954 Result(s)
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Open AccessNatural variation of TBR confers plant zinc toxicity tolerance through root cell wall pectin methylesterification
Zinc (Zn) is an essential micronutrient but can be cytotoxic when present in excess. Plants have evolved mechanisms to tolerate Zn toxicity. To identify genetic loci responsible for natural variation of plant ...
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Open AccessCombined detection of serum EFNA1 and MMP13 as diagnostic biomarker for gastric cancer
We previously identified that serum EFNA1 and MMP13 were potential biomarker for early detection of esophageal squamous cell carcinoma. In this study, our aim is to explore the diagnostic value of serum EFNA1 ...
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Open AccessErythroid-intrinsic activation of TLR8 impairs erythropoiesis in inherited anemia
Inherited non-hemolytic anemia is a group of rare bone marrow disorders characterized by erythroid defects. Although concerted efforts have been made to explore the underlying pathogenetic mechanisms of these ...
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Open AccessThe effects of temperament type on infusion extravasation in newborns
Infusion extravasation has an increased incidence in newborns, which can result in various adverse outcomes. This study aimed to investigate the effects of different types of temperament on infusion extravasat...
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Open AccessActivation of PPAR-α attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis and mitochondrial injury via upregulating 14-3-3η
This study aimed to explore the effects of peroxisome proliferator-activated receptor α (PPAR-α), a known inhibitor of ferroptosis, in Myocardial ischemia/reperfusion injury (MIRI) and its related mechanisms. ...
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Open AccessA multimodal physiological and psychological dataset for human with mental stress induced myocardial ischemia
Accurate differentiation between angina with no obstructive coronary arteries (ANOCA) and mental stress-induced myocardial ischemia (MSIMI) is crucial for tailored treatment strategies, yet public data scarcit...
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Open AccessAnalysis of physical and mechanical behaviors and microscopic mineral characteristics of thermally damaged granite
Temperature’s influence on the physical and mechanical properties of rocks is a crucial concern for the rational design of deep rock engineering structures and the assurance of their long-term stability. To sy...
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Open AccessSuccinate promotes pulmonary fibrosis through GPR91 and predicts death in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is believed to be associated with a notable disruption of cellular energy metabolism. By detecting the changes of energy metabolites in the serum of patients with pulmonary ...
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Open AccessA complete reference genome of broomcorn millet
Broomcorn millet (Panicum miliaceum L.), known for its traits of drought resistance, adaptability to poor soil, short growth period, and high photosynthetic efficiency as a C4 plant, represents one of the earlies...
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Open AccessHearing loss and its association with the proteome of perilymph, cerebrospinal fluid, and tumor tissue in patients with vestibular schwannoma
This study examined the association between hearing loss in sporadic vestibular schwannoma patients and the proteome of perilymph (PL), cerebrospinal fluid (CSF), and vestibular schwannoma. Intraoperative samp...
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Open AccessCholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma
Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell lymphoma (DLBCL). However, its efficacy in treating primary ref...
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Open AccessInhibiting perovskite decomposition by a creeper-inspired strategy enables efficient and stable perovskite solar cells
The commercialization of perovskite solar cells is badly limited by stability, an issue determined mainly by perovskite. Herein, inspired by a natural creeper that can cover the walls through suckers, we adopt...
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Open AccessThe comparison of white-to-white via triple person-times caliper measuring and machine-measuring in V4c implantable collamer lens implantation
This study aimed to compare the differences and characteristics of white-to-white (WTW) values obtained before V4c implantation using triple person-times caliper, IOL-Master 700, Pentacam HR, and UBM, and to a...
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Open AccessMitochondria from osteolineage cells regulate myeloid cell-mediated bone resorption
Interactions between osteolineage cells and myeloid cells play important roles in maintaining skeletal homeostasis. Herein, we find that osteolineage cells transfer mitochondria to myeloid cells. Impairment of...
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Open AccessSolar overall water-splitting by a spin-hybrid all-organic semiconductor
Direct solar-to-hydrogen conversion from pure water using all-organic heterogeneous catalysts remains elusive. The challenges are twofold: (i) full-band low-frequent photons in the solar spectrum cannot be har...
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Open AccessA bioinspired surface tension-driven route toward programmed cellular ceramics
The intriguing biomineralization process in nature endows the mineralized biological materials with intricate microarchitected structures in a facile and orderly way, which provides an inspiration for processi...
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Open AccessCuproptosis-related lncRNA signature as a prognostic tool and therapeutic target in diffuse large B cell lymphoma
Cuproptosis is a newly defined form of programmed cell death that relies on mitochondria respiration. Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis and metastasis. However, whether cupropto...
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Open AccessA biodegradable and flexible neural interface for transdermal optoelectronic modulation and regeneration of peripheral nerves
Optoelectronic neural interfaces can leverage the photovoltaic effect to convert light into electrical current, inducing charge redistribution and enabling nerve stimulation. This method offers a non-genetic a...
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Open AccessAnti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8+T cells for systemic antitumor responses
Immune checkpoint blockade (ICB) therapies function by alleviating immunosuppression on tumor-infiltrating lymphocytes (TILs) but are often insufficient to fully reactivate these dysfunctional TILs. Although i...
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Open AccessMulti-resource dynamic coordinated planning of flexible distribution network
The flexible distribution network presents a promising architecture to accommodate highly integrated distributed generators and increasing loads in an efficient and cost-effective way. The distribution network...
