mononuclear cell populations and MHC antigen expression in patients with chronic hepatitis B: Effect of interferon-α
Twenty-four subjects with chronic HCV infection were treated with IFN for six months. Liver biopsies were obtained before and after therapy. The number of mononuclear cells staining for CD3, CD4, CD8, 3G8, and...
-
Article
Inhibition of calcium-dependent nitric oxide synthase causes ileitis and leukocytosis in guinea pigs
As nitric oxide reduces gut epithelial permeability, we designed a study to determine if chronic nitric oxide synthase inhibition predisposes the gut to inflammation. Nitric oxide synthase (NOS) inhibitors wer...
-
Article
Loss of blood group antigen a in non-small cell lung cancer
Background: Many human tumor cells display alterations in blood group antigen expression, and the loss of antigen A expression by non-small cell lung cancer (NSCLC) in blood group A patients has recently been as...
-
Article
Beta Adrenoceptor Blockade Mimics Effects of Stress on Motor Activity in Mice
Reduced central noradrenergic function has been implicated as a factor in reduced behavioral activity after stress. The present studies examined the role of reduced beta adrenergic neurotransmission in mediati...
-
Article
Aggravation of gastric mucosal lesions in rat stomach by tobacco cigarette smoke
In the model of gastric mucosal injury induced by 2 mol/liter hypertonic saline in rats, we tested the hypothesis that tobacco cigarette smoke aggravates gastric mucosal lesions by inhibition of injury-induced...
-
Article
Fractionated irradiation alters enteric neuroendocrine products
Radiation profoundly alters the contractile activity of the small intestine and colon. We hypothesized that some motor changes of the gut might be secondary to impaired neural input to smooth muscle or abnorma...
-
Article
Inhibition of endogenous nitric oxide reduces basal mesenteric vascular tone but does not alter intraduodenal hydrochloric acid-induced intestinal hyperemia in rats
There are conflicting reports on the role of endogenous nitric oxide (NO) in the regulation of basal intestinal blood flow. The effect of inhibition of NO on intraduodenal hydrochloric acid (HCl) induced intes...
-
Article
Cyclic Expression of Endothelial Nitric Oxide Synthase mRNA in the Epithelial Glands of Human Endometrium
Nitric oxide synthase (NOS), responsible for the synthesis of nitric oxide (NO), is the key enzyme that regulates the NO-mediated biologic functions in various types of tissue. We believed that NO may be invol...
-
Article
Intact 5-HT2A Receptor Exons and the Adjoining Intron Regions in Schizophrenia
Genes that regulate serotonergic (5-HT) systems may underlie the etiology of schizophrenia. In this study the gene encoding the 5-HT2A receptor in schizophrenics and healthy controls was examined. First, we seque...
-
Article
Sentinel node biopsy in breast cancer
Background: Sentinel lymph node biopsy (SNB) in breast cancer may be used in place of axillary lymph node dissection (ALND) if SNB accurately stages the axilla. This study assessed the success and accuracy of ax...
-
Article
Accuracy of Pathologic Techniques for the Diagnosis of Metastatic Melanoma in Sentinel Lymph Nodes
Background: Sentinel lymph node (SLN) biopsy can accurately predict the presence of metastatic melanoma (MM) and has been used to identify patients with occult metastases. We present an analysis of the sensitivit...
-
Article
Estrogen Decreases Prostaglandin H Synthase Products From Endothelial Cells
Because we showed recently that estrogen replacement prevents prostaglandin H synthase (PGHS)—dependent vasoconstriction in rats, the aim of this study was to determine how estradiol affects production of PGHS...
