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Inflammatory and Immunomodulatory Effects of Tripterygium wilfordii Multiglycoside in Mouse Models of Psoriasis Keratinocytes

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  1. Article

    Open Access

    XELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial

    Fluoropyrimidine-based combination chemotherapy plus targeted therapy is the standard initial treatment for unresectable metastatic colorectal cancer (mCRC), but the prognosis remains poor. This phase 3 trial ...

    Qiu-Zhong Pan, **g-**g Zhao, Liang Liu in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury

    Neutrophils are traditionally viewed as first responders but have a short onset of action in response to traumatic brain injury (TBI). However, the heterogeneity, multifunctionality, and time-dependent modulat...

    Mi Zhou, Yang-Wu-Yue Liu, Yu-Hang He, **g-Yu Zhang, Hao Guo in Military Medical Research (2024)

  3. Article

    Open Access

    Thriving at work as a mediator of the relationship between psychological resilience and the work performance of clinical nurses

    This study aims to investigate the relationship between psychological resilience, thriving at work, and work performance among nurses, as well as analyse the mediating role of thriving at work in the relations...

    Zhou-Min Shen, Yang-Yang Wang, Yi-Min Cai, Ai-Qun Li, Yu-**n Zhang in BMC Nursing (2024)

  4. Article

    Open Access

    ASCL2 induces an immune excluded microenvironment by activating cancer-associated fibroblasts in microsatellite stable colorectal cancer

    Proficient mismatch repair or microsatellite stable (pMMR/MSS) colorectal cancers (CRCs) are vastly outnumbered by deficient mismatch repair or microsatellite instability-high (dMMR/MSI-H) tumors and lack a re...

    Dan Zhang, Qi-Qi Ni, Qiao-Yan Liang, Li-Ling He, Bo-Wen Qiu, Ling-Jie Zhang in Oncogene (2023)

  5. Article

    Open Access

    18F-Florzolotau PET imaging captures the distribution patterns and regional vulnerability of tau pathology in progressive supranuclear palsy

    Human post mortem studies have described the topographical patterns of tau pathology in progressive supranuclear palsy (PSP). Recent advances in tau PET tracers are expected to herald the next era of PSP inves...

    Feng-Tao Liu, Jia-Ying Lu, **n-Yi Li in European Journal of Nuclear Medicine and M… (2023)

  6. Article

    Open Access

    Chemometrics integrated with in silico pharmacology to reveal antioxidative and anti-inflammatory markers of dandelion for its quality control

    Dandelion is an herb with high nutritional and medicinal values, which has been listed in Chinese Pharmacopeia, European Pharmacopoeia and British Pharmacopoeia, gaining increasing acceptance around the world....

    Feng-Jie Liu, Jiao Yang, Xu-Yan Chen, Ting Yu, Hui Ni, Liang Feng in Chinese Medicine (2022)

  7. Article

    Open Access

    GD2-specific chimeric antigen receptor-modified T cells for the treatment of refractory and/or recurrent neuroblastoma in pediatric patients

    This study aimed to evaluate the safety and efficacy of chimeric antigen receptor (CAR) disialoganglioside 2 (GD2)-specific (4SCAR-GD2) T cells for treatment of refractory and/or recurrent neuroblastoma (NB) i...

    Lihua Yu, Lulu Huang, Danna Lin in Journal of Cancer Research and Clinical On… (2022)

  8. Article

    Open Access

    Correction: Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)

    Qian-Qian Yuan, Shu-Yuan **ao, Omar Farouk, Yu-Tang Du in Military Medical Research (2022)

  9. Article

    Open Access

    Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)

    Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care f...

    Qian-Qian Yuan, Shu-Yuan **ao, Omar Farouk, Yu-Tang Du in Military Medical Research (2022)

  10. Article

    Open Access

    Clinical characteristics of multicentric reticulohistiocytosis and distinguished features from rheumatoid arthritis: a single-center experience in China

    To investigate the clinical features of multicentric reticulohistiocytosis (MRH).

