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  1. Article

    Open Access

    Modified craniotomy procedures and virtual reality technology for accurate localization of the frontal branch of MMA in revascularization surgery

    The frontal branch of middle meningeal artery (MMA) can easily be damaged during revascularization surgery. To precise locate it and minimize its injury, we propose a set of modified craniotomy procedures comb...

    Liu Chuang-Hong, Xu Hong, Kong Gang in Scientific Reports (2024)

  2. Article

    Open Access

    A bioinspired surface tension-driven route toward programmed cellular ceramics

    The intriguing biomineralization process in nature endows the mineralized biological materials with intricate microarchitected structures in a facile and orderly way, which provides an inspiration for processi...

    Ying Hong, Shiyuan Liu, **aodan Yang, Wang Hong, Yao Shan in Nature Communications (2024)

  3. Article

    Open Access

    Molecular fingerprinting of biological nanoparticles with a label-free optofluidic platform

    Label-free detection of multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free...

    Alexia Stollmann, Jose Garcia-Guirado, Jae-Sang Hong, Pascal Rüedi in Nature Communications (2024)

  4. Article

    Open Access

    Clinical characteristics and removal approaches of tracheal and bronchial foreign bodies in elders

    The symptoms of tracheobronchial foreign body in the elderly are not typical, so they are often missed or misdiagnosed. This study aims to depict the clinical characteristics of tracheobronchial foreign body i...

    **-Yang Hong, Ling Wang, Yan-** Du, Miao Wang, Yi-Yuan Chen in Scientific Reports (2024)

  5. Article

    Open Access

    Automated analysis of knee joint alignment using detailed angular values in long leg radiographs based on deep learning

    Malalignment in the lower limb structure occurs due to various causes. Accurately evaluating limb alignment in situations where malalignment needs correction is necessary. To create an automated support system...

    Hong Seon Lee, Sangchul Hwang, Sung-Hwan Kim, Nam Bum Joon in Scientific Reports (2024)

  6. Article

    Open Access

    Increased monocytic myeloid-derived suppressor cells in type 2 diabetes correlate with hyperglycemic and was a risk factor of infection and tumor occurrence

    To investigate the frequency of monocytic myeloid-derived suppressor cells (M-MDSCs) in type 2 diabetes mellitus (T2DM) patients and explore the potential associations between M-MDSCs, glycemic control, and th...

    Ji Zhou, Mengjie Zhang, **aodi Ju, Hui** Wang, Hao **ao in Scientific Reports (2024)

  7. Article

    Open Access

    A multicenter clinical AI system study for detection and diagnosis of focal liver lesions

    Early and accurate diagnosis of focal liver lesions is crucial for effective treatment and prognosis. We developed and validated a fully automated diagnostic system named Liver Artificial Intelligence Diagnosi...

    Hanning Ying, **aoqing Liu, Min Zhang, Yiyue Ren, Shihui Zhen in Nature Communications (2024)

  8. Article

    Open Access

    Gankyrin inhibits ferroptosis through the p53/SLC7A11/GPX4 axis in triple-negative breast cancer cells

    Gankyrin is found in high levels in triple-negative breast cancer (TNBC) and has been established to form a complex with the E3 ubiquitin ligase MDM2 and p53, resulting in the degradation of p53 in hepatocarci...

    Ming Lei, Yun-Long Zhang, Feng-Ying Huang, Heng-Yu Chen in Scientific Reports (2023)

  9. Article

    Open Access

    Construction of Streptomyces coelicolor A3(2) mutants that exclusively produce NA4/NA6 intermediates of agarose metabolism through mutation induction

    NA4/NA6, an intermediate degradation product of β-agarase, is a high value-added product with anticancer, anti-obesity, and anti-diabetic effects. Therefore, a method that enables the efficient production of N...

    **a Kim, Eun Joo Kim, Hye-Jeong Ko, Yeon-Hee Lee, Soon-Kwang Hong in Scientific Reports (2023)

  10. Article

    Open Access

    Elucidating the molecular mechanisms underlying anti-inflammatory effects of Morchella esculenta in the arachidonic acid metabolic pathway by network pharmacology and molecular docking

    Morchella esculenta is an edible fungus with a uniquely delicious flavor and remarkable benefits for health. Herein, the molecular mechanism underlying the anti-inflammatory effects of Morchella esculenta was elu...

