57 Result(s)

Article

Early cartilage lesion and 5-year incident joint surgery in knee osteoarthritis patients: a retrospective cohort study

to investigate the association between cartilage lesion-related features observed in knee osteoarthritis (OA) patients’ first MRI examination and incident knee surgery within 5 years. Additionally, to assess t...

Liu **ao-feng, Zhang **-shan, Zheng Yong-qiang… in BMC Musculoskeletal Disorders (2024)

Article

Effects of different types of Ringer’s solution on patients with traumatic haemorrhagic shock: a prospective cohort study

To compare the fluid resuscitation effect of sodium acetate Ringer’s solution and sodium bicarbonate Ringer’s solution on patients with traumatic haemorrhagic shock.

Qing Li, Qiang Yang, Chao Tian, Yao Guo, Hui Liu… in European Journal of Medical Research (2024)

Article

Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain

Extensive metastatic and refractory cancer pain is common, and exhibits a dissatisfactory response to the conventional intrathecal infusion of opioid analgesics.

Qing Li, Yan-ling Long, Yun-wu He, Hui Long, … in BMC Anesthesiology (2024)

Article

Age-related secretion of grancalcin by macrophages induces skeletal stem/progenitor cell senescence during fracture healing

Skeletal stem/progenitor cell (SSPC) senescence is a major cause of decreased bone regenerative potential with aging, but the causes of SSPC senescence remain unclear. In this study, we revealed that macrophag...

Nan-Yu Zou, Ran Liu, Mei Huang, Yu-Rui Jiao, Jie Wei, Yangzi Jiang… in Bone Research (2024)

Article

Physical therapy for end-stage hemophilic arthropathy: a case report

This report introduces a young adult who has been in bed for more than ten years with end-stage hemophilic arthropathy. He didn’t have access to factor VIII (FVIII) in the early stage of hemophilia due to the ...

Zhen-zhen Gao, Hang Yang, Wen-bin Liu, Cui Xu… in BMC Musculoskeletal Disorders (2023)

Article

Dynamic single-cell map** unveils Epstein‒Barr virus-imprinted T-cell exhaustion and on-treatment response

Epstein‒Barr virus (EBV)-associated gastric cancer (GC) manifests an intriguing immunotherapy response. However, the cellular basis for EBV-imprinted tumour immunity and on-treatment response remains undefined...

Miao-Zhen Qiu, Chaoye Wang, Zhiying Wu, Qi Zhao… in Signal Transduction and Targeted Therapy (2023)

Article

TERT mutations-associated alterations in clinical characteristics, immune environment and therapy response in glioblastomas

is the most frequently mutated gene in adult glioblastomas (GBMs) defined by the 2021 World Health Organization classification system. The present study aims to explore differences in clinical characteristics ...

Feng Tang, ** Chen, **-Sheng Liu, Zhen-Yuan Liu, **-Zhou Yang… in Discover Oncology (2023)

Article

Efficacy and safety of EGFR-TKIs in combination with angiogenesis inhibitors as first-line therapy for advanced EGFR-mutant non-small-cell lung cancer: a systematic review and meta-analysis

For patients with advanced non-small-cell lung cancer (NSCLC) with EGFR mutations, the suggested course of action is epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Even with a high di...

Di Hu, Yan-Yan Zhou, Hong-Bo Ma, Miao-Miao Tao, Qun-Zhen Huang… in BMC Pulmonary Medicine (2023)

Article

Nuclear AhR and membranous PD-L1 in predicting response of non-small cell lung cancer to PD-1 blockade

Si-Chong Han, Gui-Zhen Wang, Ya-Ning Yang… in Signal Transduction and Targeted Therapy (2023)

Article

Serine/threonine kinase TBK1 promotes cholangiocarcinoma progression via direct regulation of β-catenin

Cholangiocarcinoma (CCA) is a highly heterogeneous and metastatic malignancy with a poor prognosis even after curative hepatectomy. Studies exploring its pathogenesis and identifying effective therapeutic targ...

