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Article
Gliclazide Ameliorates Neuronal Injury by Attenuating Oxidative Stress in D-gal-Induced Senescent Cells and Aging Mice
Enhancement of oxidative stress and resultant neuronal injury play important roles in initiating cognitive impairment during the aging process. Thus, attenuating oxidative injury is regarded as a profitable th...
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Article
The impact of previous abdominal surgery on colorectal cancer patients undergoing laparoscopic surgery
The current study aimed to investigate whether previous abdominal surgery (PAS) could affect the outcomes of colorectal cancer (CRC) surgery. We conducted the search strategy in three databases (PubMed, Embase...
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Article
Open AccessTargeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation of lipid contents and chronic inflammation. Traditional strategies primarily focus on lipid redu...
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Article
Sex-specific impact of dietary patterns on liver cancer incidence: updated results from two population-based cohort studies in China
The associations between dietary patterns and liver cancer risk have received much attention, but evidence among the Chinese population is scarce. This study aims to update the results of two cohort studies an...
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Article
Open AccessAuthor Correction: Amyloid modifier SERF1a interacts with polyQ-expanded huntingtin-exon 1 via helical interactions and exacerbates polyQ-induced toxicity
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Article
Open AccessThe rise of baobab trees in Madagascar
The baobab trees (genus Adansonia) have attracted tremendous attention because of their striking shape and distinctive relationships with fauna1. These spectacular trees have also influenced human culture, inspir...
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Article
Constructing artificial gap junctions to mediate intercellular signal and mass transport
Natural gap junctions are a type of channel protein responsible for intercellular signalling and mass communication. However, the scope of applications for these proteins is limited as they cannot be prepared ...
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Article
Open AccessMerit of integrating in situ transcriptomics and anatomical information for cell annotation and lineage construction in single-cell analyses of Populus
Cell type annotation and lineage construction are two of the most critical tasks conducted in the analyses of single-cell RNA sequencing (scRNA-seq). Four recent scRNA-seq studies of differentiating xylem prop...
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Article
Kinesin-7 CENP-E mediates chromosome alignment and spindle assembly checkpoint in meiosis I
In eukaryotes, meiosis is the genetic basis for sexual reproduction, which is important for chromosome stability and species evolution. The defects in meiosis usually lead to chromosome aneuploidy, reduced gam...
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Article
Exploring genetic diversity and population structure of the Little Tern (Sternula albifrons) in Taiwan based on mtDNA and ddRAD sequencing data
In this study, Little Tern (Sternula albifrons) populations in Taiwan are examined based on two different types of data: mitochondrial control region DNA sequences and double digest restriction-site associated DN...
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Article
Open AccessPublisher Correction: The RNA-binding domain of DCL3 is required for long-distance RNAi signaling
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Article
Open AccessThe RNA-binding domain of DCL3 is required for long-distance RNAi signaling
Small RNA (sRNA)-mediated RNA silencing (also known as RNA interference, or RNAi) is a conserved mechanism in eukaryotes that includes RNA degradation, DNA methylation, heterochromatin formation and protein tr...
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Article
Open AccessClinical and genetic architecture of a large cohort with auditory neuropathy
Auditory neuropathy (AN) is a unique type of language developmental disorder, with no precise rate of genetic contribution that has been deciphered in a large cohort. In a retrospective cohort of 311 patients ...
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Article
Insight into structural degradation of NCMs under extreme fast charging process
Lithium-ion batteries (LIBs) with extreme fast charging (XFC) capability are considered an effective way to alleviate range anxiety for electric vehicle (EV) buyers. Owing to the high ionic and electronic cond...
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Article
Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits
The cerebral ventricles are recognized as windows into brain development and disease, yet their genetic architectures, underlying neural mechanisms and utility in maintaining brain health remain elusive. Here ...
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Article
NνDEx-100 conceptual design report
Observing nuclear neutrinoless double beta (0 \(\nu \beta \beta\) ν ...
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Article
Mechanoluminescence of metal complexes: Progress and applications
Mechanoluminescence (ML) is a light emission phenomenon caused by mechanical force on a substance. Recently, metal complexes mechanoluminescence materials are attracting widespread attention owing to their dis...
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Article
Associations of prenatal exposure to bisphenols with BMI growth trajectories in offspring within the first two years: evidence from a birth cohort study in China
Prenatal bisphenol exposure has been reported to be associated with lower birth weight and obesity-related indicators in early childhood. These findings warrant an investigation of the relationship between pre...
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Article
mTORC2 acts as a gatekeeper for mTORC1 deficiency-mediated impairments in ILC3 development
Group 3 innate lymphoid cells (ILC3s) are mediators of intestinal immunity and barrier function. Recent studies have investigated the role of the mammalian target of rapamycin complex (mTOR) in ILC3s, whereas ...
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Article
The formation of proto-austronesians: insights from a revised phylogeography of the paternal founder lineage
Previous studies suggested that the Y-chromosome haplogroups O2-N6-B451-AM01756 and O1a-M119 are two founder lineages of proto-Austronesians at about five thousand years ago. The objective of this study was to...