    Ma **aoying, Huo Zhiming, Yang Tao, **ao Jun, Zhao Ying, Gong Na in Scientific Reports (2023)

  11. Article

    Open Access

    Training certified detectives to track down the intrinsic shortcuts in COVID-19 chest x-ray data sets

    Deep learning faces a significant challenge wherein the trained models often underperform when used with external test data sets. This issue has been attributed to spurious correlations between irrelevant feat...

    Ran Zhang, Dalton Griner, John W. Garrett, Zhihua Qi, Guang-Hong Chen in Scientific Reports (2023)

  12. Article

    Open Access

    Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons

    Immunotherapy has become established as major treatment modality for multiple types of solid tumors, including colorectal cancer. Identifying novel immunotherapeutic targets to enhance anti-tumor immunity and ...

    Yanan Liu, Longmiao Hu, Zhengzhen Wu, Kun Yuan, Guangliang Hong in Nature Communications (2023)

  13. Article

    Open Access

    Zero-determinant strategy in stochastic Stackelberg asymmetric security game

    In a stochastic Stackelberg asymmetric security game, the strong Stackelberg equilibrium (SSE) strategy is a popular option for the defender to get the highest utility against an attacker with the best respons...

    Zhaoyang Cheng, Guanpu Chen, Yiguang Hong in Scientific Reports (2023)

  14. Article

    Open Access

    Short-term impact of diurnal temperature range on cardiovascular diseases mortality in residents in northeast China

    It has been reported that cardiovascular disease (CVD) has become one of the major threats to global public health and is associated with climate change. Several previous studies have shown the influence of am...

    Xuan Kai, Zhimin Hong, Yang Hong, **aolei Wang, Chunyang Li in Scientific Reports (2023)

  15. Article

    Open Access

    Polar Solomon rings in ferroelectric nanocrystals

    Solomon rings, upholding the symbol of wisdom with profound historical roots, were widely used as decorations in ancient architecture and clothing. However, it was only recently discovered that such topologica...

    **g Wang, Deshan Liang, **g Ma, Yuanyuan Fan, Ji Ma in Nature Communications (2023)

  16. Article

    Open Access

    TRIM5α recruits HDAC1 to p50 and Sp1 and promotes H3K9 deacetylation at the HIV-1 LTR

    Tripartite motif-containing protein 5α (TRIM5α) is generally known to block the postentry events of HIV-1. Here, we report an uncharacterized role for TRIM5α in the maintenance of viral latency. Knockdown of T...

    **ang-Hong Ran, Jia-Wu Zhu, Run-Ze Ni, Yong-Tang Zheng in Nature Communications (2023)

  17. Article

    Open Access

    Elevated serum uric acid is associated with infertility in women living in America

    Excessive uric acid levels may affect several organs and systems in the body. There is limited evidence of the effects of high serum uric acid levels on the female reproductive system. This study used the Nati...

    **ang Hong, Fanqi Zhao, Wei Wang, **gying Wu, **aoqi Zhu, Bei Wang in Scientific Reports (2023)

  18. Article

    Open Access

    CEA dynamics for predicting response after anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer

    Carcinoembryonic antigen (CEA) is the most widely used tumor marker in metastatic colorectal cancer (mCRC). However, its potential as a predictive marker of progression in mCRC during systemic chemotherapy, pa...

    Sora Kang, Sun Young Kim, Yong Sang Hong, Tae Won Kim, Ki Eun Choi in Scientific Reports (2023)

  19. Article

    Open Access

    Observation of structural switch in nascent SAM-VI riboswitch during transcription at single-nucleotide and single-molecule resolution

    Growing RNAs fold differently as they are transcribed, which modulates their finally adopted structures. Riboswitches regulate gene expression by structural change, which are sensitive to co-transcriptionally ...

    Yanyan Xue, Jun Li, Dian Chen, **zhu Zhao, Liang Hong, Yu Liu in Nature Communications (2023)

  20. Article

    Open Access

    Well-defined double hysteresis loop in NaNbO3 antiferroelectrics

    Antiferroelectrics (AFEs) are promising candidates in energy-storage capacitors, electrocaloric solid-cooling, and displacement transducers. As an actively studied lead-free antiferroelectric (AFE) material, N...

    Nengneng Luo, Li Ma, Gengguang Luo, Chao Xu, Lixiang Rao in Nature Communications (2023)

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