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Article
Open AccessParabacteroides distasonis uses dietary inulin to suppress NASH via its metabolite pentadecanoic acid
Non-alcoholic steatohepatitis (NASH) is the severe form of non-alcoholic fatty liver disease, and is characterized by liver inflammation and fat accumulation. Dietary interventions, such as fibre, have been sh...
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Article
Open AccessMeta-analysis of mucosal microbiota reveals universal microbial signatures and dysbiosis in gastric carcinogenesis
The consistency of the associations between gastric mucosal microbiome and gastric cancer across studies remained unexamined. We aimed to identify universal microbial signatures in gastric carcinogenesis throu...
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Article
Open AccessAuthor Correction: Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids
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Article
Integrative metabolomic characterization identifies plasma metabolomic signature in the diagnosis of papillary thyroid cancer
Discrimination of malignancy from thyroid nodules poses challenges in clinical practice. We aimed to identify the plasma metabolomic biomarkers in discriminating papillary thyroid cancer (PTC) from benign thyr...
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Article
Open AccessAltered gut metabolites and microbiota interactions are implicated in colorectal carcinogenesis and can be non-invasive diagnostic biomarkers
Gut microbiota contributes to colorectal cancer (CRC) pathogenesis through microbes and their metabolites. The importance of microbiota-associated metabolites in colorectal carcinogenesis highlights the need t...
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Article
Open AccessStructure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids
Bacterial type IV secretion systems (T4SSs) are largely responsible for the proliferation of multi-drug resistance. We solved the structure of the outer-membrane core complex (OMCCF) of a T4SS encoded by a conjug...
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Article
Open AccessPrediction of all-cause mortality in coronary artery disease patients with atrial fibrillation based on machine learning models
Machine learning (ML) can include more diverse and more complex variables to construct models. This study aimed to develop models based on ML methods to predict the all-cause mortality in coronary artery disea...
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Article
Molecular dynamics investigation of structure evolution and thermodynamics of Ni–Fe nanoparticles during inert gas condensation
Synthesis of magnetic nanoparticles is relevant to many applications in the fields of catalysis, energy storage, and biomedicine. Understanding the growth mechanisms and morphology of nanoparticles during iner...
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Article
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy
Synucleinopathies are neurodegenerative diseases that are associated with the misfolding and aggregation of α-synuclein, including Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy1. Clin...
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Chapter and Conference Paper
Design and Application of Automatic Monitoring and BIM Technology to the Construction of Shield-Bored Underneath Building
Shield cutting pile foundation through the buildings has a significant impact on the safety of the building surface. Traditional measurement cannot meet the need of the project. This paper takes Building 9–13 ...
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Chapter and Conference Paper
Optimization of Location of Robotic Total Station in 3D Deformation Monitoring of Multiple Points
This paper described an optimization method of deciding the location of RTS (robotic total station) in 3D deformation monitoring of multiple points, which was widely applied in deformation/displacement monitor...
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Chapter and Conference Paper
Multisensory System Research for Large Area Deformation Based on Optical Measuring with UAV and Ground Visual Assists
The monitoring for large-area deformations for the constructions in process or the natural regions which are hard for people to get close to is a challenge work. And the combination of Unmanned Aerial Vehicle ...
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Article
Open AccessmiR-29c-3p regulates DNMT3B and LATS1 methylation to inhibit tumor progression in hepatocellular carcinoma
Accumulating evidence suggests that microRNAs and DNA methylation can cause tumor suppressor gene inactivation and promote tumor malignancy. However, the functional mechanisms of miR-29c-3p and DNA methylation...
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Chapter and Conference Paper
Optimization of Location of Robotic Total Station in Tunnel Deformation Monitoring
This paper described an optimization method of deciding the location of RTS (robotic total station) in tunnel deformation monitoring of a series of points. Normally the method of resection and polar coordinate...
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Chapter and Conference Paper
An Internet Based Intelligent System for Early Concrete Curing in Underground Structures
This paper described a newly developed internet based intelligent early concrete curing system for underground structure construction. The system was composed of field measuring and controlling subsystem (incl...
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Chapter and Conference Paper
Simplified Vibration Control Technique of Monitoring Devices in Operating Tunnels
Automated TS (total stations) have been widely utilized in the displacement monitoring of underground structures during neighboring constructions. However, in operating tunnels the vibration of both walls and ...
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Article
Open AccessThe use of 5-fluorouracil-loaded nanobubbles combined with low-frequency ultrasound to treat hepatocellular carcinoma in nude mice
This study aimed to investigate the therapeutic effects of 5-fluorouracil (5-FU)-loaded nanobubbles irradiated with low-intensity, low-frequency ultrasound in nude mice with hepatocellular carcinoma (HCC).
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Chapter
Shaking Model Tests on Liquefaction Mitigation of Embedded Lifeline
The gigantic earthquake in 2011 caused significant damage in lifeline in the Tokyo Metropolitan area. In particular, the damage was significant in recent artificial islands where liquefaction affected embedded...
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Article
Open AccessAn atomic model of brome mosaic virus using direct electron detection and real-space optimization
Advances in electron cryo-microscopy have enabled structure determination of macromolecules at near-atomic resolution. However, structure determination, even using de novo methods, remains susceptible to model bi...
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Chapter and Conference Paper
A Web-Based Practice Teaching System in Collaboration with Enterprise
It is very important for undergraduate students to learn how to apply the theoretical knowledge to the practical business work. However, the widening gap between the engineering education and the real-world ha...
