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  1. No Access

    Article

    The association between cardiac T2*BOLD and quantitative flow ratio (QFR) in the diagnosis of stenotic coronary arteries in patients with multi-vessel coronary artery disease

    T2*BOLD is based on myocardial deoxyhemoglobin content to reflect the state of myocardial oxygenation. Quantitative flow ratio is a tool for assessing coronary blood flow based on invasive coronary angiography.

    Lei Zhao, Bing-Hua Chen, Hui Tang, Yong-Yi Wang, Zi-Yi Gu in La radiologia medica (2024)

  2. Article

    Open Access

    Adverse postoperative outcomes in elderly patients with sarcopenia

    No study has compared 30-day and 90-day adverse postoperative outcomes between old-age patients with and those without sarcopenia.

    Yitian Yang, Mingyang Sun, Wan-Ming Chen, Szu-Yuan Wu, Jiaqiang Zhang in BMC Geriatrics (2024)

  3. Article

    Open Access

    Understanding and alleviating informal caregiver burden through the development and validation of a caregiver strain index-based model in Taiwan

    Quantifying the informal caregiver burden is important for understanding the risk factors associated with caregiver overload and for evaluating the effectiveness of services provided in Long-term Care (LTC).

    Shuo-Chen Chien, Yu-Hung Chang, Chia-Ming Yen, Ying-Erh Chen in BMC Geriatrics (2024)

  4. Article

    Open Access

    Which factors are associated with adverse prognosis in multiple myeloma patients after surgery? - preliminary establishment and validation of the nomogram

    To investigate the prognosis of patients with Multiple Myeloma (MM) after surgery, analyze the risk factors leading to adverse postoperative outcomes, and establish a nomogram.

    Jun-Peng Liu, Zi-Yu Xu, Yue Wu, **ang-Jun Shi in World Journal of Surgical Oncology (2024)

  5. Article

    Open Access

    Fractal analysis of left ventricular trabeculae in heart failure with preserved ejection fraction patients with multivessel coronary artery disease

    Endocardial trabeculae undergo varicose changes and hyperplasia in response to hemodynamic influences and are a variable phenotype reflecting changes in disease. Fractal analysis has been used to analyze the c...

    Zi-Yi Gu, Bing-Hua Chen, Lei Zhao, Dong-Aolei An, Chong-Wen Wu in Insights into Imaging (2024)

  6. Article

    Open Access

    Ceftazidime/avibactam versus polymyxin B in carbapenem-resistant Klebsiella pneumoniae infections: a propensity score-matched multicenter real-world study

    In this retrospective observational multicenter study, we aimed to assess efficacy and mortality between ceftazidime/avibactam (CAZ/AVI) or polymyxin B (PMB)-based regimens for the treatment of Carbapenem-resi...

    Hai-Hui Zhuang, Qiang Qu, Wen-Ming Long, Qin Hu, **ao-Li Wu, Ying Chen in Infection (2024)

  7. Article

    Open Access

    USP47 deficiency in mice modulates tumor infiltrating immune cells and enhances antitumor immune responses in prostate cancer

    This study investigates the role of USP47, a deubiquitinating enzyme, in the tumor microenvironment and its impact on antitumor immune responses. Analysis of TCGA database revealed distinct expression patterns...

    Qian-Lan Wang, Shun-Yuan Lu, Dan-Dan Xu, **-**a Ma in Cancer Immunology, Immunotherapy (2024)

  8. No Access

    Article

    Clinical Value of the Quantitative Flow Ratio to Predict Long-term Target Vessel Failure in Patients with In-stent Restenosis after Drug-coated Balloon Angioplasty

    The study sought to investigate the clinical predictive value of quantitative flow ratio (QFR) for the long-term target vessel failure (TVF) outcome in patients with in-stent restenosis (ISR) by using drug-coa...

    **ang-qi Wu, Long-bo Li, Wei You, Zhi-ming Wu, Lei Zhao in Current Medical Science (2024)

  9. Article

    Open Access

    A multicenter prospective study on the management of hepatoblastoma in children: a report from the Chinese Children’s Cancer Group

    This study aimed to identify survival risk factors in Chinese children with hepatoblastoma (HB) and assess the effectiveness of the new treatment protocol proposed by the Chinese Children’s Cancer Group (CCCG)...

    Meng-Jie Tang, **ao-Li Ma, **ang-Ling He, Wei-Hua Pan in World Journal of Pediatrics (2024)

  10. Article

    Open Access

    Physical frailty, genetic predisposition, and incident dementia: a large prospective cohort study

    Physical frailty and genetic factors are both risk factors for increased dementia; nevertheless, the joint effect remains unclear. This study aimed to investigated the long-term relationship between physical f...

