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Article
Open AccessModelling the impact of human behavior using a two-layer Watts-Strogatz network for transmission and control of Mpox
This study aims to evaluate the effectiveness of mitigation strategies and analyze the impact of human behavior on the transmission of Mpox. The results can provide guidance to public health authorities on com...
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Article
Open AccessRisk factor analysis and risk prediction study of obesity in steelworkers: model development based on an occupational health examination cohort dataset
Obesity is increasingly recognized as a grave public health concern globally. It is associated with prevalent diseases including coronary heart disease, fatty liver, type 2 diabetes, and dyslipidemia. Prior re...
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Article
Open AccessA nested case-control study of the effects of dust exposure, smoking on COPD in coal workers
Chronic obstructive pulmonary disease (COPD) represents a prevalent ailment, progressively surging within the ranks of coal mine laborers. The current study endeavors to elucidate the effects of dust exposure ...
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Article
Open AccessHaldane topological spin-1 chains in a planar metal-organic framework
Haldane topological materials contain unique antiferromagnetic chains with symmetry-protected energy gaps. Such materials have potential applications in spintronics and future quantum computers. Haldane topolo...
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Article
Open AccessAnalysis of factors affecting nonalcoholic fatty liver disease in Chinese steel workers and risk assessment studies
The global incidence of nonalcoholic fatty liver disease (NAFLD) is rapidly escalating, positioning it as a principal public health challenge with significant implications for population well-being. Given its ...
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Article
Open AccessPulmonary effects of exposure to indium and its compounds: cross-sectional survey of exposed workers and experimental findings in rodents
Many studies have shown that occupational exposure to indium and its compounds could induce lung disease. Although animal toxicological studies and human epidemiological studies suggest indium exposure may cau...
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Article
Open AccessYKL-39 is an independent prognostic factor in gastric adenocarcinoma and is associated with tumor-associated macrophage infiltration and angiogenesis
Gastric cancer has a high incidence and mortality rate. Angiogenesis is necessary for tumor infiltration and metastasis and affects patient prognosis. YKL-39 has monocyte chemotactic activity and pro-angiogeni...
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Article
Long-Term Forecast of HIV/AIDS Epidemic in China with Fear Effect and 90-90-90 Strategies
We formulate a compartmental model considering behavioral changes of susceptible individuals due to fear to assess the transmission dynamics of HIV/AIDS in mainland China. Stability and uniform persistence are...
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Article
Modeling and Evaluation of the Joint Prevention and Control Mechanism for Curbing COVID-19 in Wuhan
The spread of COVID-19 in Wuhan was successfully curbed under the strategy of “Joint Prevention and Control Mechanism.” To understand how this measure stopped the epidemics in Wuhan, we establish a compartment...
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Article
Open AccessPaediatric oncology ward nurses’ experiences of patients’ deaths in China: A qualitative study
Considering cancer death is second only to accidental death in the number of lives claimed each year,nurses in paediatric oncology wards often experience helplessness, sadness, frustration and such other adver...
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Article
Open Accessrno-miR-128-3p promotes apoptosis in rat granulosa cells (GCs) induced by norepinephrine through Wilms tumor 1 (WT1)
The mechanism related to ovarian follicular is complex, which has not been fully elucidated. Abundant reports have confirmed that the ovarian function development is closely related to sympathetic innervation....
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Article
Open AccessAssociation of thrombocytopenia and infection in patients with ST-elevation myocardial infarction undergoing percutaneous coronary intervention
The impact of thrombocytopenia on infection in patients with ST-elevation myocardial infarction (STEMI) remains poorly understood.
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Article
Open AccessImmunization with a fusion protein vaccine candidate generated from truncated peptides of human enterovirus 71 protects mice from lethal enterovirus 71 infections
Prophylactic vaccines are critical in preventing hand, foot, and mouth disease (HFMD) primarily caused by human enterovirus 71 (EV71) infection. Children aged less than 5 years are especially susceptible to EV...
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Article
Chimeric Newcastle disease virus-vectored vaccine protects chickens against H9N2 avian influenza virus in the presence of pre-existing NDV immunity
A chimeric Newcastle disease virus (NDV) vector (NDV/AI4-TFHN) was constructed with the replacement of the ectodomains of the fusion and hemagglutinin-neuraminidase proteins by those from avian paramyxovirus t...
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Article
Open AccessSpin–phonon couplings in transition metal complexes with slow magnetic relaxation
Spin–phonon coupling plays an important role in single-molecule magnets and molecular qubits. However, there have been few detailed studies of its nature. Here, we show for the first time distinct couplings of g ...
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Article
Open AccessTestes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer
TSP50 (testes-specific protease 50) has been reported to be a candidate oncogene and is overexpressed in various cancers. Our previous study demonstrated that TSP50 protein is elevated in gastric cancer, and i...
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Article
Open AccessSpatial-temporal distribution of dengue and climate characteristics for two clusters in Sri Lanka from 2012 to 2016
Dengue is a vector-borne disease causing high morbidity and mortality in tropical and subtropical countries. Urbanization, globalization, and lack of effective mosquito control have lead to dramatically increa...
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Article
Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons
Iron dyshomeostasis is one of the primary causes of neuronal death in Alzheimer's disease (AD). Huperzine A (HupA), a natural inhibitor of acetylcholinesterase (AChE), is a licensed anti-AD drug in China and a...
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Article
Open AccessOverexpression of GOLPH3 is associated with poor prognosis and clinical progression in pancreatic ductal adenocarcinoma
Golgi phosphoprotein 3 (GOLPH3) has been identified as an oncoprotein in various human cancers; however, its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. We examined GOLPH3 expression levels and...
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Article
Open AccessSpecies identification through mitochondrial rRNA genetic analysis
Inter-species and intraspecific variations in mitochondrial DNA (mtDNA) were observed in a bioinformatics analysis of the mitochondrial genomic sequences of 11 animal species. Some highly conserved regions wer...