Chong-Qing Gao, Zhen-Zhen Chu, Di Zhang, Yang **ao, **ng-Yan Zhou, Jun-Ru Wu… in Oncogene (2023)

Article

Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2

Effective drugs with broad spectrum safety profile to all people are highly expected to combat COVID-19 caused by SARS-CoV-2. Here we report that nelfinavir, an FDA approved drug for the treatment of HIV infec...

Zhijian Xu, Danrong Shi, Jian-Bao Han, Yun Ling… in Signal Transduction and Targeted Therapy (2023)

Article

Stellate Ganglion Block Improves Postoperative Sleep Quality and Analgesia in Patients with Breast Cancer: A Randomized Controlled Trial

Postoperative impaired sleep quality and pain are associated with adverse outcomes. Stellate ganglion block (SGB) has shown promising results in enhancing sleep quality and alleviating neuropathic pain. This s...

Rui-zhi Yang, Yan-zhen Li, Min Liang, Jian-jun Yu, Ming-li Chen… in Pain and Therapy (2023)

Article

Excess mortality and associated factors among people living with HIV initiating highly active antiretroviral therapy in Luzhou, China 2006–2020

To estimate crude mortality, excess mortality, and standardized mortality rates (SMR) among people living with HIV (PLHIV) initiating highly active antiretroviral therapy (HAART) in Luzhou, China 2006–2020, an...

Dandan Niu, Ticheng **ao, Yuanyi Chen, Houlin Tang… in BMC Infectious Diseases (2023)

Article

Pleural effusion caused by Trichinella spiralis infection: two case reports

Trichinosis is a worldwide food-borne zoonotic parasitic disease, which is mainly obtained by ingesting undercooked meat containing infected larvae. The purpose of our article is to introduce and discuss two rare...

Zhen-zhen Pan, Miao-juan Zhu, Yu-qiong Rong, Jiong Yang in BMC Infectious Diseases (2023)

Article

Diffuse midline glioma treated with epigenetic agent-based immunotherapy

Linkai **g, Zhihong Qian, Qiang Gao, Rui Sun… in Signal Transduction and Targeted Therapy (2023)

Article

Correction to: Associations of combined healthy lifestyles with cancer morbidity and mortality among individuals with diabetes: results from five cohort studies in the USA, the UK and China

Yan-Bo Zhang, **ong-Fei Pan, Qi Lu, Yan-**u Wang, Ting-Ting Geng… in Diabetologia (2022)

Article

Correction to: Efficacy and Pharmacodynamic Target Attainment for Ceftazidime–Avibactam Off-Label Dose Regimens in Patients with Continuous or Intermittent Venovenous Hemodialysis: Two Case Reports

**ao-Shan Zhang, Yu-Zhen Wang, Da-Wei Shi, Fang-Min Xu… in Infectious Diseases and Therapy (2022)

Article

Associations of combined healthy lifestyles with cancer morbidity and mortality among individuals with diabetes: results from five cohort studies in the USA, the UK and China

Cancer has contributed to an increasing proportion of diabetes-related deaths, while lifestyle management is the cornerstone of both diabetes care and cancer prevention. We aimed to evaluate the associations o...

Yan-Bo Zhang, **ong-Fei Pan, Qi Lu, Yan-**u Wang, Ting-Ting Geng… in Diabetologia (2022)

Article

Efficacy and Pharmacodynamic Target Attainment for Ceftazidime–Avibactam Off-Label Dose Regimens in Patients with Continuous or Intermittent Venovenous Hemodialysis: Two Case Reports

Limited data are available for ceftazidime–avibactam (CZA) dosing in patients receiving renal replacement therapy, especially the data on the dosing in patients receiving intermittent hemodialysis (IHD). In th...

**ao-Shan Zhang, Yu-Zhen Wang, Da-Wei Shi, Fang-Min Xu… in Infectious Diseases and Therapy (2022)

Article

Size selection and placement of pedicle screws using robot-assisted versus fluoroscopy-guided techniques for thoracolumbar fractures: possible implications for the screw loosening rate

There has been increased development of robotic technologies for the accuracy of percutaneous pedicle screw placement. However, it remains unclear whether the robot really optimize the selection of screw sizes...

Sheng-yang Du, Jun Dai, Zhen-tao Zhou, Bing-chen Shan, Feng-xian Jiang… in BMC Surgery (2022)