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Article
Fruquintinib plus paclitaxel versus placebo plus paclitaxel for gastric or gastroesophageal junction adenocarcinoma: the randomized phase 3 FRUTIGA trial
The vascular endothelial growth factor pathway plays a key role in the pathogenesis of gastric cancer. In the multicenter, double-blind phase 3 FRUTIGA trial, 703 patients with advanced gastric or gastroesopha...
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Article
Open AccessEfficacy and safety of surufatinib plus toripalimab, a chemotherapy-free regimen, in patients with advanced gastric/gastroesophageal junction adenocarcinoma, esophageal squamous cell carcinoma, or biliary tract cancer
The programmed death 1 inhibitor toripalimab plus the angio-immuno kinase inhibitor surufatinib showed a tolerable safety profile and preliminary efficacy in patients with advanced solid tumors in a phase I st...
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Article
Feasibility of Injecting Pretreated Mine Water into a Deep Ordovician Aquifer in the Lilou Coal Mine, China
The groundwater quality in the Lilou Coal Mine in Shandong Province can be divided into “three zones” based on the range of mining-induced fractures. Considering the observed Ordovician aquifer water level dec...
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Article
Open AccessResearch on permanent magnet synchronous motor algorithm based on linear nonlinear switching self-disturbance rejection control
This paper presents a linear-nonlinear switching control strategy, called Switching Active Disturbance Rejection Control (SADRC), to enhance the disturbance rejection capability of the speed controller in a se...
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Article
Global and regional controls on carbon-sulfur isotope cycling during SPICE event in south China
The positive S-isotopic excursion of carbonate-associated sulfate (δ34SCAS) is generally in phase with the Steptoean positive carbon isotope excursion (SPICE), which may reflect widespread, global, transient incr...
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Article
Open AccessWWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT
WWC1 regulates episodic learning and memory, and genetic nucleotide polymorphism of WWC1 is associated with neurodegenerative diseases such as Alzheimer’s disease. However, the molecular mechanism through which W...
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Article
Competitive adsorption of lead and cadmium onto nanoplastics with different charges: Two-dimensional correlation spectroscopy study
The competitive adsorption ability and mechanisms of lead (Pb2+) and cadmium (Cd2+) by nanoplastics (NPs) with positive charges (PS-NH2) and negative charges (PS-SO3H) were investigated by using batch adsorption ...
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Chapter and Conference Paper
Cold & Warm Net: Addressing Cold-Start Users in Recommender Systems
Cold-start recommendation is one of the major challenges faced by recommender systems (RS). Herein, we focus on the user cold-start problem. Recently, methods utilizing side information or meta-learning have b...
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Article
Open AccessRare ectopic thyroid tissue as multiple bilateral pulmonary nodules: a case report and literature review
The prevalence of ectopic thyroid tissue is 1 in every 100,000 to 300,000 persons in the general population, and ectopic thyroid tissue in the bilateral lung lobes is even rarer. Due to its rarity, there is no...
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Article
Bone marrow mesenchymal stem cells-derived exosomes containing miR-539-5p inhibit pyroptosis through NLRP3/caspase-1 signalling to alleviate inflammatory bowel disease
Exosomes derived from bone mesenchymal stem cells (BMSCs) are potential candidates for inflammatory bowel disease (IBD) treatment. The present study investigated the therapeutic effect and potential mechanism ...
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Article
Retraction Note: microRNA-211-mediated targeting of the INHBA-TGF-β axis suppresses prostate tumor formation and growth
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Article
An Analog Model Study on Water–Sand Mixture Inrush Mechanisms During the Mining of Shallow Coal Seams
Water–sand mixture inrushes into shallow underground workings have caused casualties and property loss. A coupled fluid–solid analog model was developed to simulate the water–sand mixture inrush processes duri...
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Article
Open AccessDevelopment and validation of the psoriasis scale among the system of quality of life instruments for chronic diseases QLICD-PS (V2.0)
Psoriasis (PS) is difficult to cure with a high incidence. Therefore, the quality of life (QOL) of people with Psoriasis has caused widespread concern. Universal scales respond poorly to subtle changes caused ...
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Article
Environmental impact assessment of ground source heat pump system for heating and cooling: a case study in China
Ground source heat pump (GSHP) utilizes shallow geothermal energy to meet the heating and cooling needs of buildings. It has drawn global attention owing to its environmental friendliness and high energy effic...
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Article
Applying the Tilt-depth and Tilt-Euler techniques of gravity data to decipher the basement depth in Sichuan Basin, China
The tilt angle (i.e., TDR) provides an efficient way to recognize the horizontal locations of multi-source geological bodies at different depths and inclination angles. The tilt-depth method was initially deri...
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Article
RETRACTED ARTICLE: microRNA-211-mediated targeting of the INHBA-TGF-β axis suppresses prostate tumor formation and growth
Prostate cancer (PCa) stem cells increase the sustainability of tumor growth, resulting in high relapse rates in patients with PCa. This goal of the present study was to elucidate the function of microRNA (miR...
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Article
Open AccessUndergraduate students’ norms for the Chinese version of the symptom check-List-90-R (SCL-90-R)
Despite widespread application of the Symptom Check-List-90-R (SCL-90-R) for Chinese undergraduate students, there are no appropriate norms for them. The aim of this study is to provide norms for the Chinese v...
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Article
Open AccessHealth related quality of life in patients with chronic gastritis and peptic ulcer and factors with impact: a longitudinal study
The assessment of Health Related Quality of Life (HRQOL) has been applied as a significant outcome indicator for patients with chronic diseases. No HRQOL study, however, has looked at HRQOL in patients with ch...
