46 Result(s)
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High-Resolution Melting (HRM) analysis of DNA methylation using semiconductor chip-based digital PCR
Digital PCR (dPCR) technology allows absolute quantification and detection of disease-associated rare variants, and thus the use of dPCR technology has been increasing in clinical research and diagnostics. The...
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Exploring oral bacterial compositional network in two oral disease groups using a convergent approach of NGS-molecular diagnostics
Since most of the commonly known oral diseases are explained in link with balance of microbial community, an accurate bacterial taxonomy profiling for determining bacterial compositional network is essential. ...
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Open AccessFermentative aminopyrrolnitrin production by metabolically engineered Corynebacterium glutamicum
Aminopyrrolnitrin (APRN), a natural halogenated phenylpyrrole derivative (HPD), has strong antifungal and antiparasitic activities. Additionally, it showed 2.8-fold increased photostability compared to pyrroln...
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Development of fluorescence-linked immunosorbent assay for rapid detection of Staphylococcus aureus
Staphylococcus aureus is a major pathogen that causes infections and life-threatening diseases. Although antibiotics, such as methicillin, have been used, methicillin-resistant S. aureus (MRSA) causes high morbid...
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Open AccessLoop-mediated isothermal amplification assay for screening congenital cytomegalovirus infection in newborns
Congenital cytomegalovirus (CMV) infection is a common cause of sensorineural hearing loss and neurodevelopmental impairment in newborns. However, congenital CMV infection cannot be diagnosed using samples col...
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Open AccessAlterations in sea urchin (Mesocentrotus nudus) microbiota and their potential contributions to host according to barren severity
Sea urchins are biotic factors driving the decline of kelp forests in marine ecosystems. However, few studies have analyzed the microbiota of surviving sea urchins in barren regions with scarce diet resources....
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Open AccessMulti-omics data of gastric cancer cell lines
Gastric cancer (GC) is the fourth most common cancer worldwide, with the highest incidence and mortality regardless of sex. Despite technological advances in diagnosing and treating gastric cancer, GC still ha...
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Open AccessIdentification and phylogenetic analysis of Enterococcus isolates using MALDI-TOF MS and VITEK 2
The bacterial genus Enterococcus encompasses 38 species. Two of the most common species are E. faecalis and E. faecium. Recently, however, there has been an increase in clinical reports concerning less prevalent
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Open AccessIsopropanol biosynthesis from crude glycerol using fatty acid precursors via engineered oleaginous yeast Yarrowia lipolytica
Isopropanol is widely used as a biofuel and a disinfectant. Chemical preparation of isopropanol destroys the environment, which makes biological preparation of isopropanol necessary. Previous studies focused o...
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Open AccessGenomic and transcriptomic analysis of Korean colorectal cancer patients
Colorectal cancer (CRC) is the third most common type of diagnosed cancer in the world and has the second-highest mortality rate. Meanwhile, South Korea has the second-highest incidence rate for CRC in the world.
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Open AccessIdentification of accession-specific variants and development of KASP markers for assessing the genetic makeup of Brassica rapa seeds
Most crop seeds are F1 hybrids. Seed providers and plant breeders must be confident that the seed supplied to growers is of known, and uniform, genetic makeup. This requires maintenance of pure genotypes of th...
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Open AccessHost tp53 mutation induces gut dysbiosis eliciting inflammation through disturbed sialic acid metabolism
Host tp53 mutations are frequently found during the early stages of colitis-associated colorectal cancer (CAC), but whether such mutations induce gut microbiota dysbiosis and chronic intestinal inflammation that ...
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Comparison between MGI and Illumina sequencing platforms for whole genome sequencing
Illumina next generation sequencing (NGS) systems are the major sequencing platform in worldwide next-generation sequencing market. On the other hand, MGI Tech launched a series of new NGS equipment that promi...
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Open AccessQTL map** for pre-harvest sprouting resistance in japonica rice varieties utilizing genome re-sequencing
Pre-harvest sprouting (PHS) leads to serious economic losses because of reductions in yield and quality. To analyze the quantitative trait loci (QTLs) for PHS resistance in japonica rice, PHS rates on panicles we...
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Open AccessAbsence of single nucleotide polymorphisms (SNPs) in the open reading frame (ORF) of the prion protein gene (PRNP) in a large sampling of various chicken breeds
Prion diseases are zoonotic diseases with a broad infection spectrum among mammalian hosts and are caused by the misfolded prion protein (PrPSc) derived from the normal prion protein (PrPC), which encodes the pri...
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Open AccessPharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers
Gynecologic malignancy is one of the leading causes of mortality in female adults worldwide. Comprehensive genomic analysis has revealed a list of molecular aberrations that are essential to tumorigenesis, pro...
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Seroprevalence of Severe Fever with Thrombocytopenia Syndrome Phlebovirus in Domesticated Deer in South Korea
Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) has a wide host range. Not only has it been found in humans, but also in many wild and domesticated animals. The infection of breeding deer on fa...
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Open AccessRaptor genomes reveal evolutionary signatures of predatory and nocturnal lifestyles
Birds of prey (raptors) are dominant apex predators in terrestrial communities, with hawks (Accipitriformes) and falcons (Falconiformes) hunting by day and owls (Strigiformes) hunting by night.
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Open AccessPerformance evaluation of commercial library construction kits for PCR-based targeted sequencing using a unique molecular identifier
Target enrichment is a critical component of targeted deep next-generation sequencing for the cost-effective and sensitive detection of mutations, which is predominantly performed by either hybrid selection or...
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Open AccessCorrection to: Genomic and metatranscriptomic analyses of carbon remineralization in an Antarctic polynya
Following publication of the original article [1], the authors identified wrong citations in the maintext.
