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  1. No Access

    Article

    The adipocytokine resistin stimulates the production of proinflammatory cytokines TNF-α and IL-6 in pancreatic acinar cells via NF-κB activation

    Background: Resistin, an adipocytokine secreted by fat tissues, has been associated with the inflammatory response, though its role in inflammation during acute pancreatitis (AP) remains unclear....

    C. Y. Jiang, W. Wang MD, J. X. Tang… in Journal of Endocrinological Investigation (2013)

  2. No Access

    Article

    Prevalence of cardiovascular risk factors in male and female patients with primary hyperparathyroidism

    Objective: To investigate the prevalence of cardiovascular risk factors in patients with primary hyperparathyroidism (PHPT) and to determine if they are gender specific. Methods: This was a retro...

    D. Han, S. Trooskin, X. Wang MD, PhD, FACE in Journal of Endocrinological Investigation (2012)

  3. No Access

    Article

    Potential treatment of hypoparathyroidism with recombinant plasmids encoding preproparathyroid hormone

    Hypoparathyroidism cannot be cured by oral or intravenous calcium supplements. Using molecular biology techniques to induce the production of PTH is an ideal option to treat hypoparathyroidism. In this study, ...

    D. Liu, Y. Zhu, C. Yang, J. Long, C. Yao… in Journal of Endocrinological Investigation (2012)

  4. No Access

    Article

    Association of angiotensin I converting enzyme, angiotensin II type 1 receptor and angiotensin I converting enzyme 2 gene polymorphisms with the dyslipidemia in Type 2 diabetic patients of Chinese Han origin

    Objective: To investigate whether the genetic polymorphisms in the angiotensin I converting enzyme (ACE) (insertion/deletion, or I/D), angiotensin II type 1 receptor (AT1R) (rs5186), and ACE2 (rs...

    Y. Xu, Q. Bao, B. He, Y. Pan, R. Zhang, X. Mao… in Journal of Endocrinological Investigation (2012)

  5. No Access

    Article

    The inhibitory effects of PKCθ on adiponectin expression is mediated by ERK in 3T3-L1 adipocytes

    The research suggests that adiponectin plays an important role in sensitizing insulin action. It is interesting to find that the lower levels of adiponectin exist in the plasma of obese and Type 2 diabetes sub...

    S. Sun, Y. Liu, J. Lu, A. Omar, S. Sun, Y. Bi… in Journal of Endocrinological Investigation (2011)

  6. No Access

    Article

    Correlation between adiponectin polymorphisms and non-alcoholic fatty liver disease with or without metabolic syndrome in Chinese population

    Background: To investigate the effect of single nucleotide polymorphisms (SNP) 45 and 276 of the adiponectin gene on non-alcoholic fatty liver disease (NAFLD) with or without metabolic sy...

    Z. L. Wang MD, PhD, B. **a, U. Shrestha… in Journal of Endocrinological Investigation (2008)

  7. No Access

    Article

    A five-year follow-up study of goiter and thyroid nodules in three regions with different iodine intakes in China

    Objective: The association between iodine status and the prevalence of goiter and thyroid nodules has been well established but the extent to which different iodine intake levels influenc...

    X. Yu, C. Fan, Z. Shan, X. Teng, H. Guan… in Journal of Endocrinological Investigation (2008)

  8. No Access

    Article

    Improved anti-apoptotic and anti-remodeling potency of bone marrow mesenchymal stem cells by anoxic pre-conditioning in diabetic cardiomyopathy

    Background: Bone marrow mesenchymal stem cells (MSC) mediate their protection by paracrine mechanism under ischemic conditions and anoxic pre-conditioning (AP) of MSC strongly enhances th...

    J. H. Li, N. Zhang, J. A. Wang MD, PhD in Journal of Endocrinological Investigation (2008)

  9. No Access

    Article

    B-type natriuretic peptide in patients with clinical hyperthyroidism

    Aims: To investigate the level and clinical significance of plasma B-type natriuretic peptide (BNP) in patients with hyperthyroidism. Methods: Plasma BNP was measured in 32 healthy subjects and 67 patients wit...

    T. Wei, C. Zeng, Y. Tian, Q. Chen… in Journal of Endocrinological Investigation (2005)

  10. No Access

    Article

    Hemoglobin A1c levels in non-diabetic patients with end-stage renal disease (ESRD) receiving hemodialysis

    Hemoglobin A1c (HbA1c) level represents an established tool to monitor glycemic control in diabetic patients, but the previous commonly used tests of HbA1c in patients with end-stage renal disease (ESRD) may not ...

    X. Wang MD, S. K. Peesapati, M. F. Renedo… in Journal of Endocrinological Investigation (2004)

  11. No Access

    Article

    Ongoing trials: What should we expect after ALLHAT?

    The publication of the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) results, when used in conjunction with a new meta-analysis, provides hypertension research with a wat...

    Ji-Guang Wang MD, Jan A. Staessen MD, PhD… in Current Hypertension Reports (2003)

  12. No Access

    Article

    The benefit of treating isolated systolic hypertension

    Isolated systolic hypertension affects over 15% of all people older than 60 years of age. In the elderly, systolic hypertension is a major modifiable cardiovascular risk factor. Systolic blood pressure is asso...

    Ji-Guang Wang MD, Jan A. Staessen MD, PhD in Current Hypertension Reports (2001)

  13. No Access

    Article

    Update: Role of the angiotensin type-2 (AT2) receptor in blood pressure regulation

    In the past, virtually all of the physiologic actions of angiotensin II (ANG II) were thought to be mediated by the type-1 ANG II receptor. However, there is now a compelling body of evidence suggesting that t...

    Robert M. Carey MD, Zhi-Qin Wang MD, Helmy M. Siragy MD in Current Hypertension Reports (2000)

  14. No Access

    Article

    Clinical trials in isolated systolic hypertension

    Isolated systolic hypertension affects 8% to 15% of all people older than 60 years of age. In the elderly, systolic hypertension is the major modifiable cardiovascular risk factor. Three placebo-controlled out...

    Jerzy Gasowski MD, Ji G. Wang MD, Jan A. Staessen MD, PhD in Current Hypertension Reports (1999)

  15. No Access

    Article

    Novel actions of angiotensin II via its renal type-2 (AT2) receptor

    The vast majority of the biologic effects of angiotensin II have been considered to be mediated by the subtype-1 (AT1) receptor. The AT2 receptor is expressed to a low degree in most adult cells and tissues, and ...

    Robert M. Carey MD, Zhi-Qin Wang MD, Helmy M. Siragy MD in Current Hypertension Reports (1999)