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Article
Optimization of transverse electro-optic effect in LiNbO3 and LiTaO3 crystals
We analyze the transverse electro-optic (EO) effect in an arbitrary direction in LiNbO3 (LN) and LiTaO3 (LT) crystals based on the Fresnel index ellipsoid theory. A set of analytical formulas for calculating the ...
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Article
Enantioselective alkene hydroalkylation overcoming heteroatom constraints via cobalt catalysis
Alkene hydroalkylation enables efficient and selective formation of C(sp3)–C(sp3) bonds with unique advantages, such as exceptional chemoselectivity and remarkable tolerance of functional groups. However, elimina...
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Article
CRISPR-array-mediated imaging of non-repetitive and multiplex genomic loci in living cells
Dynamic imaging of genomic loci is key for understanding gene regulation, but methods for imaging genomes, in particular non-repetitive DNAs, are limited. We developed CRISPRdelight, a DNA-labeling system base...
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Article
Open AccessModel test study of bridge pile horizontal bearing behavior under landslide deformation
Pile is a common foundation on the slope, which poses a serious threat to the construction and operation if the slope deformation and causes landslide. In this study, a model device of pile foundation on lands...
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Article
Open AccessNicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis
Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying mechanism of nicotinate-curcumin (NC) in the treatment of NASH remain unce...
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Article
Pressure-driven metallization with significant changes of structural and photoelectric properties in two-dimensional EuSbTe3
Two-dimensional materials are widely considered to be highly promising for the development of photodetectors. To improve the performance of these devices, researchers often employ techniques such as defect eng...
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Article
Effectiveness of Lianhua Qingwen Granule and **gyin Gubiao Prescription in Omicron BA.2 Infection and Hospitalization: A Real-World Study of 56,244 Cases in Shanghai, China
To examine the effectiveness of Chinese medicine (CM) Lianhua Qingwen Granule (LHQW) and **gyin Gubiao Prescription (JYGB) in asymptomatic or mild patients with Omicron infection in the shelter hospital.
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Article
Open AccessNovel radiopaque ethanol injection: physicochemical properties, animal experiments, and clinical application in vascular malformations
Despite the efficacy of absolute ethanol (EtOH), its radiolucency introduces several risks in interventional therapy for treating vascular malformations. This study aims to develop a novel radiopaque ethanol i...
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Article
Open AccessAKI-Pro score for predicting progression to severe acute kidney injury or death in patients with early acute kidney injury after cardiac surgery
No reliable clinical tools exist to predict acute kidney injury (AKI) progression. We aim to explore a scoring system for predicting the composite outcome of progression to severe AKI or death within seven day...
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Article
Recognition and Classification of Concrete Surface Cracks with an Inception Quantum Convolutional Neural Network Algorithm
Current concrete surface crack detection methods cannot simultaneously achieve high detection accuracy and efficiency. Thus, this study focuses on the recognition and classification of crack images and propose...
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Article
Open AccessSerum selenium and fasting blood glucose: a cross-sectional study in women of different menopause status
This cross-sectional study aims to explore whether there exists an interaction between selenium and menopause concerning type 2 diabetes (T2D) prevalence and its related indicators such as fasting blood glucos...
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Article
Metabolomics efficiently discriminates monozygotic twins in peripheral blood
Monozygotic (MZ) twins cannot be distinguished using conventional forensic STR ty** because they present identical STR genoty**s. However, MZ twins do not always live in the same environment and often have...
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Article
Sex differences in hemoglobin levels and five-year refracture risk in patients with osteoporotic fractures: a retrospective cohort analysis
We conducted a retrospective cohort analysis to examine the association between hemoglobin (Hb) levels and refracture risk in elderly patients with osteoporotic fractures (OPFs). Our findings suggest a nonline...
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Article
Open AccessAssociation between pretreatment emotional distress and immune checkpoint inhibitor response in non-small-cell lung cancer
Emotional distress (ED), commonly characterized by symptoms of depression and/or anxiety, is prevalent in patients with cancer. Preclinical studies suggest that ED can impair antitumor immune responses, but fe...
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Article
Depression promotes breast cancer progression by regulating amino acid neurotransmitter metabolism and gut microbial disturbance
Breast cancer (BC) is the most prevalent type of cancer and has the highest mortality among women worldwide. BC patients have a high risk of depression, which has been recognized as an independent factor in th...
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Article
Open AccessMicrosecond-response perovskite light-emitting diodes for active-matrix displays
Perovskite light-emitting diodes (PeLEDs) could be of use in the development of active-matrix displays. However, due to ion migration in crystal structure, PeLEDs have electroluminescence rise times over milli...
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Article
Cotton fiber-based 1D nanocomposite: a new type of flexible wire for cryogenic electrical system
In response to the problem of poor flexibility of common one-dimensional flexible conductors at low temperatures, this paper proposed a one-dimensional flexible conductive composite material with cotton fiber ...
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Article
Constructing inter-diffusive PtCuNi/WO3 interface to enhance the catalytic activity and stability in oxygen reduction
Platinum-group-metal-based alloy nanocrystals have been considered as the most efficient catalysts for oxygen reduction reaction (ORR). However, the poor stability issues limit their further deployment in indu...
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Article
Macroscopic Dynamic Response and Microscopic Damage Formation Analysis of Steel Plates with Different Explosive Distances
As one of the protective components, the high strength low alloy structural steel plate had attracted extensive attention because of frequent threats of explosive loads. In this paper, combining explosion expe...
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Article
Microstructure Evolution and Nanomechanical Behavior of Micro-Area in Molten Pool of Selective Laser Melting (CoCrNi)82Al9Ti9 High-Entropy Alloy
In this work, the phase evolution mechanism and nanomechanical properties of (CoCrNi)82Al9Ti9 high-entropy alloy (HEA) prepared by selective laser melting (SLM) in the molten pool were studied. This HEA contains ...
