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  1. Article

    Open Access

    FOXQ1 promotes pancreatic cancer cell proliferation, tumor stemness, invasion and metastasis through regulation of LDHA-mediated aerobic glycolysis

    Pancreatic cancer (PC), a gastrointestinal tract malignant tumor, has a poor prognosis due to early metastasis and limited response to chemotherapy. Therefore, identifying novel therapeutic approaches for PC i...

    Changhao Wu, Chenglong Zheng, Shiyu Chen, Zhiwei He, Hao Hua… in Cell Death & Disease (2023)

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  2. No Access

    Article

    RNAi Silencing of HIF-1α Ameliorates Lupus Development in MRL/lpr Mice

    Th17 cell and IL-17-mediated autoimmunity and inflammatory responses have been implicated in the development of organ damage in systemic lupus erythematosus (SLE), and new evidence suggests that hypoxia-induci...

    Wei Zhao, Changhao Wu, Lian-Ju Li, Yin-Guang Fan, Hai-Feng Pan, **-Hui Tao… in Inflammation (2018)