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Open AccessSimultaneous integrated boost intensity-modulated radiotherapy post breast-conserving surgery: clinical efficacy, adverse effects, and cosmetic outcomes in breast cancer patients
Simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) is an innovative technique delivering a higher dose to the tumor bed while irradiating the entire breast. This study aims to assess the...
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Article
Simultaneously Improved Curing, Mechanical, Antioxidative Properties and Reduced ZnO Loading of Silica Filled NR Composites by Incorporation of Low-cost Crude Carbon Dots via Conventional Melt-milling Method
Rubbers or elastomers play an important role in hi-tech technology and civilian daily life because of their unique and strategical properties. Generally, the rubber additives are essential components for rubbe...
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Article
Culture of cerebrospinal fluid-contacting neurons from neonatal mouse spinal cord
Cerebrospinal fluid-contacting neurons (CSF-cNs) act crucial role in chemosensory and mechanosensory function in spinal cord. Recently, CSF-cNs were found to be an immature neuron and may be involved in spinal...
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Article
Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway
The angiotensin II type 2 receptor (AT2R) is a well-established component of the renin-angiotensin system and is known to counteract classical activation of this system and protect against organ damage. Pharma...
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Liquid–metal microgrid stretchable electronics based on bionic leaf veins with ultra-stretchability and high conductivity
Stretchable electronics that monitor joint activity and treat diseases based on liquid metal could be used in the development of healthcare applications. Such devices can be seamlessly integrated with human sk...
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Article
Open AccessSpatiotemporal multi-omics: exploring molecular landscapes in aging and regenerative medicine
Aging and regeneration represent complex biological phenomena that have long captivated the scientific community. To fully comprehend these processes, it is essential to investigate molecular dynamics through ...
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Article
O2 adsorption on Fe3O4 (110) surface and effect of gangue element Al do**: combined study of binding experiment and ab initio molecular dynamics
At high temperature, the chemical reaction mechanism at the interface of magnetite and the influence mechanism of gangue element Al on the oxidation performance of magnetite are not clear. In addition, due to ...
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Article
Open AccessImpact of Immunosuppressed Status on Prognosis of Carbapenem-Resistant Organisms Bloodstream Infections
The impact of immunosuppression on prognosis of carbapenem-resistant organism (CRO) bloodstream infection (BSI) remains unclear. The aim of this study was to clarify the relationship between immunosuppression ...
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Article
Open AccessGenetic drivers of heterogeneity in type 2 diabetes pathophysiology
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic c...
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Article
Charge regulation by ferromagnetic metal/LiF spin-polarized interface for high-performance Li metal anodes
The interfacial characteristics of the Li metal anode (LMA) play a crucial role in its overall performance. Despite various materials being applied to modify the interface, a comprehensive understanding of the...
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Article
Open AccessThe causal effects of genetically predicted alcohol consumption on endometrial cancer risk from a Mendelian randomization study
Endometrial cancer (EC) is a common gynecological tumor in females with an increasing incidence over the past few decades. Alcohol consumption has been linked to the occurrence of various cancers; However, epi...
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Article
The energy response of LaBr \(_{3}\) (Ce), LaBr \(_{3}\) (Ce,Sr), and NaI(Tl) crystals for GECAM
The GECAM series of satellites utilizes LaBr \(_3\) 3 ...
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Article
Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n
Nondestructive and noninvasive neutron assays are essential applications of neutron techniques. Neutron resonance transmission analysis (NRTA) is a powerful nondestructive method for investigating the elementa...
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Open AccessNovel nanotherapeutics for cancer immunotherapy by albumin nanoparticles functionalized with PD-1 and PD-L1 aptamers
PD-1/PD-L1 blockade plays a crucial role in cancer immunotherapy. Exploration of new technologies to further enhance the efficacy of PD-1/PD-L1 blockade is therefore of potential medical importance. Nanotherap...
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Article
Subgrade settlements of existing railway lines and operational parameters of shield machine induced by twin shield tunnel excavations: A case study
This paper presents a case study on the subgrade settlements of four national railway lines induced by twin shield tunnel excavations. The development characteristics of subgrade settlements can be divided int...
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Author Correction: Discovery of toxoflavin, a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition
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Open AccessSearch for Z′ bosons decaying to pairs of heavy Majorana neutrinos in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for the production of pairs of heavy Majorana neutrinos (Nℓ) from the decays of Z′ bosons is performed using the CMS detector at the LHC. The data were collected in proton-proton collisions at a center-o...
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Article
ATF4 renders human T-cell acute lymphoblastic leukemia cell resistance to FGFR1 inhibitors through amino acid metabolic reprogramming
Abnormalities of FGFR1 have been reported in multiple malignancies, suggesting FGFR1 as a potential target for precision treatment, but drug resistance remains a formidable obstacle. In this study, we explored...
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Article
Open AccessQuantum storage of entangled photons at telecom wavelengths in a crystal
Quantum storage and distribution of entanglement are the key ingredients for realizing a global quantum internet. Compatible with existing fiber networks, telecom-wavelength entangled photons and corresponding...
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Article
Open AccessMeasurement of the top quark mass using a profile likelihood approach with the lepton + jets final states in proton–proton collisions at \(\sqrt{s}=13\,\text {Te}\hspace{-.08em}\text {V} \)
The mass of the top quark is measured in 36.3 \(\,\text {fb}^{-1}\) ...
