1,865 Result(s)
within
**-Tao Gao
-
Article
Open AccessMultivariate associations between neuroanatomy and cognition in unmedicated and medicated individuals with schizophrenia
Previous studies that focused on univariate correlations between neuroanatomy and cognition in schizophrenia identified some inconsistent findings. Moreover, antipsychotic medication may impact the brain-behav...
-
Article
Open AccessEvaluation of vaccine candidates against Rhodococcus equi in BALB/c mice infection model: cellular and humoral immune responses
Rhodococcus equi (R. equi) is a zoonotic opportunistic pathogen that mainly causes fatal lung and extrapulmonary abscesses in foals and immunocompromised individuals. To date, no commercial vaccine against R. equ...
-
Article
Development and first-in-human study of PSMA-targeted PET tracers with improved pharmacokinetic properties
A series of new 68Ga-labeled tracers based on [68Ga]Ga-PSMA-617 were developed to augment the tumor-to-kidney ratio and reduce the activity accumulation in bladder, ultimately minimize radiation toxicity to the u...
-
Article
Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor
Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins, showing a potential threat to humans. Here we report the infectivity and pathogenicity of the SARS-CoV-2-related virus, ...
-
Article
Enzyme-activatable disk-shaped nanocarriers augment tumor permeability for breast cancer combination therapy
Unique physiopathological characteristics of tumor tissues impose obstacles to the sufficient penetration of traditional nanomedicines, resulting in undesirable drug delivery efficacy and therapeutic outcomes....
-
Article
Remote assessment of Parkinson’s disease symptom severity based on group interaction feature assistance
Telemonitoring is an effective way to assess the severity of Parkinson's disease (PD). Due to heterogeneity and small sample sizes, the multi-task learning is applied to build the specific model for PD patient...
-
Article
REDQT: a method for automated mobile application GUI testing based on deep reinforcement learning algorithms
As mobile applications become increasingly prevalent in daily life, the demand for their functionality and reliability continues to grow. Traditional mobile application testing methods, particularly graphical ...
-
Article
Open AccessRadiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma by inducing active transformation of tumor-infiltrating CD8+ T and NK cells
Immunosuppression by the tumor microenvironment is a pivotal factor contributing to tumor progression and immunotherapy resistance. Priming the tumor immune microenvironment (TIME) has emerged as a promising s...
-
Article
Open AccessNotoginsenoside R1 promotes Lgr5+ stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling
Inflammatory bowel disease (IBD) is characterized by persistent damage to the intestinal barrier and excessive inflammation, leading to increased intestinal permeability. Current treatments of IBD primarily ad...
-
Article
Open AccessCACA guidelines for holistic integrative management of anticancer treatment - induced cutaneous adverse events
The skin and mucous membrane of cancer patients can be directly or indirectly impaired during the treatment of cancers, bringing about not physical but also psychological damages to cancer patients. A practica...
-
Article
Open AccessSearch for central exclusive production of top quark pairs in proton-proton collisions at \( \sqrt{s} \) = 13 TeV with tagged protons
A search for the central exclusive production of top quark-antiquark pairs ( t t ...
-
Article
Open AccessMeasurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...
-
Article
Open AccessSearch for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at ...
-
Article
Unleashing the Power of Bio-based Thermotropic Liquid Crystal Modifiers: Toughening and Reinforcing Petroleum-based Epoxy Resin without Compromising Other Properties
Toughening the petroleum-based epoxy resin blends with bio-based modifiers without compromising their modulus, mechanical strength, and other properties is still a big challenge in view of the sustainability. ...
-
Article
Open AccessIntestinal mRNA expression profiles associated with mucosal healing in ustekinumab-treated Crohn's disease patients: bioinformatics analysis and prospective cohort validation
Variations exist in the response of patients with Crohn’s disease (CD) to ustekinumab (UST) treatment, but the underlying cause remains unknown. Our objective was to investigate the involvement of immune cells...
-
Article
Open AccesscGAS-ISG15-RAGE axis reprogram necroptotic microenvironment and promote lymphatic metastasis in head and neck cancer
Cancer cells frequently evolve necroptotic resistance to overcome various survival stress during tumorigenesis. However, we have previously showed that necroptosis is widespread in head and neck squamous cell ...
-
Article
Open AccessDrug-coated balloon angioplasty with provisional stenting versus primary stenting for the treatment of de novo coronary artery lesions: REC-CAGEFREE I trial rationale and design
Percutaneous coronary intervention (PCI) with primary stenting, which stands for stent implantation regardless of obtaining satisfactory results with balloon angioplasty, has superseded conventional plain old ...
-
Article
Genotypic richness affects inorganic N uptake and N form preference of a clonal plant via altering soil N pools
Similar to species richness, genotypic richness of plants plays a pivotal role in the structure and function of ecosystems. While the contribution of intraspecific variability to ecosystem function has been we...
-
Article
Open AccessCorrelation of bilateral M1 hand area excitability and overall functional recovery after spinal cord injury: protocol for a prospective cohort study
After spinal cord injury (SCI), a large number of survivors suffer from severe motor dysfunction (MD). Although the injury site is in the spinal cord, excitability significantly decreases in the primary motor ...
-
Article
Open AccessHuman parasitic infections of the class Adenophorea: global epidemiology, pathogenesis, prevention and control
Human parasitic infections caused by Adenophorean nematodes encompass a range of diseases, including dioctophymiasis, trichuriasis, capillariasis, trichinellosis, and myositis. These infection can result in ad...
