37 Result(s)

Article

IGF2BP2 and obesity interaction analysis for type 2 diabetes mellitus in Chinese Han population

The objective of this study was to systematically evaluate the contribution of the insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) to type 2 diabetes mellitus (T2DM) and its interaction with obesity...

Hui-Hui Wu, Nai-Jia Liu, Zhen Yang, **ao-Ming Tao… in European Journal of Medical Research (2014)

Article

An analysis of the association between a polymorphism of KCNJ11 and diabetic retinopathy in a Chinese Han population

Genome-wide association studies (GWAS) have reported that the polymorphism rs5219 of the potassium inwardly rectifying channel, subfamily J, member 11 (KCNJ11) is associated with type 2 diabetes mellitus (T2DM). ...

Nai-Jia Liu, Hui-Hui Wu, Yan-Liang Li, Zhen Yang… in European Journal of Medical Research (2015)

Article

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Andreas Lundqvist, Vincent van Hoef, **aonan Zhang… in Journal for ImmunoTherapy of Cancer (2016)

Article

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Casey Ager, Matthew Reilley, Courtney Nicholas… in Journal for ImmunoTherapy of Cancer (2016)

Article

Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

Haploidentical donor (HID) hematopoietic stem cell transplantation (HSCT) is an alternative treatment method for severe aplastic anemia (SAA) patients lacking suitable identical donors and those who are refrac...

Lan-** Xu, Song **, Shun-Qing Wang, Ling-Hui **a… in Journal of Hematology & Oncology (2017)

Article

Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

An increased expression of Yes-associated protein (YAP1) has been shown to promote tumorigenesis in many cancer types including colon. However, the role of YAP1 in promoting colon tumorigenesis remains unclear...

Yan-Jiun Huang, Ching-Kuo Yang, Po-Li Wei… in Journal of Hematology & Oncology (2017)

Article

Cervical squamous cell carcinoma-secreted exosomal miR-221-3p promotes lymphangiogenesis and lymphatic metastasis by targeting VASH1

Cancer-secreted exosomal miRNAs are emerging mediators of cancer-stromal cross-talk in the tumor environment. Our previous miRNAs array of cervical squamous cell carcinoma (CSCC) clinical specimens identified ...

Chen-Fei Zhou, **g Ma, Lei Huang, Hong-Yan Yi, Yan-Mei Zhang, **ang-Guang Wu… in Oncogene (2019)

Article

Therapeutic efficacy, pharmacokinetic profiles, and toxicological activities of humanized antibody-drug conjugate Zt/g4-MMAE targeting RON receptor tyrosine kinase for cancer therapy

Aberrant expression of the RON receptor tyrosine kinase is a pathogenic feature and a validated drug target in various types of cancers. Currently, therapeutic antibodies targeting RON for cancer therapy are u...

Hang-** Yao, Liang Feng, Sreedhar Reddy Suthe… in Journal for ImmunoTherapy of Cancer (2019)

Article

Texture analysis of pretreatment [¹⁸F]FDG PET/CT for the prognostic prediction of locally advanced salivary gland carcinoma treated with interstitial brachytherapy

The aim of this study was to evaluate the prognostic value of positron emission tomography (PET) parameters and the PET texture features of fluorine 18-fluorodeoxyglucose ([¹⁸F]FDG) uptake on pretreatment PET/com...

Wen-Jie Wu, Zhen-Yu Li, Shuang Dong, Shu-Ming Liu, Lei Zheng… in EJNMMI Research (2019)

Article

CT radiomic features for predicting resectability of oesophageal squamous cell carcinoma as given by feature analysis: a case control study

Computed tomography (CT) is commonly used in all stages of oesophageal squamous cell carcinoma (SCC) management. Compared to basic CT features, CT radiomic features can objectively obtain more information abou...

**g Ou, Rui Li, Rui Zeng, Chang-qiang Wu, Yong Chen, Tian-wu Chen… in Cancer Imaging (2019)

Article

Alteration in TET1 as potential biomarker for immune checkpoint blockade in multiple cancers

Immune checkpoint inhibitors (ICIs) have achieved impressive success in different cancer types, yet responses vary and predictive biomarkers are urgently needed. Growing evidence points to a link between DNA m...

