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    Article

    SOX10 is a novel oncogene in hepatocellular carcinoma through Wnt/β-catenin/TCF4 cascade

    SOX (high mobility group) genes play an important role in a number of developmental processes. Potential roles of SOXs have been demonstrated in various neoplastic tissues as tumor suppressors or promoters dep...

    Dangjun Zhou, Fengjiao Bai, **nning Zhang, Minggen Hu, Guodong Zhao in Tumor Biology (2014)

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    Open Access

    Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis

    Temozolomide (TMZ) represents a standard-of-care chemotherapeutic agent in glioblastoma (GBM). However, the development of drug resistance constitutes a significant hurdle in the treatment of malignant glioma....

    Yuanliang Yan, Shangjun Zhou, ** Chen in Signal Transduction and Targeted Therapy (2024)