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Inflammatory and Immunomodulatory Effects of Tripterygium wilfordii Multiglycoside in Mouse Models of Psoriasis Keratinocytes

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  1. Article

    Open Access

    XELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial

    Fluoropyrimidine-based combination chemotherapy plus targeted therapy is the standard initial treatment for unresectable metastatic colorectal cancer (mCRC), but the prognosis remains poor. This phase 3 trial ...

    Qiu-Zhong Pan, **g-**g Zhao, Liang Liu in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    ASCL2 induces an immune excluded microenvironment by activating cancer-associated fibroblasts in microsatellite stable colorectal cancer

    Proficient mismatch repair or microsatellite stable (pMMR/MSS) colorectal cancers (CRCs) are vastly outnumbered by deficient mismatch repair or microsatellite instability-high (dMMR/MSI-H) tumors and lack a re...

    Dan Zhang, Qi-Qi Ni, Qiao-Yan Liang, Li-Ling He, Bo-Wen Qiu, Ling-Jie Zhang in Oncogene (2023)

  3. Article

    Open Access

    Clinical characteristics of multicentric reticulohistiocytosis and distinguished features from rheumatoid arthritis: a single-center experience in China

    To investigate the clinical features of multicentric reticulohistiocytosis (MRH).

    **ao-juan Zou, Lin Qiao, Feng Li, Hua Chen in Orphanet Journal of Rare Diseases (2022)

  4. Article

    Open Access

    Glyoxal damages human aortic endothelial cells by perturbing the glutathione, mitochondrial membrane potential, and mitogen-activated protein kinase pathways

    Exposure to glyoxal, the smallest dialdehyde, is associated with several diseases; humans are routinely exposed to glyoxal because of its ubiquitous presence in foods and the environment. The aim of this study...

    Ming-Zhang **e, Chun Guo, Jia-Qi Dong, Jie Zhang in BMC Cardiovascular Disorders (2021)

  5. Article

    Open Access

    Speckle tracking echocardiography in the diagnosis of early left ventricular systolic dysfunction in type II diabetic mice

    The leptin receptor-deficient db/db mouse is a well-established type II diabetes animal model used to investigate diabetic cardiomyopathy. Previous reports have documented diabetic cardiomyopathy is accompanie...

    Rong-juan Li, Jiao Yang, Ya Yang, Ning Ma, Bo Jiang in BMC Cardiovascular Disorders (2014)