79 Result(s)

Article

ThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia

In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However, the mechanisms underlying hyperthermia resistance are still poorly under...

Tao-Yan Lin, Jun-Shuang Jia, Wei-Ren Luo… in Journal of Experimental & Clinical Cancer … (2024)

Article

Correction: c-Myc-activated long non-coding RNA LINC01050 promotes gastric cancer growth and metastasis by sponging miR-7161-3p to regulate SPZ1 expression

Ziwei Ji, Tianbin Tang, Mengxia Chen… in Journal of Experimental & Clinical Cancer … (2024)

Article

Invasive FoxM1 phosphorylated by PLK1 induces the polarization of tumor-associated macrophages to promote immune escape and metastasis, amplified by IFITM1

Understanding the mechanism behind immune cell plasticity in cancer metastasis is crucial for identifying key regulators. Previously we found that mitotic factors regulate epithelial-mesenchymal transition, bu...

Rong Xu, Young-Joo Lee, Chang-Hyeon Kim… in Journal of Experimental & Clinical Cancer … (2023)

Article

CHSY1 promotes CD8⁺ T cell exhaustion through activation of succinate metabolism pathway leading to colorectal cancer liver metastasis based on CRISPR/Cas9 screening

The most common site of metastasis in colorectal cancer (CRC) is the liver and liver metastases occur in more than 50% of patients during diagnosis or treatment. The occurrence of metastasis depends on a serie...

Guangshun Sun, Siqi Zhao, Zhongguo Fan… in Journal of Experimental & Clinical Cancer … (2023)

Article

Correction: Energy stress-induced circZFR enhances oxidative phosphorylation in lung adenocarcinoma via regulating alternative splicing

Zhifei Ma, Hao Chen, Zhijun **a, **g You… in Journal of Experimental & Clinical Cancer … (2023)

Article

Energy stress-induced circZFR enhances oxidative phosphorylation in lung adenocarcinoma via regulating alternative splicing

Circular RNAs (circRNAs) contribute to multiple biological functions and are also involved in pathological conditions such as cancer. However, the role of circRNAs in metabolic reprogramming, especially upon e...

Zhifei Ma, Hao Chen, Zhijun **a, **g You… in Journal of Experimental & Clinical Cancer … (2023)

Article

Integrated proteogenomic characterization reveals an imbalanced hepatocellular carcinoma microenvironment after incomplete radiofrequency ablation

Efforts to precisely assess tumor-specific T-cell immune responses still face major challenges, and the potential molecular mechanisms mediating hepatocellular carcinoma (HCC) microenvironment imbalance after ...

Zheng-Rong Shi, Yu-**n Duan, Fang Cui… in Journal of Experimental & Clinical Cancer … (2023)

Article

The β-catenin-LINC00183-miR-371b-5p-Smad2/LEF1 axis promotes adult T-cell lymphoblastic lymphoma progression and chemoresistance

High-intensity chemotherapy regimens are often used in adult T-cell lymphoblastic lymphoma (T-LBL) patients. Nevertheless, the response rate remains unsatisfactory due to emergence of chemoresistance. Growing ...

Wei-Juan Huang, Song-Bin Guo, Hui Shi… in Journal of Experimental & Clinical Cancer … (2023)

Article

A flexible liposomal polymer complex as a platform of specific and regulable immune regulation for individual cancer immunotherapy

The applicability and therapeutic efficacy of specific personalized immunotherapy for cancer patients is limited by the genetic diversity of the host or the tumor. Side-effects such as immune-related adverse e...

Chia-Hung Chen, Tzu-Han Weng… in Journal of Experimental & Clinical Cancer … (2023)

Article

Retraction Note: Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT1 promotes pancreatic cancer growth and metastasis

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-016-0301-7.

Li Huang, Bin Hu, Jianbo Ni, Jianghong Wu… in Journal of Experimental & Clinical Cancer … (2023)

Article

A functional loop between YTH domain family protein YTHDF3 mediated m⁶A modification and phosphofructokinase PFKL in glycolysis of hepatocellular carcinoma

N⁶-methyladenosine (m⁶A) modification plays a critical role in progression of hepatocellular carcinoma (HCC), and aerobic glycolysis is a hallmark of cancer including HCC. However, the role of YTHDF3, one member ...

Rong Zhou, Wen Ni, Chao Qin, Yunxia Zhou… in Journal of Experimental & Clinical Cancer … (2022)

Article

CircPAK1 promotes the progression of hepatocellular carcinoma via modulation of YAP nucleus localization by interacting with 14-3-3ζ

Circular RNA (circRNA), a new class of non-coding RNA, has obvious correlations with the occurrence and development of many diseases, including tumors. This study aimed to investigate the potential roles of ci...

**aopei Hao, Yao Zhang, **aoli Shi… in Journal of Experimental & Clinical Cancer … (2022)

Article

Correction: Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling

Binghong Chen, Mengying Wang, Junjun Qiu… in Journal of Experimental & Clinical Cancer … (2022)

Article

Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling

Abnormal proliferation and migration of cells are hallmarks of cancer initiation and malignancy. Asparagine endopeptidase (AEP) has specific substrate cleavage ability and plays a pro-cancer role in a variety ...

Binghong Chen, Mengying Wang, Junjun Qiu… in Journal of Experimental & Clinical Cancer … (2022)

Article

Retraction Note: TRIM29 facilitates the epithelial‑to-mesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/β-catenin signaling pathway

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-019-1098-y.

Juntao Sun, Tianyu Zhang, Mengmeng Cheng… in Journal of Experimental & Clinical Cancer … (2022)

Article

Emerging therapies for glioblastoma: current state and future directions

Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an extremely poor prognosis. Given the poor survival with currently approved treatments for GBM, new therapeutic strategies a...

Liang Rong, Ni Li, Zhenzhen Zhang in Journal of Experimental & Clinical Cancer Research (2022)

Article

C-Myc-activated long non-coding RNA LINC01050 promotes gastric cancer growth and metastasis by sponging miR-7161-3p to regulate SPZ1 expression

Growing evidence shows that long non-coding RNAs (lncRNAs) play significant roles in cancer development. However, the functions of most lncRNAs in human gastric cancer are still not fully understood. Here, we ...

Ziwei Ji, Tianbin Tang, Mengxia Chen… in Journal of Experimental & Clinical Cancer … (2021)

Article

The novel circSLC6A6/miR-1265/C2CD4A axis promotes colorectal cancer growth by suppressing p53 signaling pathway

Colorectal cancer (CRC) is one of the most frequent malignancy and a leading cause of cancer-related deaths. Therefore, further researches are required to identify novel and more effective diagnoses and to ide...

Zeyin Rong, Zai Luo, Zhongmao Fu… in Journal of Experimental & Clinical Cancer … (2021)

Article

Retraction Note: TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways

Run-Wei Yang, Ying-Yue Zeng, Wen-Ting Wei… in Journal of Experimental & Clinical Cancer … (2021)

Article

Correction to: TRIM29 facilitates the epithelial-tomesenchymal transition and the progression of colorectal cancer via the activation of the Wnt/β-catenin signaling pathway

An amendment to this paper has been published and can be accessed via the original article.

Juntao Sun, Tianyu Zhang, Mengmeng Cheng… in Journal of Experimental & Clinical Cancer … (2021)