1,564 Result(s)
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**an-ming Wu
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Article
One-Pot Template-Free Synthesis of Mesoporous ZnCo2O4 Microbubbles for Oxygen Evolution Reaction
Spinel ZnCo2O4 is an important multi-functional material with wide applications, such as electrocatalytic oxygen evolution reaction. However, it still remains a challenge to synthesize ZnCo2O4 with complex morpho...
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Raddeanin A Protects the BRB Through Inhibiting Inflammation and Apoptosis in the Retina of Alzheimer’s Disease
Neuroinflammation and endothelial cell apoptosis are prominent features of blood–brain barrier (BBB) disruption, which have been described in Alzheimer’s disease (AD) and can predict cognitive decline. Recent ...
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Open AccessAsymmetric total synthesis of polycyclic xanthenes and discovery of a WalK activator active against MRSA
The development of new antibiotics continues to pose challenges, particularly considering the growing threat of multidrug-resistant Staphylococcus aureus. Structurally diverse natural products provide a promising...
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The association between cardiac T2*BOLD and quantitative flow ratio (QFR) in the diagnosis of stenotic coronary arteries in patients with multi-vessel coronary artery disease
T2*BOLD is based on myocardial deoxyhemoglobin content to reflect the state of myocardial oxygenation. Quantitative flow ratio is a tool for assessing coronary blood flow based on invasive coronary angiography.
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Analysis of dominant phases inhibiting dissociation of smelting slags and the alkali depolymerization mechanism
This study analyzed the prevalent physicochemical phases of smelting slag from the perspective of data science and chemistry. Findings delineated the silicate phase as the pivotal and predominant constraining ...
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Open AccessUnraveling the energy storage mechanism in graphene-based nonaqueous electrochemical capacitors by gap-enhanced Raman spectroscopy
Graphene has been extensively utilized as an electrode material for nonaqueous electrochemical capacitors. However, a comprehensive understanding of the charging mechanism and ion arrangement at the graphene/e...
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Open AccessDesigning a highly efficient type III polyketide whole-cell catalyst with minimized byproduct formation
Polyketide synthases (PKSs) are classified into three types based on their enzyme structures. Among them, type III PKSs, catalyzing the iterative condensation of malonyl-coenzyme A (CoA) with a CoA-linked star...
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Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
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Article
SnO2/metal organic complex composite derived from low-temperature activated metal organic complex for advanced lithium storage
Sn-based metal organic complexes with coordination bonds, multi-active sites, and high theoretical capacity have attracted much attention as promising anodes for lithium ion batteries. However, the low electri...
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Article
Open AccessAdverse postoperative outcomes in elderly patients with sarcopenia
No study has compared 30-day and 90-day adverse postoperative outcomes between old-age patients with and those without sarcopenia.
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Open AccessUnderstanding and alleviating informal caregiver burden through the development and validation of a caregiver strain index-based model in Taiwan
Quantifying the informal caregiver burden is important for understanding the risk factors associated with caregiver overload and for evaluating the effectiveness of services provided in Long-term Care (LTC).
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Article
Open AccessWhich factors are associated with adverse prognosis in multiple myeloma patients after surgery? - preliminary establishment and validation of the nomogram
To investigate the prognosis of patients with Multiple Myeloma (MM) after surgery, analyze the risk factors leading to adverse postoperative outcomes, and establish a nomogram.
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Open AccessFractal analysis of left ventricular trabeculae in heart failure with preserved ejection fraction patients with multivessel coronary artery disease
Endocardial trabeculae undergo varicose changes and hyperplasia in response to hemodynamic influences and are a variable phenotype reflecting changes in disease. Fractal analysis has been used to analyze the c...
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Open AccessCeftazidime/avibactam versus polymyxin B in carbapenem-resistant Klebsiella pneumoniae infections: a propensity score-matched multicenter real-world study
In this retrospective observational multicenter study, we aimed to assess efficacy and mortality between ceftazidime/avibactam (CAZ/AVI) or polymyxin B (PMB)-based regimens for the treatment of Carbapenem-resi...
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Open AccessGut microbiota-derived acetate attenuates lung injury induced by influenza infection via protecting airway tight junctions
Gut microbiota (GM) have been implicated as important regulators of gastrointestinal symptom which is commonly occurred along with respiratory influenza A virus (IAV) infection, suggesting the involvement of t...
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Open AccessA Cysteinyl-tRNA Synthetase Mutation Causes Novel Autosomal-Dominant Inheritance of a Parkinsonism/Spinocerebellar-Ataxia Complex
This study aimed to identify possible pathogenic genes in a 90-member family with a rare combination of multiple neurodegenerative disease phenotypes, which has not been depicted by the known neurodegenerative...
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Open AccessGD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior
While better management of loco-regional prostate cancer (PC) has greatly improved survival, advanced PC remains a major cause of cancer deaths. Identification of novel targetable pathways that contribute to t...
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Article
T cell-redirecting antibody for treatment of solid tumors via targeting mesothelin
T cell engaging bispecific antibodies (TCBs) have recently become significant in cancer treatment. In this study we developed MSLN490, a novel TCB designed to target mesothelin (MSLN), a glycosylphosphatidylin...
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Al-containing Ge-rich IWV: rapid synthesis via interzeolite transformation and application in Baeyer-Villiger oxidation
Ge-containing Lewis acidic zeolites are typically synthesized using a conventional hydrothermal strategy from amorphous silica sources, through a long time- and energy-consuming approach limiting their wide ap...
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Open AccessUSP47 deficiency in mice modulates tumor infiltrating immune cells and enhances antitumor immune responses in prostate cancer
This study investigates the role of USP47, a deubiquitinating enzyme, in the tumor microenvironment and its impact on antitumor immune responses. Analysis of TCGA database revealed distinct expression patterns...
