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  1. No Access

    Article

    Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma

    The clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma (ND-DLBCL) remains largely unexplored. One hundred ND-DLBCL patients were consecutively enrolled as training c...

    **-Hua Liang, Yi-Fan Wu, Hao-Rui Shen, Yue Li, Jun-Heng Liang, Rui Gao in Leukemia (2024)

  2. Article

    Open Access

    Safety, immunogenicity and protective effect of sequential vaccination with inactivated and recombinant protein COVID-19 vaccine in the elderly: a prospective longitudinal study

    The safety and efficacy of COVID-19 vaccines in the elderly, a high-risk group for severe COVID-19 infection, have not been fully understood. To clarify these issues, this prospective study followed up 157 eld...

    Hong-Hong Liu, Yunbo **e, Bao-Peng Yang in Signal Transduction and Targeted Therapy (2024)

  3. Article

    Open Access

    Further clarification of cognitive processes of prospective memory in schizophrenia by comparing eye-tracking and ecologically-valid measurements

    The aim of this study is to compare ecologically-valid measure (the Cambridge Prospective Memory Test, CAMPROMPT) and laboratory measure (eye-tracking paradigm) in assessing prospective memory (PM) in individu...

    Hang Li, Qi Wang, Wen-Peng Hou, Dong-Yang Chen, Yu-Shen Ding in Schizophrenia (2024)

  4. No Access

    Article

    Immunomodulatory Function of Pien Tze Huang in T Cell-Mediated Anti-tumor Activity against B16–F10, MC38 and Hep1-6 Tumor Models

    To investigate the anti-tumor effects of Pien Tze Huang (PZH) in mouse models of B16–F10 melanoma, MC38 colorectal cancer, Hep1-6 hepatocellular carcinoma and chemically induced hepatocellular carcinoma model.

    Yu-bing Fu, Chen-feng Liu, **-jia Wang in Chinese Journal of Integrative Medicine (2024)

  5. Article

    Open Access

    Digital health literacy and associated factors among internet users from China: a cross-sectional study

    As the internet develops and 5G technology becomes increasingly prominent, the internet has become a major source of health-related information. Increasingly, people use the internet to find health-related inf...

    Bing-Yue Zhao, Long Huang, **ao Cheng, Ting-Ting Chen, Si-Jia Li in BMC Public Health (2024)

  6. No Access

    Article

    Electroacupuncture Promotes Functional Recovery after Facial Nerve Injury in Rats by Regulating Autophagy via GDNF and PI3K/mTOR Signaling Pathway

    To explore the mechanism of electroacupuncture (EA) in promoting recovery of the facial function with the involvement of autophagy, glial cell line-derived neurotrophic factor (GDNF), and phosphatidylinositol-...

    Jun-peng Yao, **u-mei Feng, Lu Wang, Yan-qiu Li in Chinese Journal of Integrative Medicine (2024)

  7. No Access

    Article

    Association between alcohol consumption and sleep traits: observational and mendelian randomization studies in the UK biobank

    Previous studies have shown that excessive alcohol consumption is associated with poor sleep. However, the health risks of light-to-moderate alcohol consumption in relation to sleep traits (e.g., insomnia, sno...

    Jun-Wei Zheng, Si-Zhi Ai, Su-Hua Chang, Shi-Qiu Meng, Le Shi in Molecular Psychiatry (2024)

  8. Article

    Open Access

    Correction: A cross-sectional study: family communication, anxiety, and depression in adolescents: the mediating role of family violence and problematic internet use

    **n-cheng Huang, Yue-ning Zhang, **ao-yu Wu, Yang Jiang, Hao Cai in BMC Public Health (2023)

  9. Article

    Open Access

    A cross-sectional study: family communication, anxiety, and depression in adolescents: the mediating role of family violence and problematic internet use

    The objective of this study is to explore the relationship between family communication, family violence, problematic internet use, anxiety, and depression and validate their potential mediating role.

    **n-cheng Huang, Yue-ning Zhang, **ao-yu Wu, Yang Jiang, Hao Cai in BMC Public Health (2023)

  10. No Access

    Article

    Is There Re-staging Surgery Necessity for Borderline Ovarian Tumors

    This study assessed the necessity of surgical re-staging in women with borderline ovarian tumors (BOTs) and evaluated the impact of complete surgical staging, lymphadenectomy, and omentectomy on disease recurr...

    Li-li Guo, **ao-yan Kang, Yue Su, **ao-yu Liu, Xue Wu, Wan **e in Current Medical Science (2023)

  11. Article

    Open Access

    Analysis of mRNA-miRNA interaction network reveals the role of CAFs-derived exosomes in the immune regulation of oral squamous cell carcinoma

    Cancer-associated fibroblasts (CAFs) have significant tumor regulatory functions, and CAFs-derived exosomes (CAFs-Exo) released from CAFs play an important role in the progression of oral squamous cell carcino...

