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  1. Article

    Open Access

    SDMA attenuates renal tubulointerstitial fibrosis through inhibition of STAT4

    Renal tubulointerstitial fibrosis is the hallmark of various chronic kidney diseases. Symmetric dimethylarginine (SDMA) is an independent cardiovascular risk factor in patients with chronic kidney diseases, wh...

    Yanzhe Wang, Ming Wu, Dong** Chen, Bo Tan… in Journal of Translational Medicine (2023)

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  2. Article

    Open Access

    Use of proteomics to identify mechanisms of hepatocellular carcinoma with the CYP2D6*10 polymorphism and identification of ANGPTL6 as a new diagnostic and prognostic biomarker

    Although an association between the cytochrome P4502D6 (CYP2D6) *10 (100C>T) polymorphism and hepatocellular carcinoma (HCC) is known, the mechanism remains unclear. Here we aimed to explore mechanisms of CYP2...

    Guiming Hu, Fei Gao, Guanzhe Wang, Yan Fang… in Journal of Translational Medicine (2021)

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  3. Article

    Open Access

    SUMO modification in apoptosis

    Apoptosis and clearance of dead cells is highly evolutionarily conserved from nematode to humans, which is crucial to the growth and development of multicellular organism. Fail to remove apoptotic cells often ...

    Peiyao Li, Huiru **g, Yanzhe Wang, Lei Yuan, Hui **ao… in Journal of Molecular Histology (2021)

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