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Article
Evolution and function of residual solvent in polymer-Li2B12H12 composite solid electrolyte
Composite solid electrolytes (CSEs) containing polymer matrices and inorganic fillers hold promise for the next generation of solid-state batteries. However, the role of residual solvents in CSEs remains contr...
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Article
Recent advances in imaging devices: image sensors and neuromorphic vision sensors
Remarkable developments in image recognition technology trigger demands for more advanced imaging devices. In recent years, traditional image sensors, as the go-to imaging devices, have made substantial progre...
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Article
Targeted Therapy of Spinal Cord Injury: Inhibition of Apoptosis Is a Promising Therapeutic Strategy
Spinal cord injury (SCI) is a serious disabling central nervous system injury that can lead to motor, sensory, and autonomic dysfunction below the injury level. SCI can be divided into primary injury and secon...
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Article
Effects of heat treatment on microstructures and properties of a heterostructured alloy with dissimilar components fabricated by WAAM
Heat treatment significantly influences homogeneous material microstructures and mechanical properties, which can be improved by an optimal heat treatment process. However, heat treatment application to hetero...
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Article
Kv3.1 Interaction with UBR5 Is Required for Chronic Inflammatory Pain
Chronic inflammatory pain caused by neuronal hyperactivity is a common and refractory disease. Kv3.1, a member of the Kv3 family of voltage-dependent K+ channels, is a major determinant of the ability of neurons ...
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Article
Application of deep learning methods combined with physical background in wide field of view imaging atmospheric Cherenkov telescopes
The High Altitude Detection of Astronomical Radiation (HADAR) experiment, which was constructed in Tibet, China, combines the wide-angle advantages of traditional EAS array detectors with the high-sensitivity ...
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Article
Open AccessEndosymbionts of citrus leafminer Phyllocnistis citrella Stainton among different citrus orchards in China
Endosymbionts regulate the behavior of pest species, which could provide insights into their control. The citrus leafminer (Phyllocnistis citrella Stainton) is a widely distributed pest associated with diseases o...
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Article
Open AccessSignal enhancement ratio of multi-phase contrast-enhanced MRI: an imaging biomarker for survival in pancreatic adenocarcinoma
To evaluate signal enhancement ratio (SER) for tissue characterization and prognosis stratification in pancreatic adenocarcinoma (PDAC), with quantitative histopathological analysis (QHA) as the reference stan...
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Article
Open AccessRole of umbilical cord mesenchymal stromal cells in skin rejuvenation
Aging is the main cause of many degenerative diseases. The skin is the largest and the most intuitive organ that reflects the aging of the body. Under the interaction of endogenous and exogenous factors, there...
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Article
Well Logging Stratigraphic Correlation Algorithm Based on Semantic Segmentation
Well logging curves serve as indicators of strata attribute changes and are frequently utilized for stratigraphic analysis and comparison. Deep learning, known for its robust feature extraction capabilities, h...
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Article
Metagenomic analysis of individual mosquito viromes reveals the geographical patterns and drivers of viral diversity
Mosquito transmitted viruses are responsible for an increasing burden of human disease. Despite this, little is known about the diversity and ecology of viruses within individual mosquito hosts. Here, using a ...
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Article
Anti-corrosive and highly reversible zinc metal anode enabled by the phenolic resin coating
Aqueous zinc-ion batteries have attracted much attention due to their high theoretical capacity, low cost, high safety, and eco-friendly. However, challenges such as dendrite growth and side reactions severely...
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Article
DRP1 inhibition-mediated mitochondrial elongation abolishes cancer stemness, enhances glutaminolysis, and drives ferroptosis in oral squamous cell carcinoma
Mitochondrial dynamics play a fundamental role in determining stem cell fate. However, the underlying mechanisms of mitochondrial dynamics in the stemness acquisition of cancer cells are incompletely understood.
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Article
A novel mutation in hERG gene associated with azithromycin-induced acquired long QT syndrome
Mutations in human ether-à-go-go-related gene (hERG) potassium channels are closely associated with long QT syndrome (LQTS). Previous studies have demonstrated that macrolide antibiotics increase the risk of c...
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Article
Open AccessXELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial
Fluoropyrimidine-based combination chemotherapy plus targeted therapy is the standard initial treatment for unresectable metastatic colorectal cancer (mCRC), but the prognosis remains poor. This phase 3 trial ...
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Article
Recent advances in bioinspired vision systems with curved imaging structures
Limited by the planar imaging structure, the commercial camera needs to introduce additional optical elements to compensate for the curved focal plane to match the planar image sensor. This results in a comple...
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Article
Open AccessSugarcane borers: species, distribution, damage and management options
Lepidopteran borers stand out as the most destructive pests in sugarcane, leading to reductions in stalk weight, juice quality and sugar recovery. Presently, integrated pest management (IPM) systems are utiliz...
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Article
Open AccessReciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer
Squamous cell carcinomas (SCCs) are common and aggressive malignancies. Immune check point blockade (ICB) therapy using PD-1/PD-L1 antibodies has been approved in several types of advanced SCCs. However, low r...
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Article
Open AccessLactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model
Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...
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Article
Breeding of Saccharomyces cerevisiae with a High-Throughput Screening Strategy for Improvement of S-Adenosyl-L-Methionine Production
S-adenosyl-l-methionine (SAM), a vital physiologically active substance in living organisms, is produced by fermentation over Saccharomyces cerevisiae. The main limitation in SAM production was the low biosynthes...
