65 Result(s)

Article

Individual cerebellar metabolic connectome in patients with MTLE and NTLE associated with surgical prognosis

This study aimed to comprehensively explore the different metabolic connectivity topological changes in MTLE and NTLE, as well as their association with surgical outcomes.

Yongxiang Tang, Haoyue Zhu, Ling **ao… in European Journal of Nuclear Medicine and M… (2024)

Article

Platelet-derived growth factor receptor β-targeted positron emission tomography imaging for the noninvasive monitoring of liver fibrosis

Noninvasive quantifying activated hepatic stellate cells (aHSCs) by molecular imaging is helpful for assessing disease progression and therapeutic responses of liver fibrosis. Our purpose is to develop platele...

Zhao Li, Hao Yang, **n Li, Tianshan She… in European Journal of Nuclear Medicine and M… (2024)

Article

Application of Northern Goshawk Back-Propagation Artificial Neural Network in the Prediction of Monohydroxycarbazepine Concentration in Patients with Epilepsy

A northern goshawk back-propagation artificial neural network (NGO-BPANN) model was established to predict monohydroxycarbazepine (MHD) concentration in patients with epilepsy.

Yichao Xu, Rong Shao, Mingdong Yang, Meng Chen, Junjun Xu… in Advances in Therapy (2024)

Article

Simultaneous high-resolution whole-brain MR spectroscopy and [¹⁸F]FDG PET for temporal lobe epilepsy

Precise lateralizing the epileptogenic zone in patients with drug-resistant mesial temporal lobe epilepsy (mTLE) remains challenging, particularly when routine MRI scans are inconclusive (MRI-negative). This s...

Hui Huang, Miao Zhang, Yibo Zhao, Yudu Li… in European Journal of Nuclear Medicine and M… (2024)

Article

[⁶⁸Ga]Ga‑LNC1007 PET/CT in the evaluation of renal cell carcinoma: comparison with 2-[¹⁸F]FDG/[⁶⁸Ga]Ga-PSMA PET/CT

To compare the potential efficiency of [⁶⁸Ga]Ga-LNC1007 with 2-[¹⁸F]FDG/[⁶⁸Ga]Ga-PSMA PET/CT for detecting renal cell carcinoma (RCC) and to explore parameters derived from [⁶⁸Ga]Ga-LNC1007 PET/CT for discriminat...

Rong Lin, Chao Wang, Shaohao Chen… in European Journal of Nuclear Medicine and M… (2024)

Article

Differences in whole-brain metabolism are associated with the expression of genes related to neurovascular unit integrity and synaptic plasticity in temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is a common, polygenic epilepsy syndrome that involves glucose hypometabolism in the epileptogenic zone. However, the transcriptional and cellular signatures underlying the metabol...

Ling **ao, Yongxiang Tang, Chijun Deng… in European Journal of Nuclear Medicine and M… (2023)

Article

Robust deep learning-based PET prognostic imaging biomarker for DLBCL patients: a multicenter study

To develop and independently externally validate robust prognostic imaging biomarkers distilled from PET images using deep learning techniques for precise survival prediction in patients with diffuse large B c...

Chong Jiang, Chunjun Qian, Zekun Jiang… in European Journal of Nuclear Medicine and M… (2023)

Article

Association of protein distribution and gene expression revealed by positron emission tomography and postmortem gene expression in the dopaminergic system of the human brain

The topological distribution of dopamine-related proteins is determined by gene transcription and subsequent regulations. Recent research strategies integrating positron emission tomography with a transcriptom...

Yasuharu Yamamoto, Keisuke Takahata… in European Journal of Nuclear Medicine and M… (2023)

Article

PET imaging with FAPI-ligands for non-cirrhotic hepatocellular carcinoma

Zhenghong Lee, Zheng-Rong Lu, Sandra Sexton… in European Journal of Nuclear Medicine and M… (2023)

Article

Genetic Evidence Supporting Causal Roles of mTOR-Dependent Proteins in Rheumatic Fever: A Two-Sample Randomized Mendelian Study

The expression of signaling molecules downstream of the mammalian target of rapamycin (mTOR) is dysregulated in patients with rheumatic fever (RF), but the causality of mTOR on RF remains unknown. This study a...

Yan-Fei Mu, Qian Wang, **g-** Hu, Qi Wang, Yao-Chen Zhang… in Advances in Therapy (2023)

Article

Cost–Utility Analysis of Darolutamide Combined with Androgen Deprivation Therapy for Patients with High-Risk Non-Metastatic Castration-Resistant Prostate Cancer in China

The increasing incidence of prostate cancer (PC) in China leads to a significant disease burden. Although three novel androgen inhibitors (darolutamide, apalutamide, and enzalutamide) have been approved for pa...

Jian Ming, Yuxia Wu, Rong Han, **ng Xu, Reg Waldeck, Shanlian Hu in Advances in Therapy (2023)

Article

Chlorin e6-loaded goat milk-derived extracellular vesicles for Cerenkov luminescence-induced photodynamic therapy

Photodynamic therapy (PDT) is a promising cancer treatment strategy with rapid progress in preclinical and clinical settings. However, the limitations in penetration of external light and precise delivery of phot...

Rong Guo, Dawei Jiang, Yongkang Gai… in European Journal of Nuclear Medicine and M… (2023)

Article

Theranostic application of ⁶⁴Cu/¹⁷⁷Lu-labeled anti-Trop2 monoclonal antibody in pancreatic cancer tumor models

Pancreatic cancer is a malignant tumor with a high degree of malignancy, strong heterogeneity, and high lethality. Trop2 is a transmembrane glycoprotein associated with the occurrence, development, and poor pr...

Cuicui Li, Jun Liu, Xu Yang, Qi Yang… in European Journal of Nuclear Medicine and M… (2022)

Article

A quantitative in vivo imaging platform for tracking pathological tau depositions and resultant neuronal death in a mouse model

Depositions of tau fibrils are implicated in diverse neurodegenerative disorders, including Alzheimer’s disease, and precise assessments of tau pathologies and their impacts on neuronal survival are crucial fo...

Taeko Kimura, Maiko Ono, Chie Seki… in European Journal of Nuclear Medicine and M… (2022)

Article

Novel recombinant human thyroid-stimulating hormone in aiding postoperative assessment of patients with differentiated thyroid cancer—phase I/II study

Thyroid hormone withdrawal (THW) inevitably induced hypothyroidism in patients with differentiated thyroid cancer (DTC), and we aimed to evaluate the safety and efficacy of a novel recombinant human thyroid-st...

Yan-Song Lin, Hui Yang, **ao-Yi Li… in European Journal of Nuclear Medicine and M… (2022)

Article

Levels of Peripheral Th17 Cells and Th17-Related Cytokines in Patients with Ankylosing Spondylitis: A Meta-analysis

Ankylosing spondylitis (AS) is a chronic inflammatory disease. Several proinflammatory cytokines produced by T helper 17 (Th17) cells are involved in the pathogenesis of AS. We performed a meta-analysis to det...

Qin-Yi Su, **g-Wen Zheng, **g-Yuan Yang, Tong-Yuan Zhang… in Advances in Therapy (2022)