    **ao-juan Zou, Lin Qiao, Feng Li, Hua Chen in Orphanet Journal of Rare Diseases (2022)

  11. Article

    Open Access

    Glyoxal damages human aortic endothelial cells by perturbing the glutathione, mitochondrial membrane potential, and mitogen-activated protein kinase pathways

    Exposure to glyoxal, the smallest dialdehyde, is associated with several diseases; humans are routinely exposed to glyoxal because of its ubiquitous presence in foods and the environment. The aim of this study...

    Ming-Zhang **e, Chun Guo, Jia-Qi Dong, Jie Zhang in BMC Cardiovascular Disorders (2021)

  12. Article

    Open Access

    Coronavirus disease 2019 outbreak in Bei**g’s **nfadi Market, China: a modeling study to inform future resurgence response

    A local coronavirus disease 2019 (COVID-19) case confirmed on June 11, 2020 triggered an outbreak in Bei**g, China after 56 consecutive days without a newly confirmed case. Non-pharmaceutical interventions (N...

    **ao-Li Wang, **n Lin, Peng Yang, Zun-You Wu, Gang Li in Infectious Diseases of Poverty (2021)

  13. Article

    Open Access

    Assessment of China’s contributions to the Regional Network for Asian Schistosomiasis and Other Helminth Zoonoses: a questionnaire survey

    The Regional Network for Asian Schistosomiasis and Other Helminth Zoonoses (RNAS+) was established in 1998, which has developed close partnerships with Asian countries endemic for schistosomiasis and other helmin...

    Hong-Mei Li, Ying-Jun Qian, Kun Yang, Wei Ding in Global Health Research and Policy (2021)

  14. Article

    Open Access

    Application of Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) in hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver, and its morbidity and mortality have been increasing in recent years. The early diagnosis and prompt treatment of small HCC are c...

    Xue-Qin Li, **ng Wang, Da-Wei Zhao, Jun Sun in World Journal of Surgical Oncology (2020)

  15. Article

    Open Access

    Water extract from processed Polygonum multiflorum modulate gut microbiota and glucose metabolism on insulin resistant rats

    The incidence of insulin resistance (IR) has rapidly increased worldwide over the last 20 years, no perfect solution has yet been identified. Finding new therapeutic drugs will help improve this situation. As ...

    Wen Gu, Min Yang, Qian Bi, Lin-** Zeng, ** Wang in BMC Complementary Medicine and Therapies (2020)

  16. Article

    Open Access

    Effects of an abnormal mini-mental state examination score on postoperative outcomes in geriatric surgical patients: a meta-analysis

    Perioperative cognitive impairment (CI) following surgeries is prevalent in geriatric surgical population aged 60 and older. This meta-analysis was designed to investigate whether the Mini-Mental State Examina...

    Shuang-jiao Cao, Dongxu- Chen, Lei Yang, Tao Zhu in BMC Anesthesiology (2019)

  17. Article

    Open Access

    Macular evaluation of the retinal and choroidal vasculature changes in anterior ischemic optic neuropathy-a case control study

    This study aimes to characterize the fundus structural changes in patients with nonarteritic anterior ischemic optic neuropathy (NAION) and the correlation between macular vessel density, retinal nerve fibre l...

    Hui Wang, Zhao-yang Meng, Song-guo Li, **g-**g Wang, Jiao Sun in BMC Ophthalmology (2018)

  18. Article

    Open Access

    World Congress Integrative Medicine & Health 2017: part two

    Carolyn Ee, Sharmala Thuraisingam in BMC Complementary and Alternative Medicine (2017)

  19. Article

    Open Access

    Speckle tracking echocardiography in the diagnosis of early left ventricular systolic dysfunction in type II diabetic mice

    The leptin receptor-deficient db/db mouse is a well-established type II diabetes animal model used to investigate diabetic cardiomyopathy. Previous reports have documented diabetic cardiomyopathy is accompanie...

    Rong-juan Li, Jiao Yang, Ya Yang, Ning Ma, Bo Jiang in BMC Cardiovascular Disorders (2014)