    Wei-Zhou Wang, Xue Cao, Li Bian, Yue Gao, Ming Yu, Yi-Ting Li, Jian-Guo Xu in BMC Cancer (2023)

  12. No Access

    Article

    HIF1α-mediated transactivation of WTAP promotes AML cell proliferation via m6A-dependent stabilization of KDM4B mRNA

    Hypoxia inducible factor 1α (HIF1α) is abnormally overexpressed in t(8;21) acute myeloid leukemia (AML) and functions as an oncogene through transactivating DNA methyltransferase 3 alpha leading to DNA hyperme...

    Yang-Liu Shao, Yu-Qing Li, Meng-Yue Li, Li-Li Wang, Hui-Sheng Zhou in Leukemia (2023)

  13. Article

    Open Access

    The deficient cue monitoring and the facilitating effect of prosocial intention on prospective memory in patients with schizophrenia spectrum disorders

    The study aimed to investigate the cognitive processing of prospective memory (PM) in patients with schizophrenia spectrum disorders (SSDs) by using an eye-tracking paradigm. In addition, the facilitating effe...

    Dong-Yang Chen, Qi Wang, Ning-Bo Yang, **ao-**g Qin, Hang Li in Schizophrenia (2023)

  14. Article

    Open Access

    Cost-effectiveness of the screen-and-treat strategies using HPV test linked to thermal ablation for cervical cancer prevention in China: a modeling study

    Self-sampling HPV test and thermal ablation are effective tools to increase screening coverage and treatment compliance for accelerating cervical cancer elimination. We assessed the cost-effectiveness of their...

    Xue-Lian Zhao, Shuang Zhao, Chang-Fa **a, Shang-Ying Hu, **an-Zhi Duan in BMC Medicine (2023)

  15. Article

    Truncating PICK1 Variant Identified in Azoospermia Affected Mitochondrial Dysfunction in Knockout Mice

    The protein interacting with C kinase 1 (PICK1) plays a critical role in vesicle trafficking, and its deficiency in sperm cells results in abnormal vesicle trafficking from Golgi to acrosome, which eventually dis...

    Yao-qiang Du, Chong-yi Shu, Min Zheng, Wei-de Xu, Yue Sun in Current Medical Science (2023)

  16. Article

    Open Access

    The effects of the prognostic biomarker SAAL1 on cancer growth and its association with the immune microenvironment in lung adenocarcinoma

    Inhibition of Serum Amyloid A-like 1 (SAAL1) expression could inhibit cancer progression and improve the prognosis of cancer patients. At present, the correlation between SAAL1 and lung adenocarcinoma (LAC) re...

    Song Tong, Ni Jiang, Jun-Hao Wan, Chong-Rui Chen, Si-Hua Wang, Chuang-Yan Wu in BMC Cancer (2023)

  17. Article

    Open Access

    Clinical efficacy and complications of transurethral resection of the prostate versus plasmakinetic enucleation of the prostate

    Benign prostatic hyperplasia (BPH) is a common disease in elderly males, and many kinds of minimally invasive procedures can be used for the treatment of BPH. However, various procedures have caused some contr...

    Chong-Yi Yang, Ge-Ming Chen, Yue-**ang Wu in European Journal of Medical Research (2023)

  18. Article

    Open Access

    Inhibition of USP1 reverses the chemotherapy resistance through destabilization of MAX in the relapsed/refractory B-cell lymphoma

    The patients with relapsed and refractory diffuse large B-cell lymphoma (DLBCL) have poor prognosis, and a novel and effective therapeutic strategy for these patients is urgently needed. Although ubiquitin-spe...

    **-Ya Li, Ji-Chuan Wu, ** Liu, Zi-Juan Li, Yong Wang, Bing-Yi Chen in Leukemia (2023)

  19. Article

    Open Access

    Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder

    The nucleus accumbens (NAc) is considered a hub of reward processing and a growing body of evidence has suggested its crucial role in the pathophysiology of major depressive disorder (MDD). However, inconsiste...

    Yu-Dan Ding, **ao Chen, Zuo-Bing Chen, Le Li, Xue-Ying Li in Translational Psychiatry (2022)

  20. Article

    Hypertension Exacerbates Severity and Outcomes of COVID-19 in Elderly Patients: A Retrospective Observational Study

    To evaluate the impact of hypertension on the clinical outcome of COVID-19 patients aged 60 years old and older.

    Li-song Dai, Meng-pei Zhu, Yu-min Li, Hong-mei Zhou in Current Medical Science (2022)

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