![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Ongoing trials: What should we expect after ALLHAT?
The publication of the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT) results, when used in conjunction with a new meta-analysis, provides hypertension research with a wat...
-
Article
The benefit of treating isolated systolic hypertension
Isolated systolic hypertension affects over 15% of all people older than 60 years of age. In the elderly, systolic hypertension is a major modifiable cardiovascular risk factor. Systolic blood pressure is asso...
-
Article
Update: Role of the angiotensin type-2 (AT2) receptor in blood pressure regulation
In the past, virtually all of the physiologic actions of angiotensin II (ANG II) were thought to be mediated by the type-1 ANG II receptor. However, there is now a compelling body of evidence suggesting that t...
-
Article
Clinical trials in isolated systolic hypertension
Isolated systolic hypertension affects 8% to 15% of all people older than 60 years of age. In the elderly, systolic hypertension is the major modifiable cardiovascular risk factor. Three placebo-controlled out...
-
Article
Novel actions of angiotensin II via its renal type-2 (AT2) receptor
The vast majority of the biologic effects of angiotensin II have been considered to be mediated by the subtype-1 (AT1) receptor. The AT2 receptor is expressed to a low degree in most adult cells and tissues, and ...