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Article
Open AccessOxidized mitochondrial DNA induces gasdermin D oligomerization in systemic lupus erythematosus
Although extracellular DNA is known to form immune complexes (ICs) with autoantibodies in systemic lupus erythematosus (SLE), the mechanisms leading to the release of DNA from cells remain poorly characterized...
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Article
Open AccessThe MAPKKK and MAPKK gene families in banana: identification, phylogeny and expression during development, ripening and abiotic stress
The mitogen-activated protein kinase (MAPK) cascade, which is a major signal transduction pathway widely distributed in eukaryotes, has an important function in plant development and stress responses. However,...
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Article
Open AccessCross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions
Glomerular mesangial cells (MCs) hypertrophy is one of the earliest pathological abnormalities in diabetic nephropathy (DN), which correlates with eventual glomerulosclerosis. This study aimed to investigate t...
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Article
Open AccessGenome-wide analyses of the bZIP family reveal their involvement in the development, ripening and abiotic stress response in banana
The leucine zipper (bZIP) transcription factors play important roles in multiple biological processes. However, less information is available regarding the bZIP family in the important fruit crop banana. In th...