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Article
Open AccessImmune checkpoint inhibitors as the second-line treatment for advanced esophageal squamous cell carcinoma: a cost-effectiveness analysis based on network meta-analysis
Immune checkpoint inhibitors (ICIs) have demonstrated superior clinical efficacy in prolonging overall survival (OS) as the second-line treatment for advanced or metastatic esophageal squamous cell carcinoma (...
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Article
Isolation of the inorganic phosphorus-solubilizing bacteria Lysinibacillus sphaericus and assessing its role in promoting rice growth
Soluble phosphorus scarcity severely limits plant growth and crop yield. In this study, a strain of inorganic phosphorus-solubilizing bacteria, Lysinibacillus sphaericus, was isolated from rice rhizosphere soil. ...
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Article
Open AccessTwo telomere-to-telomere gapless genomes reveal insights into Capsicum evolution and capsaicinoid biosynthesis
Chili pepper (Capsicum) is known for its unique fruit pungency due to the presence of capsaicinoids. The evolutionary history of capsaicinoid biosynthesis and the mechanism of their tissue specificity remain obsc...
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Article
Analytical Expression for the Atomic Friction of a Single Asperity Based on the Prandtl–Tomlinson Model
The Prandtl–Tomlinson (PT) model has been widely applied to interpret the atomic friction mechanism of a single asperity. In this study, we present an approximate explicit expression for the friction force in ...
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Article
Open AccessUltra-photostable small-molecule dyes facilitate near-infrared biophotonics
Long-wavelength, near-infrared small-molecule dyes are attractive in biophotonics. Conventionally, they rely on expanded aromatic structures for redshift, which comes at the cost of application performance suc...
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Article
Study on the damage mechanism of granite containing prefabricated non-through joints
This study conducts uniaxial compression tests on granite samples with prefabricated fissures to investigate the damage mechanism of granite containing non-penetrating joints. These tests combine indoor experi...
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Article
Open AccessIdentification of mine water sources using a multi-dimensional ion-causative nonlinear algorithmic model
Based on the nonlinear algorithmic theory, the R-SVM water source discrimination model and prediction method were established by using the piper qualitatively to compare the differences between the ionic compo...
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Article
Open AccessResearch on the prediction of mine water inrush disasters based on multi-factor spatial game reconstruction
Water damage in mines poses a widespread challenge in the coal mining industry. Gaining a comprehensive understanding of the multi-factor spatial catastrophe evolution mechanism and process of floor water inru...
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Article
Open AccessSelf-propelled assembly of nanoparticles with self-catalytic regulation for tumour-specific imaging and therapy
Targeted assembly of nanoparticles in biological systems holds great promise for disease-specific imaging and therapy. However, the current manipulation of nanoparticle dynamics is primarily limited to organic...
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Article
Open AccessDe novo chromosome-level genome assembly of Chinese motherwort (Leonurus japonicus)
Chinese motherwort (Leonurus japonicus), a member of Lamiaceae family, is a commonly used medicinal herb for treating obstetrical and gynecological diseases, producing over 280 officinal natural products. Due to ...
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Article
Development of Megaselia scalaris at constant temperatures and its significance in estimating the time of death
Megaselia scalaris (Schmitz, 1938) (Diptera: Phoridae) is a common insect in forensic science that is frequently found in indoor cases, particularly on corpses in closed environments. Although this species is us...
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Article
Numerical Study on Pilot Ignition of a Thermally-Thick Solid Fuel with Low-Velocity Airflow in Microgravity
The mechanisms controlling the dependence on low-velocity flow of the piloted ignition of a solid material under external radiant heating is investigated through a numerical modeling. The poly (methyl methacry...
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Article
Open AccessCognitive decline as the main manifestation of diabetic striatal disease but without involuntary movements: a case report
Diabetic striatopathy (DS) is a rare central nervous system complication of diabetes mellitus, characterized mainly by non-ketotic hyperglycemia and lateralized involuntary movements. Patients with diabetic st...
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Article
Fluorescence-amplified nanocrystals in the second near-infrared window for in vivo real-time dynamic multiplexed imaging
Optical imaging in the second near-infrared window (NIR-II, 1,000–1,700 nm) holds great promise for non-invasive in vivo detection. However, real-time dynamic multiplexed imaging remains challenging due to the...
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Article
A global perspective of forensic entomology case reports from 1935 to 2022
Forensic entomology case reports are the product of rapid development in the field, the widespread acceptance of the science and the application of forensic entomological knowledge. In this study, we retrospec...
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Article
Interactive medical image segmentation with self-adaptive confidence calibration
Interactive medical image segmentation based on human-in-the-loop machine learning is a novel paradigm that draws on human expert knowledge to assist medical image segmentation. However, existing methods often...
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Article
An alternating structure-adapted Bregman proximal gradient descent algorithm for constrained nonconvex nonsmooth optimization problems and its inertial variant
We consider the nonconvex nonsmooth minimization problem over abstract sets, whose objective function is the sum of a proper lower semicontinuous biconvex function of the entire variables and two smooth noncon...
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Article
Influence of Hybrid Ratios on Shape Memory Properties of Basalt/Carbon Fiber Hybrid Composites with Graphene Oxide Prepared by VIHPS
A study on the shape memory properties of 6 layers bi-directional basalt fiber/carbon fiber hybrid composites with graphene oxide (GO) was presented in this paper. The hybrid composites were prepared by the va...
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Article
A hybrid approach of case- and rule-based reasoning to assembly sequence planning
This paper presents a case-based reasoning (CBR) method in combination with ontology theory to carry out decision making for assembly sequence planning (ASP). Due to the ontology unifying various kinds of asse...
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Article
Open AccessHeritable transgene-free genome editing in plants by grafting of wild-type shoots to transgenic donor rootstocks
Generation of stable gene-edited plant lines using clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein 9 (Cas9) requires a lengthy process of outcrossing to eliminate C...