    Pei-Yang Gao, Ling-Zhi Ma, Xue-Jie Wang, Bang-Sheng Wu in Translational Psychiatry (2024)

  11. Article

    Open Access

    Assessing mortality risk in Type 2 Diabetes patients with prolonged ASCVD risk factors: the inclusive Poh-Ai predictive scoring system with CAC Score integration

    To enhance the predictive risk model for all-cause mortality in individuals with Type 2 Diabetes (T2DM) and prolonged Atherosclerotic Cardiovascular Disease (ASCVD) risk factors. Despite the utility of the Cor...

    Meng-Huan Lei, Yu-Chen Hsu, Sheng-Liang Chung in Diabetology & Metabolic Syndrome (2024)

  12. Article

    Open Access

    Sex difference in the associations among risk factors with gastroesophageal reflux disease in a large Taiwanese population study

    Gastroesophageal reflux disease (GERD) is a common global health issue. Previous studies have revealed a higher prevalence of GERD in females than in males, however few studies have investigated sex difference...

    Chien-Chieh Lin, Jiun-Hung Geng, Pei-Yu Wu, Jiun-Chi Huang in BMC Gastroenterology (2024)

  13. No Access

    Article

    Acetylcholine muscarinic M1 receptors in the rodent prefrontal cortex modulate cognitive abilities to establish social hierarchy

    In most social species, the attainment of social dominance is strongly affected by personality traits. Dominant individuals show better cognitive abilities, however, whether an individual’s cognition can deter...

    Wen-Jun Chen, Hao Chen, Zi-Ming Li, Wei-Yuan Huang, Jian-Lin Wu in Neuropsychopharmacology (2024)

  14. Article

    Open Access

    Adequate antiviral treatment lowers overall complications of cytomegalovirus colitis among inpatients with inflammatory bowel diseases

    Cytomegalovirus (CMV) colitis significantly complicates the course of inflammatory bowel disease (IBD), frequently leading to severe flare-ups and poor outcomes. The role of antiviral therapy in hospitalized I...

    Ching-Reigh Hsieh, Ren-Chin Wu, Chia-Jung Kuo, Pai-Jui Yeh in BMC Infectious Diseases (2024)

  15. Article

    Open Access

    Fractal analysis of left ventricular trabeculae in post-STEMI: from acute to chronic phase

    The temporal evolution of ventricular trabecular complexity and its correlation with major adverse cardiovascular events (MACE) remain indeterminate in patients presenting with acute ST elevation myocardial in...

    Ruo-Yang Shi, Rui Wu, **jun Ran, Lang-Lang Tang, Luke Wesemann in Insights into Imaging (2024)

  16. Article

    Open Access

    A case report of drug interaction between co-packaged nirmatrelvir-ritonavir and tacrolimus causing hyponatremia in a lung transplant recipient

    Coronavirus disease 2019 (COVID-19) infection in lung transplant recipients can be lethal owing to the use of immunosuppressants. Antiviral agents may be administered to these patients. Co-packaged nirmatrelvi...

    Chien-Ming Lo, Wei-Hsun Chen, Meng-Yun Tsai, Hung-I Lu in Journal of Cardiothoracic Surgery (2024)

  17. No Access

    Article

    Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy: A Multicenter Double-Blind Randomized Controlled Trial

    To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction (TW) in treating patients with diabetic peripheral neuropathy (DPN).

    Hao-yue Huang, Yu-** Lin, Hua Wei, Yu Fu in Chinese Journal of Integrative Medicine (2024)

  18. Article

    Open Access

    Prognostic value of right atrial strains in arrhythmogenic right ventricular cardiomyopathy

    Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy characterized by progressive fibrofatty infiltration of atrial and ventricular myocardium resulting in adverse cardiac even...

    **-Yu Zheng, Bing-Hua Chen, Rui Wu, Dong-Aolei An, Ruo-Yang Shi in Insights into Imaging (2024)

  19. Article

    Open Access

    Impact of preoperative factors and waiting time on post-appendectomy complications: a retrospective study

    Several factors are associated with increased postoperative complications after appendectomies. However, few studies combined these potential factors for comprehensive prediction of surgical outcomes. Whether ...

    Shuo-Lun Lai, Chin-Hao Chang, Po-Chu Lee, Cheng-Maw Ho in Perioperative Medicine (2024)

  20. Article

    Open Access

    SGLT2i relieve proteinuria in diabetic nephropathy patients potentially by inhibiting renal oxidative stress rather than through AGEs pathway

    To estimate the effects of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) on proteinuria and oxidative stress expression in type 2 diabetes patients.

    **ao-chun Zeng, Yuan Tian, **an-ming Liang, **ao-bin Wu in Diabetology & Metabolic Syndrome (2024)

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