Hao-**ang Wu, Yan-**ng Chen, Zi-**an Wang, Qi Zhao… in Journal for ImmunoTherapy of Cancer (2019)

Article

M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

Long non-coding RNAs (lncRNAs) possess significant regulatory functions in multiple biological and pathological processes, especially in cancer. Dysregulated lncRNAs in hepatocellular carcinoma (HCC) and their...

Xueliang Zuo, Zhiqiang Chen, Wen Gao, Yao Zhang… in Journal of Hematology & Oncology (2020)

Article

A Delta-radiomics model for preoperative evaluation of Neoadjuvant chemotherapy response in high-grade osteosarcoma

The difficulty of assessment of neoadjuvant chemotherapeutic response preoperatively may hinder personalized-medicine strategies that depend on the results from pathological examination.

Peng Lin, Peng-Fei Yang, Shi Chen, You-You Shao, Lei Xu, Yan Wu… in Cancer Imaging (2020)

Article

Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer

Expression of Oct4 maintains cancer stem cell (CSC)-like properties in lung cancer cells and is correlated with poor prognosis of lung adenocarcinoma. M2-type tumor-associated macrophages (TAMs) promote cancer...

Chia-Sing Lu, Ai-Li Shiau, Bing-Hua Su, Tsui-Shan Hsu… in Journal of Hematology & Oncology (2020)

Article

Validation of nomogram-revised risk index and comparison with other models for extranodal nasal-type NK/T-cell lymphoma in the modern chemotherapy era: indication for prognostication and clinical decision-making

Derived from our original nomogram study by using the risk variables from multivariable analyses in the derivation cohort of 1383 patients with extranodal NK/T-cell lymphoma, nasal-type (ENKTCL) who were mostl...

Si-Ye Chen, Yong Yang, Shu-Nan Qi, Ying Wang, Chen Hu, **a He, Li-Ling Zhang… in Leukemia (2021)

Article

Reappraise role of No. 10 lymphadenectomy for proximal gastric cancer in the era of minimal invasive surgery during total gastrectomy: a pooled analysis of 4 prospective trial

For patients with locally advanced proximal gastric cancer (LAPGC), the individualized selection of patients with highly suspected splenic hilar (No. 10) lymph node (LN) metastasis to undergo splenic hilar lym...

Qing Zhong, Qi-Yue Chen, Yan-Chang Xu, Gang Zhao, Li-Sheng Cai… in Gastric Cancer (2021)

Article

Targeting autophagy as a therapeutic strategy for identification of liganans from Peristrophe japonica in Parkinson’s disease

An-Guo Wu, Rong Pan, Betty Yuen-Kwan Law… in Signal Transduction and Targeted Therapy (2021)

Article

The M1/M2 spectrum and plasticity of malignant pleural effusion-macrophage in advanced lung cancer

Malignant pleural effusion (MPE)-macrophage (Mφ) of lung cancer patients within unique M1/M2 spectrum showed plasticity in M1–M2 transition. The M1/M2 features of MPE-Mφ and their significance to patient outco...

Ming-Fang Wu, Chih-An Lin, Tzu-Hang Yuan… in Cancer Immunology, Immunotherapy (2021)

Article

Small molecules in targeted cancer therapy: advances, challenges, and future perspectives

Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs, targeted therapeutic drugs have become mainstream cancer treatments. Since the first tyrosine kinase inhibitor imatini...

Lei Zhong, Yueshan Li, Liang **ong… in Signal Transduction and Targeted Therapy (2021)

Article

Clinical characteristics and immunological abnormalities of Castleman disease complicated with autoimmune diseases

To explore the clinical features and immunological mechanisms of Castleman disease (CD) complicated with autoimmune diseases (AID).

Dao-** Sun, Wen-Ming Chen, Li Wang… in Journal of Cancer Research and Clinical On… (2021)