55 Result(s)
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Article
Beta Adrenoceptor Blockade Mimics Effects of Stress on Motor Activity in Mice
Reduced central noradrenergic function has been implicated as a factor in reduced behavioral activity after stress. The present studies examined the role of reduced beta adrenergic neurotransmission in mediati...
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Article
Intact 5-HT2A Receptor Exons and the Adjoining Intron Regions in Schizophrenia
Genes that regulate serotonergic (5-HT) systems may underlie the etiology of schizophrenia. In this study the gene encoding the 5-HT2A receptor in schizophrenics and healthy controls was examined. First, we seque...
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Article
Placental Pathology Casebook: Serpentine Aneurysms of the Placenta with Fetal Consequences
Two cases of placental surface vessel aneurysms are presented. One case was associated with severe fetal intrauterine growth restriction and fetal thrombocytopenia. The other case was associated with “molar tr...
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Article
Synergistic Effects of Olanzapine and Other Antipsychotic Agents in Combination with Fluoxetine on Norepinephrine and Dopamine Release in Rat Prefrontal Cortex
To understand the mechanism of the clinical efficacy of olanzapine and fluoxetine combination therapy for treatment-resistant depression (TRD), we studied the effects of olanzapine and other antipsychotics in ...
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Article
Role of Dopamine D4 Receptors in Motor Hyperactivity Induced by Neonatal 6-Hydroxydopamine Lesions in Rats
The role of dopamine D4 receptors in behavioral hyperactivity was investigated by assessing D4 receptor expression in brain regions and behavioral effects of D4 receptor-selective ligands in juvenile rats with ne...
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Article
Stem Cells in Neurodevelopment and Plasticity
The processes of stem cell proliferation and differentiation during embryogenesis are governed by transcription factors that regulate the regional differentiation of the central nervous system (CNS). Do neural...
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Article
Plasticity of Dopamine D4 Receptors in Rat Forebrain: Temporal Association with Motor Hyperactivity Following Neonatal 6-Hydroxydopamine Lesioning
Genetic studies suggest that dopamine D4 receptor polymorphism is associated with attention deficit hyperactivity disorder (ADHD). We recently reported that motor hyperactivity in juvenile male rats with neonatal...
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Article
Antidepressant-like Profile and Reduced Sensitivity to Rolipram in Mice Deficient in the PDE4D Phosphodiesterase Enzyme
Pharmacological inhibition of type 4 cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase (PDE4) produces antidepressant-like effects in animals; however, it is not known which of the four PDE4 sub...
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Article
Fetal Laryngeal Stenosis/Atresia and Congenital High Airway Obstructive Syndrome (CHAOS): A Case Report
Congenital high airway obstructive syndrome (CHAOS) is a rare but fatal disease with predictably characteristic features including stenotic or atretic upper airway, hyperplastic lungs, elevated diaphragm, mass...
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Article
Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension (26 years clinical observation)
The surgical treatment methods for cirrhosis patients complicated with portal hypertension are complicated. In this study, we evaluated the effectiveness of a new treatment strategy: splenic auto-transplantati...
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Article
Construction of 6HRE-GFAP-Baxα system specific for glioma gene therapy
The aim of this paper is to construct a specific and high-performance gene therapy system for glioma. We constructed a combined promoter 6HRE-GFAP (Hypoxia Responsive Element, Glial Fibrillary Acidic Protein) ...
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Article
Surgical treatment of hepatocellular carcinoma with cirrhotic esophageal varices and hypersplenism: a 184 case report
In treating hepatocellular carcinoma (HCC) patients with advanced cirrhosis, one of the most difficult problems is concomitant esophageal varices and hypersplenism. Whether these conditions should be treated s...
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Article
Effect of end-to-end invagination pancreaticojejunostomy with circle discontinuous U suture in pancreatic surgery
The aim of this paper is to summarize the methods of pancreaticojejunostomy in the pancreatic operation and to study the safety and feasibility of a new operative method called end-to-end invagination pancreat...
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Article
Experimental study on the establishment and maintenance of brain death model with pigs
It remains controversial that after the transplantation of using grafts from brain-dead donors, organs injury and rejection can influence the effects of transplantation. This study sought to explore methods of...
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Article
Ultramicrostructure and clinical implications of satellite foci in front of the head of pterygium
In our previous studies, grey satellite foci were found in the front of heads of pterygia. This research was designed to investigate the ultramicrostructure and clinical implications of these satellite foci. T...
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Article
Emergency adult living donor right lobe liver transplantation for fulminant hepatic failure
Fulminant hepatitis is fatal in most cases and timely liver transplantation is the only effective treatment. This study evaluates the survival outcomes of patients who underwent living-donor liver transplantat...
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Article
Mutation analysis of KCNQ1, KCNH2, SCN5A, KCNE1 and KCNE2 genes in Chinese patients with long QT syndrome
Long QT syndrome (LQTS) is the prototype of the cardiac ion channelopathies, which cause syncope and sudden death. Inherited LQTS is represented by the autosomal dominant Romano-ward syndrome (RWS), which is n...
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Article
Fractures of the Distal Tibia Treated with Polyaxial Locking Plating
We evaluated the healing rate, complications, and functional outcomes in 32 adult patients with very short metaphyseal fragments in fractures of the distal tibia treated with a polyaxial locking system. The av...
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Article
Felodipine downregulates serum interleukin-18 levels in rats with fructose-induced metabolic syndrome
Objective: Human studies suggest that calcium-channel blockers have cardiovascular protection besides reducing blood pressure, and interleukin-18 (IL-18) levels which are elevated in obes...
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Article
Predictors of Prognosis for Elderly Patients with Poststroke Hemiplegia Experiencing Hip Fractures
Hip fracture is an important cause of mortality and disability in elderly patients, particularly in those with poststroke hemiplegia, but little information is available regarding differences of general charac...
