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    Article

    A synergistic partnership between IL-33/ST2 and Wnt pathway through Bcl-xL drives gastric cancer stemness and metastasis

    ST2 functions as a receptor for the cytokine IL-33. It has been implicated in carcinogenesis. In this study, we sought to mechanistically determine how ST2 and IL-33 function to support cancer stem cell (CSC) ...

    Jong-Wan Kwon, Sang-Hyuk Seok, Somi Kim, Hyeok-Won An, Anahita Dev Choudhury in Oncogene (2023)

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    Article

    Recapitulation of pharmacogenomic data reveals that invalidation of SULF2 enhance sorafenib susceptibility in liver cancer

    Gene mutations play critical roles during cancer development and progression, and therefore represent targets for precision medicine. Here we recapitulated the pharmacogenomic data to delineate novel candidate...

    Sarah Yoon, Eun-Ju Lee, Ji-Hye Choi, Taek Chung, Do Young Kim, Jong-Yeop Im in Oncogene (2018)