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  1. Article

    Open Access

    APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation

    The Wnt/β-catenin pathway is critical to maintaining cell fate decisions. Recent study showed that liquid–liquid-phase separation (LLPS) of Axin organized the β-catenin destruction complex condensates in a nor...

    Dan Zhang, Qi-Qi Ni, Shu-Yang Wang, Wen-Feng He… in Cellular and Molecular Life Sciences (2024)

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  2. No Access

    Article

    Circ-sh3rf3/GATA-4/miR-29a regulatory axis in fibroblast–myofibroblast differentiation and myocardial fibrosis

    The transdifferentiation from cardiac fibroblasts to myofibroblasts is an important event in the initiation of cardiac fibrosis. However, the underlying mechanism is not fully understood. Circ-sh3rf3 (circular...

    Cai-**a Ma, Zhi-Ru Wei, Tong Sun, Ming-Hui Yang… in Cellular and Molecular Life Sciences (2023)

  3. No Access

    Article

    ATAT1 regulates forebrain development and stress-induced tubulin hyperacetylation

    α-Tubulin acetyltransferase 1 (ATAT1) catalyzes acetylation of α-tubulin at lysine 40 in various organisms ranging from Tetrahymena to humans. Despite the importance in mammals suggested by studies of cultured ce...

    Lin Li, Sriram Jayabal, Mohammad Ghorbani… in Cellular and Molecular Life Sciences (2019)

  4. No Access

    Article

    Tubulin acetylation: responsible enzymes, biological functions and human diseases

    Microtubules have important functions ranging from maintenance of cell morphology to subcellular transport, cellular signaling, cell migration, and formation of cell polarity. At the organismal level, microtub...

    Lin Li, **ang-Jiao Yang in Cellular and Molecular Life Sciences (2015)