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  1. Article

    Correction to: Focused ultrasound combined with radiotherapy for malignant brain tumor: a preclinical and clinical study

    Ko-Ting Chen, Chiung-Yin Huang, **-Ching Pai, Wen-Chi Yang in Journal of Neuro-Oncology (2024)

  2. Article

    Open Access

    Cetuximab Treatment beyond Progression in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Nationwide Population-Based Study (THNS-2021-08)

    Little is known regarding the association of cetuximab treatment beyond progression (TBP) with survival among patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC). Although i...

    Hung-Ming Wang, Pei-Jen Lou, Muh-Hwa Yang, Tein-Hua Chen, Ming-Yu Lien in Targeted Oncology (2024)

  3. No Access

    Article

    Focused ultrasound combined with radiotherapy for malignant brain tumor: a preclinical and clinical study

    Blood–brain barrier (BBB) remains to be the major obstacle to conquer in treating patients with malignant brain tumors. Radiation therapy (RT), despite being the mainstay adjuvant modality regardless of BBB, t...

    Ko-Ting Chen, Chiung-Yin Huang, **-Ching Pai, Wen-Chi Yang in Journal of Neuro-Oncology (2023)

  4. No Access

    Article

    A reconfigurable transistor and memory based on a two-dimensional heterostructure and photoinduced trap**

    Reconfigurable field-effect transistors (FETs) combine unipolar n- and p-type characteristics in a single programmable device and could be used to reduce the complexity of electronic devices. However, current ...

    Meng-Yu Tsai, Chia-Tse Huang, Che-Yi Lin, Mu-Pai Lee, Feng-Shou Yang in Nature Electronics (2023)

  5. Article

    Open Access

    Phylogeny, ancestral ranges and reclassification of sand dollars

    Classification of the Class Echinoidea is under significant revision in light of emerging molecular phylogenetic evidence. In particular, the sister-group relationships within the superorder Luminacea (Echinoi...

    Hsin Lee, Kwen-Shen Lee, Chia-Hsin Hsu, Chen-Wei Lee, Ching-En Li in Scientific Reports (2023)

  6. No Access

    Article

    Prediction of Groundwater Quality Using Seven Types of First-Order Univariate Grey Model in the Chishan Basin, Taiwan

    This study represents the first report of the innovative use of seven types of first-order univariate grey model, abbreviated as GM (1, 1) model, for comprehensive groundwater quality prediction in the Chisha...

    Tzu-Yi Pai, Ray-Shyan Wu, Ching-Ho Chen, Huang-Mu Lo in Water, Air, & Soil Pollution (2022)

  7. Article

    Characterization of congenital factor XII deficiency in Taiwanese patients: identification of one novel and one common mutation

    Factor XII (FXII) deficiency is an interesting condition that causes prolonged activated partial thromboplastin time without bleeding diathesis. FXII may be not important in hemostasis, but still plays roles i...

    Sheng-Chieh Chou, Ching-Yeh Lin, Hsuan-Yu Lin in International Journal of Hematology (2022)

  8. No Access

    Article

    Clinical outcome of local treatment and radical resection for pT1 rectal cancer

    Rectal cancer is mainly cured by radical resection with neoadjuvant chemoradiation or adjuvant chemotherapy. Pathological T1 lesions can be managed by local treatment and radiotherapy thereafter. Lower morbidi...

    Summer Sheue-Tsuey Pai, Hung-Hsin Lin in International Journal of Colorectal Disease (2022)

  9. Article

    Open Access

    Changing surface ocean circulation caused the local demise of echinoid Scaphechinus mirabilis in Taiwan during the Pleistocene–Holocene transition

    Abundant fossil specimens of Scaphechinus mirabilis, now occurring mostly in temperate waters, have been found in the Toukoshan Formation (Pleistocene) in Miaoli County, Taiwan. Environmental changes leading to i...

    Sze Ling Ho, Jia-Kang Wang, Yu-Jou Lin, Ching-Ren Lin, Chen-Wei Lee in Scientific Reports (2022)

  10. Article

    Open Access

    Renal impairment is one of appropriate predictors of future diabetic peripheral neuropathy: a hospital-based 6-year follow-up study

    The relationship between renal impairment and diabetic peripheral neuropathy (DPN) remains inconclusive. We aim to investigate the risk factors for the occurrence of DPN in Taiwanese adults with type 2 diabete...

