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Article
Soil Total Nitrogen Mediated the Impact of Climatic Factors on Urban Soil Organic Matter Under Different Land Uses
The **ong'an New Area (XNA) is a nationally designated region characterized by prominent emerging trends, intensive human activities, and rapid urbanization. However there needs to be more clarity regarding th...
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Article
From Soil to Soul: Agro-Product Geographical Indications and the Subjective Well-Being of Rural Residents
Based on 2022 data from the China Rural Revitalization Survey, we examined the impact of Agro-product Geographical Indications (AGIs) on the subjective well-being of rural residents. The results show that AGIs...
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Article
Open AccessEnhancing efficiency of protein language models with minimal wet-lab data through few-shot learning
Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Pre-trained protein language models have achieved state-of-the-art performance in predicting protein fitness w...
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Article
A universal calibration method for eliminating topography-dependent current in conductive AFM and its application in nanoscale imaging
The topography and electrical properties are two crucial characteristics that determine the roles and functionalities of materials. Conductive atomic force microscopy (CAFM) is widely recognized for its abilit...
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Article
Efficacy of transcutaneous electrical nerve stimulation combined with mirabegron therapy compared with mirabegron monotherapy for overactive bladder: a prospective randomized controlled study
The objective was to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) combined with mirabegron therapy compared with mirabegron monotherapy in the treatment of female patients with o...
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Article
Open AccessHigh mortality associated with inappropriate initial antibiotic therapy in hematological malignancies with Klebsiella pneumoniae bloodstream infections
Bloodstream infections caused by multidrug-resistant organisms such as Klebsiella pneumoniae are a significant challenge in managing hematological malignancies. This study aims to characterize the epidemiology of...
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Article
Trade-off of lifting and propulsion capacity of tandem flap**-fixed airfoils by inclining the stroke plane
A tandem flap**-fixed airfoil configuration with a narrow gap can be found in insects and micro air vehicles (MAVs). Compared to a single flap** airfoil, the interaction between the two airfoils can bring ...
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Article
Thylakoid engineered M2 macrophage for sonodynamic effect promoted cell therapy of early atherosclerosis
Atherosclerosis is the most common cause of cardiovascular diseases that contribute to the major morbidity worldwide, but still lacking of effective treatment strategy. Here, a hybrid cell is constructed for t...
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Article
Open AccessSpecific lipid magnetic sphere sorted CD146-positive bone marrow mesenchymal stem cells can better promote articular cartilage damage repair
The characteristics and therapeutic potential of subtypes of bone marrow mesenchymal stem cells (BMSCs) are largely unknown. Also, the application of subpopulations of BMSCs in cartilage regeneration remains p...
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Article
Open AccessNovel inhalation therapy in pulmonary fibrosis: principles, applications and prospects
Pulmonary fibrosis (PF) threatens millions of people worldwide with its irreversible progression. Although the underlying pathogenesis of PF is not fully understood, there is evidence to suggest that the disea...
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Article
Open AccessTraditional Chinese medicine inspired dual-drugs loaded inhalable nano-therapeutics alleviated idiopathic pulmonary fibrosis by targeting early inflammation and late fibrosis
Idiopathic pulmonary fibrosis (IPF) is a highly debilitating and fatal chronic lung disease that is difficult to cure clinically. IPF is characterized by a gradual decline in lung function, which leads to resp...
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Chapter and Conference Paper
Self-propulsive Performance of Tandem Flap**-Fixed Airfoils at Low Reynolds Number: A Case Study
Tandem airfoils or hydrofoils have been extensively observed in both natural flyers or swimmers and aircraft. Dragonflies can achieve excellent flights by adjusting the phase difference and wake interaction of...
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Chapter and Conference Paper
Propulsion Performance of Multiple Pitching-Heaving Airfoils in Side-by-Side Configurations
In nature, flying animals and swimming fishes flap their wings or fins to achieve excellent movements within the low Reynolds number regime. Their complex flap** kinematics are often reasonably simplified in...
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Article
Open AccessCD146-positive adipose-derived stem cells subpopulation enriched by albumin magnetic sphere ameliorates knee osteoarthritis pain and promotes cartilage repair
The use of adipose stem cell (ADSCs) subpopulations in cartilage repair remains poorly characterized. In this study, we constructed an albumin magnetic sphere with specific targeting of CD146 (CD146-AMs) for s...
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Article
Open AccessSingle-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain
Cytosine DNA methylation is essential in brain development and is implicated in various neurological disorders. Understanding DNA methylation diversity across the entire brain in a spatial context is fundament...
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Article
Open AccessFOXQ1 promotes pancreatic cancer cell proliferation, tumor stemness, invasion and metastasis through regulation of LDHA-mediated aerobic glycolysis
Pancreatic cancer (PC), a gastrointestinal tract malignant tumor, has a poor prognosis due to early metastasis and limited response to chemotherapy. Therefore, identifying novel therapeutic approaches for PC i...
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Article
New evidence on the impact of No-tillage management on agricultural carbon emissions
Controlling agricultural carbon emissions contributes to achieving peak carbon emissions and carbon neutrality. However, as a conservation management practice of farmland, the impact of No-tillage management (...
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Article
Open AccessProteomic profiling of gastric cancer with peritoneal metastasis identifies a protein signature associated with immune microenvironment and patient outcome
Peritoneal metastasis (PM) frequently occurs in patients with gastric cancer (GC) and is a major cause of mortality. Risk stratification for PM can optimize decision making in GC treatment.
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Article
Open AccessThe effect of integrity of lesser tuberosity-medial calcar on postoperative outcome in the proximal humeral fracture
In proximal humeral fractures, the medial calcar is often considered an important stabilizing structure. When the medial calcar is disrupted, some patients may have accompanying humeral lesser tuberosity commi...
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Article
Open AccessSpecialty preferences of studying-abroad medical students from low- and middle-income countries
This study explored the specialty preferences of China-educated international medical students (IMSs), who are mainly from low- and middle-income countries (LMICs) and constitute a potential medical workforce ...