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Open AccessExtraskeletal myxoid chondrosarcoma in the lung: asymptomatic lung mass with severe anemia
Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft-tissue sarcoma, which primarily occurs deep in the extremities, especially in skeletal muscle, or tendon. EMC of the pleura has been described, however,...
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Article
Open AccessIncreased Krüppel-like factor 12 in recurrent implantation failure impairs endometrial decidualization by repressing Nur77 expression
Decidualization is a prerequisite for successful implantation and the establishment of pregnancy. A critical role of impaired decidualization in subfertility has been established. In human endometrial stromal ...
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Article
Open AccessActivating transcription factor 3 promotes embryo attachment via up-regulation of leukemia inhibitory factor in vitro
A receptive endometrium is essential for maternal-embryonic molecular communication during implantation. However, the specific molecular regulatory mechanisms of the endometrial capacity remain poorly understo...
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Open AccessLow-dose lymphocyte immunotherapy rebalances the peripheral blood Th1/Th2/Treg paradigm in patients with unexplained recurrent miscarriage
The published results regarding lymphocytes immunotherapy for unexplained recurrent miscarriage (uRM) patients are conflicting due to different screening criteria and therapeutic protocols. The objective of th...
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Article
Open AccessHippocampal metabolic differences implicate distinctions between physical and psychological stress in four rat models of depression
Major depressive disorder (MDD) is a heterogeneous and multi-factorial disorder, and the underlying molecular mechanisms remain largely unknown. However, many studies have indicated that the molecular mechanis...
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Open AccessInfluence of surgical evacuation on pregnancy outcomes of subsequent embryo transfer cycle following miscarriage in an initial IVF cycle: a retrospective cohort study
It is still uncertain whether surgical evacuation adversely affects subsequent embryo transfer. The present study aims to assess the influence of surgical evacuation on the pregnancy outcomes of subsequent emb...
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Article
Open AccessPlatelet-expressed immune checkpoint regulator GITRL in breast cancer
Owing to their key role in several diseases including cancer, activating and inhibitory immune checkpoint molecules are increasingly exploited as targets for immunotherapy. Recently, we demonstrated that plate...
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Article
Open AccessMelatonin enhances SIRT1 to ameliorate mitochondrial membrane damage by activating PDK1/Akt in granulosa cells of PCOS
Mitochondrial injury in granulosa cells (GCs) is associated with the pathophysiological mechanism of polycystic ovary syndrome (PCOS). Melatonin reduces the mitochondrial injury by enhancing SIRT1 (NAD-depende...
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Article
Open AccessExcess fatty acids induce pancreatic acinar cell pyroptosis through macrophage M1 polarization
Free fatty acid derived from hyperlipidemia contributes to the development of inflammation in the pancreas. Here we explore the molecular mechanisms of fatty acid-induced pancreatitis through cellular experime...
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Article
Open AccessInstruments to measure e-cigarette related constructs: a systematic review
Electronic cigarettes (e-cigarettes) are relatively new tobacco products that are attracting public attention due to their unique features, especially their many flavor options and their potential as an altern...
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Article
Open AccessStudy of T2 map** in quantifying and discriminating uterine lesions under different magnetic field strengths: 1.5 T vs. 3.0 T
MRI is the best imaging tool for the evaluation of uterine tumors, but conventional MRI diagnosis results rely on radiologists and contrast agents (if needed). As a new objective, reproducible and contrast-age...
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Open AccessPerinatal outcomes of singletons following double vitrification-warming procedures: a retrospective study using propensity score analysis
Although repeated cryopreservation is an occasional occurrence, the effect on perinatal outcomes is unclear. Therefore, the aim of this study was to evaluate the perinatal outcomes of singletons after embryo r...
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Open AccessAn update on fractional picosecond laser treatment: histology and clinical applications
Picosecond lasers have a very short pulse duration and a high peak power density. When fractional optical delivery systems are attached to picosecond lasers, they generate an array of concentrated microspots w...
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Open AccessCorrection: Perinatal outcomes of singletons following double vitrification-warming procedures: a retrospective study using propensity score analysis
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Open AccessSystematic review: interventions to quit tobacco products for young adults
Young adulthood is an important period for smoking cessation; however, there is limited evidence of smoking-cessation interventions for young adults. The aims of this study were to identify evidence-based smok...
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Open AccessThe CD2v protein of African swine fever virus inhibits macrophage migration and inflammatory cytokines expression by downregulating EGR1 expression through dampening ERK1/2 activity
African swine fever virus (ASFV) is a highly contagious and deadly virus that leads to high mortality rates in domestic swine populations. Although the envelope protein CD2v of ASFV has been implicated in immu...
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Open AccessLiver fat volume fraction measurements based on multi-material decomposition algorithm in patients with nonalcoholic fatty liver disease: the influences of blood vessel, location, and iodine contrast
In recent years, spectral CT-derived liver fat quantification method named multi-material decomposition (MMD) is playing an increasingly important role as an imaging biomarker of hepatic steatosis. However, th...
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Open AccessAnalysis of factors related to osteoporotic vertebral fracture in prostate cancer patients
This study was aimed at exploring the osteoporotic vertebral fracture rate and the related causal factors in prostate cancer patients before and after treatment.
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Open AccessStudy protocol: a core outcome set for perioperative exercise clinical effectiveness trials for lung cancer patients
Outcome assessment in perioperative exercise trials for lung cancer is heterogeneous, often omitting those that are important and patient-relevant. This heterogeneity hinders the synthesis of evidence. To addr...
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Open AccessRadiomics predict the WHO/ISUP nuclear grade and survival in clear cell renal cell carcinoma
This study aimed to assess the predictive value of radiomics derived from intratumoral and peritumoral regions and to develop a radiomics nomogram to predict preoperative nuclear grade and overall survival (OS...