    Chi-Sheng Wang, Yen-Wei Pai, Ching-Heng Lin, I-Te Lee in Scientific Reports (2022)

  11. Article

    Correction to: Comparative Effectiveness and Tolerability of the Pharmacology of Monoclonal Antibodies Targeting the Calcitonin Gene-Related Peptide and Its Receptor for the Prevention of Chronic Migraine: a Network Meta-analysis of Randomized Controlled Trials

    Chun-Pai Yang, Bing-Yan Zeng, Ching-Mao Chang, Po-Hsuan Shih in Neurotherapeutics (2021)

  12. Article

    Comparative Effectiveness and Tolerability of the Pharmacology of Monoclonal Antibodies Targeting the Calcitonin Gene-Related Peptide and Its Receptor for the Prevention of Chronic Migraine: a Network Meta-analysis of Randomized Controlled Trials

    Monoclonal antibodies (mAbs) acting on the calcitonin gene-related peptide (CGRP) or on its receptor are new therapeutic biologics to prevent chronic migraine (CM). Four mAbs acting on the CGRP or on its recep...

    Chun-Pai Yang, Bing-Yan Zeng, Ching-Mao Chang, Po-Hsuan Shih in Neurotherapeutics (2021)

  13. No Access

    Article

    Detection of Alzheimer’s disease using ECD SPECT images by transfer learning from FDG PET

    To develop a practical method to rapidly utilize a deep learning model to automatically extract image features based on a small number of SPECT brain perfusion images in general clinics to objectively evaluate...

    Yu-Ching Ni, Fan-Pin Tseng, Ming-Chyi Pai, Ing-Tsung Hsiao in Annals of Nuclear Medicine (2021)

  14. No Access

    Article

    Evidence of Potential Mechanisms of Acupuncture from Functional MRI Data for Migraine Prophylaxis

    To summarize the clinical neuroimaging evidence pertaining to the potential mechanisms of acupuncture for migraine prophylaxis.

    Ching-Mao Chang, Chun-Pai Yang, Cheng-Chia Yang in Current Pain and Headache Reports (2021)

  15. Article

    Open Access

    Treatment of intracranial meningioma with single-session and fractionated radiosurgery: a propensity score matching study

    Single-session stereotactic radiosurgery (SSRS) is recognized as a safe and efficient treatment for meningioma. We aim to compare the long-term efficacy and safety of fractionated stereotactic radiotherapy (FS...

    Sheng-Han Huang, Chun-Chieh Wang, Kuo-Chen Wei, Cheng-Nen Chang in Scientific Reports (2020)

  16. Article

    Open Access

    Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis

    The role of fibroblasts in tissue fibrosis has been extensively studied. Activated fibroblasts, namely myofibroblasts, produce pathological extracellular matrix. CD248, a type I transmembrane glycoprotein, is ...

    Chen-Hsueh Pai, Shu-Rung Lin, Chia-Hao Liu, Szu-Yu Pan, Hao Hsu in Scientific Reports (2020)

  17. Article

    Open Access

    Missed radiation therapy sessions in first three weeks predict distant metastasis and less favorable outcomes in surgically treated patients with oral cavity squamous cell carcinoma

    We sought to investigate the prognostic impact of missed RT sessions in patients who had undergone surgery for oral cavity squamous cell carcinoma (OCSCC).

    Yin-Yin Chiang, Yung-Chih Chou, Kai-** Chang, Chun-Ta Liao in Radiation Oncology (2020)

  18. Article

    Open Access

    Oxidation-boosted charge trap** in ultra-sensitive van der Waals materials for artificial synaptic features

    Exploitation of the oxidation behaviour in an environmentally sensitive semiconductor is significant to modulate its electronic properties and develop unique applications. Here, we demonstrate a native oxidati...

    Feng-Shou Yang, Mengjiao Li, Mu-Pai Lee, I-Ying Ho, Jiann-Yeu Chen in Nature Communications (2020)

  19. Article

    Open Access

    Prognostic value of lymph node to primary tumor standardized uptake value ratio in unresectable esophageal cancer

    Unresectable esophageal cancer harbors high mortality despite chemoradiotherapy. Better patient selection for more personalized management may result in better treatment outcomes. We presume the ratio of maxim...

    Po-Jui Chen, Wing-Keen Yap, Yu-Chuan Chang, Chen-Kan Tseng, Yin-Kai Chao in BMC Cancer (2020)

  20. No Access

    Article

    Osteocalcin is an Independent Predictor for Hungry Bone Syndrome After Parathyroidectomy

    Hungry bone syndrome is characterized by prolonged and severe hypocalcemia following parathyroidectomy. Previously, we reported that preoperative alkaline phosphatase is a major factor predicting prolonged hos...

    Wen-Ching Ko, Chien-Liang Liu, Jie-Jen Lee, Tsang-Pai Liu in World Journal of Surgery (2020)

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