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  1. No Access

    Article

    Mutational analysis of pig tissue factor pathway inhibitor α to increase anti-coagulation activity in pig-to-human xenotransplantation

    Blood coagulation mediated by pig tissue factor (TF), which is expressed in pig tissues, causes an instant blood-mediated inflammatory reaction during pig-to-human xenotransplantation. Previously, we generated...

    Chang-Hee Lee, Hyeon Jeong Lee, Si-Won Park, Jiyoon Shin in Biotechnology Letters (2024)

  2. No Access

    Article

    Assessment of the predictive capabilities of various turbulence models for the simulation of rotating stall in the centrifugal pump impeller

    The rotating stall generated by the centrifugal pump impeller reduces efficiency and causes severe flow fluctuations and noise due to surging. In the present work, the six-bladed impeller in the centrifugal pu...

    Sang Hwan Park, Gong Hee Lee, Dong Kim, Kyoungsik Chang in Journal of Visualization (2024)

  3. Article

    Open Access

    Advanced parametrization for the production of high-energy solid-state lithium pouch cells containing polymer electrolytes

    Lithium batteries with solid-state electrolytes are an appealing alternative to state-of-the-art non-aqueous lithium-ion batteries with liquid electrolytes because of safety and energy aspects. However, engine...

    Wonmi Lee, Juho Lee, Taegyun Yu, Hyeong-Jong Kim, Min Kyung Kim in Nature Communications (2024)

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    Article

    Comparative analysis of reduced toxicity conditioning regimens between fludarabine plus melphalan and fludarabine plus busulfex in adult patients with acute lymphoblastic leukemia

    Reduced-toxicity conditioning (RTC) regimens aim to mitigate regimen-related toxicity while maintaining anti-leukemic efficacy in allogeneic hematopoietic stem cell transplantation (allo-HSCT). We assessed out...

    Jaehyun Ahn, Jae-Ho Yoon, Daehun Kwag, Gi June Min in Bone Marrow Transplantation (2024)

  5. Article

    Open Access

    GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory

    Impaired ion channels regulating Golgi pH lead to structural alterations in the Golgi apparatus, such as fragmentation, which is found, along with cognitive impairment, in Alzheimer’s disease. However, the cau...

    Hyunji Kang, Ah-reum Han, Aihua Zhang, Hee** Jeong, Wuhyun Koh in Nature Communications (2024)

  6. Article

    Open Access

    Use of cortical hemodynamic responses in digital therapeutics for upper limb rehabilitation in patients with stroke

    Stroke causes long-term disabilities, highlighting the need for innovative rehabilitation strategies for reducing residual impairments. This study explored the potential of functional near-infrared spectroscop...

    **uk Kim, Eunmi Kim, Su-Hyun Lee in Journal of NeuroEngineering and Rehabilita… (2024)

  7. No Access

    Article

    Lower incidence of acute graft-versus-host disease with post-transplantation cyclophosphamide compared to anti-thymocyte globulin in higher-risk myelodysplastic syndrome

    Eun-Ji Choi, **-Hee Han, Hyunkyung Park, Han-Seung Park in Bone Marrow Transplantation (2024)

  8. No Access

    Article

    Electrochemical Immunoassay Using Diffusion Layer Dispersion Effect of Electrodes

    Diffusion layer dispersed electrodes were presented for application in electrochemical immunoassays. The diffusion layer refers to the region on the electrode surface where concentration gradients occur during...

    Eunyoung Kim, Jun-Hee Park, Bong-Ki Ryu, Ga-Yeon Lee in BioChip Journal (2024)

  9. Article

    Open Access

    Vertiport navigation requirements and multisensor architecture considerations for urban air mobility

    Communication, Navigation and Surveillance (CNS) technologies are key enablers for future safe operation of drones in urban environments. However, the design of navigation technologies for these new applicatio...

    Omar García Crespillo, Chen Zhu, Maximilian Simonetti in CEAS Aeronautical Journal (2024)

  10. No Access

    Article

    Effect of air-frying on formation and correlations of polycyclic aromatic hydrocarbons, acrylamide, and heterocyclic aromatic amines in foods and risk assessment

    The levels of acrylamide (AA), four polycyclic aromatic hydrocarbons (PAH4), and heterocyclic aromatic amines (HAAs) in 184 air-fried agricultural, fishery, and animal products were measured using GC–MS and UP...

    Hyeri Yoon, Mun Yhung Jung, Sung-Hee Choi, Su-Hyun Chun in Food Science and Biotechnology (2024)

  11. Article

    Open Access

    Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse

    Alzheimer's disease (AD) is a common type of dementia characterized by amyloid-β (Aβ) accumulation, lysosomal dysfunction, and tau hyperphosphorylation, leading to neurite dystrophy and memory loss. This study...

