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  1. Article

    Open Access

    Effects of different types of Ringer’s solution on patients with traumatic haemorrhagic shock: a prospective cohort study

    To compare the fluid resuscitation effect of sodium acetate Ringer’s solution and sodium bicarbonate Ringer’s solution on patients with traumatic haemorrhagic shock.

    Qing Li, Qiang Yang, Chao Tian, Yao Guo, Hui Liu in European Journal of Medical Research (2024)

  2. No Access

    Article

    Gastrodin inhibits prostate cancer proliferation by targeting canonical Wnt/β-catenin signaling pathway

    Prostate cancer is an epithelial malignant tumor occurring in the prostate and is the most common malignant tumor in the male genitourinary system. In recent years, the incidence of prostate cancer in China ha...

    Ye-Mao Liu, An-Ding Wu, Yun Chen, Teng-Fei Ma, Bi-Zhen Dong in Medical Oncology (2023)

  3. Article

    Open Access

    miR-6076 rs1463411 polymorphisms are associated with bleeding during clopidogrel treatment in patients with acute coronary syndrome

    Bleeding is a major adverse event during clopidogrel treatment in patients with acute coronary syndrome (ACS). However, the potential mechanism affecting bleeding among individuals is unclear. Herein, we inves...

    Zhen-Zhen Mo, Zhen Yuan, Yuan-Yuan Peng in European Journal of Medical Research (2023)

  4. Article

    Open Access

    Decoding the underlying mechanisms of Di-Tan-Decoction in treating intracerebral hemorrhage based on network pharmacology

    Chinese medicine usually acts as "multi-ingredients, multi-targets and multi-pathways" on complex diseases, and these action modes reflect the coordination and integrity of the treatment process with tradition...

    Zheng Zhen, Dao-** Xue, Yu-peng Chen in BMC Complementary Medicine and Therapies (2023)

  5. No Access

    Article

    A prognostic survival nomogram for persons with extra-nodal natural killer-/T-cell lymphoma

    Hua Wang, Bi-bo Fu, Zhi-jun Wuxiao, Ya-jun Li, Li Huang, Jie Ma, Zhi-min Zhai in Leukemia (2022)

  6. Article

    Open Access

    The efficacy and safety of ciprofol use for the induction of general anesthesia in patients undergoing gynecological surgery: a prospective randomized controlled study

    Ciprofol is a recently developed, short-acting γ-aminobutyric acid receptor agonist sedative that is more potent than propofol, but there have been few clinical studies of this agent to date. Here, we sought t...

    Ben-zhen Chen, **n-yu Yin, Li-hua Jiang, **-hui Liu, Yan-yan Shi in BMC Anesthesiology (2022)

  7. Article

    Open Access

    Uncovering the potential mechanism of Xue Fu Zhu Yu Decoction in the treatment of intracerebral hemorrhage

    Chinese herbal medicine (CHM) is characterized by “multi- compounds, multi-targets and multi-pathway”, which has advanced benefits for preventing and treating complex diseases, but there still exists unsolved ...

    Dao-** Xue, Zheng Zhen, Ke-xin Wang in BMC Complementary Medicine and Therapies (2022)

  8. No Access

    Article

    Hepatic Vps33b deficiency aggravates cholic acid-induced cholestatic liver injury in male mice

    Vacuolar protein sorting 33B (VPS33B) is important for intracellular vesicular trafficking process and protein interactions, which is closely associated with the arthrogryposis, renal dysfunction, and cholesta...

    Kai-li Fu, Pan Chen, Yan-ying Zhou, Yi-ming Jiang, Yue Gao in Acta Pharmacologica Sinica (2022)

  9. No Access

    Article

    FSHR ablation induces depression-like behaviors

    Alteration in reproductive hormones profile is associated with the increasing risk of menopausal depression in women. Serum follicle-stimulating hormone (FSH) level is changed during the menopause transition, ...

    Wen-kai Bi, Shan-shan Shao, Zhi-wei Li, Yong-wei Ruan in Acta Pharmacologica Sinica (2020)

  10. No Access

    Article

    Bilateral pelvic lymph node dissection for Chinese patients with penile cancer: a multicenter collaboration study

    Current guidelines recommend pelvic lymphadenectomy (PLND) for patients with pelvic lymph node metastasis and special state. However, these data and recommendations do not distinguish the role of PLND in diffe...

    Zai-Shang Li, Chuang-Zhong Deng, Kai Yao in Journal of Cancer Research and Clinical On… (2017)

  11. No Access

    Article

    Wharton’s Jelly-derived mesenchymal stem cells alleviate memory deficits and reduce amyloid-β deposition in an APP/PS1 transgenic mouse model

    Alzheimer’s disease (AD) is the leading cause of dementia in the elderly and is characterized by amyloid plaques, neurofibrillary tangles, and neuronal loss. Cumulative evidence supports that neuroinflammation...

    Zhao-Hong **e, Zhen Liu, **ao-Ran Zhang, Hui Yang in Clinical and Experimental Medicine (2016)