    Seungmin Lee, In Gyoung Ju, Hyeyoon Eo, ** Hee Kim, Yu** Choi in Chinese Medicine (2024)

  12. No Access

    Article

    Comparison of laser and traditional lancing devices for capillary blood sampling in patients with diabetes mellitus and high bleeding risk

    Despite the importance of self-monitoring blood glucose (SMBG) for management of diabetes mellitus (DM), frequent blood sampling is discouraged by bleeding risk due to dual-antiplatelet agent therapy (DAPT) or...

    Min Jeong Park, Soon Young Hwang, Ahreum Jang, Soo Yeon Jang in Lasers in Medical Science (2024)

  13. Article

    Open Access

    Comparative analysis of F-18 FDG PET/CT images between scrub typhus and systemic lupus erythematosus

    This study evaluated the use of F-18 fluorodeoxyglucose (FDG) PET/CT imaging to differentiate between scrub typhus and systemic lupus erythematosus (SLE) in patients presenting with lymphadenopathy. We carried...

    Yeon-Hee Han, Joo-Hee Hwang, Yunjung Choi, Chang-Seop Lee in Scientific Reports (2024)

  14. No Access

    Article

    Advancing biofoundry development: strategies and challenges

    This study explores the development of biofoundries, emphasizing the integration of synthetic biology with artificial intelligence (AI) and robotics. It outlines critical challenges such as the necessity for i...

    Aporva Gupta, Seung-Goo Lee, Bong-Hyun Sung in Biotechnology and Bioprocess Engineering (2024)

  15. Article

    Open Access

    Catabolism of 2-keto-3-deoxy-galactonate and the production of its enantiomers

    2-Keto-3-deoxy-galactonate (KDGal) serves as a pivotal metabolic intermediate within both the fungal d-galacturonate pathway, which is integral to pectin catabolism, and the bacterial DeLey-Doudoroff pathway for

    Eun Ju Yun, Sun-Hee Lee, Subin Kim, Hae Seul Ryu in Applied Microbiology and Biotechnology (2024)

  16. No Access

    Article

    Prognostic Impact of Inflammation-Based Factors in Patients with Esophageal Squamous Cell Carcinoma Achieving Pathological Complete Response After Neoadjuvant Chemoradiotherapy Followed by Surgery

    Patients achieving pathological complete response (pCR) post-neoadjuvant chemoradiotherapy (nCRT) and surgery for locally advanced esophageal squamous cell carcinoma (ESCC) have a favorable prognosis. However,...

    Ji Yong Kim MD, Jea Kwang Yun MD, PhD, Yong-Hee Kim MD, PhD in Annals of Surgical Oncology (2024)

  17. No Access

    Article

    Feasibility of intraoperative pathologic examination for sentinel lymph nodes during sentinel node navigation surgery in early gastric cancer: results of pathologic protocol for SENORITA trial

    During sentinel node navigation surgery in patients with gastric cancer, intraoperative pathologic examination of sentinel nodes is crucial in determining the extent of surgery. In this study, we evaluated the...

    Sin Hye Park, Soo Young Chung, Jeong-Hee Lee, Hee Kyung Kim, Dakeun Lee in Gastric Cancer (2024)

  18. No Access

    Article

    Prediction of spring steel wire rod hardness based on wire rod rolling process data: a case study

    This study aims to predict the hardness of steel wire rods produced in the actual process by using statistical analysis and machine learning algorithms. The prediction model is built through five steps: operat...

    Seok-Kyu Pyo, Dong-Hee Lee, Sung-Jun Hur in The International Journal of Advanced Manu… (2024)

  19. No Access

    Article

    Transcriptome sequencing of the endangered land snail Karaftohelix adamsi from the Island Ulleung: De novo assembly, annotation, valuation of fitness genes and SSR markers

    The Bradybaenidae snail Karaftohelix adamsi is endemic to Korea, with the species tracked from Island Ulleung in North Gyeongsang Province of South Korea. K. adamsi has been classified under the Endangered Wildli...

    Jie Eun Park, Bharat Bhusan Patnaik, Min Kyu Sang, Dae Kwon Song in Genes & Genomics (2024)

  20. No Access

    Article

    Evaluation of the antinociceptive effect and standardization of Platycladus orientalis (L.) Franco extract

    Platycladus orientalis (L.) Franco (PO) has been used in Oriental medicine to treat rheumatism and diarrhea; however, its antinociceptive effects remain unclear.

    Hyun-Yong Kim, Guanglei Zuo, Hee Jung Lee in Molecular & Cellular Toxicology (2024)

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