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3,429 Result(s)
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Article
Early Therapeutic Drug Monitoring Optimizes Teicoplanin Use in Febrile Neutropenic Patients with Hematological Malignancies
A target trough concentration (Cmin) of teicoplanin ≥ 15–20 mg/L between the fourth and sixth day has been suggested for severe infections or management of febrile neutropenia (FN). Owing to no reports discussing...
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Open AccessDevelo** an entrustable professional activity for providing health education and consultation in occupational therapy and examining its validity
Entrustable Professional Activities (EPA)-based assessment is easily and intuitively used in evaluating the learning outcomes of competency-based medical education (CBME). This study aimed to develop an EPA fo...
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Open AccessPIKfyve, expressed by CD11c-positive cells, controls tumor immunity
Cancer treatment continues to shift from utilizing traditional therapies to targeted ones, such as protein kinase inhibitors and immunotherapy. Mobilizing dendritic cells (DC) and other myeloid cells with anti...
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Open AccessStructural basis for recruitment of peptidoglycan endopeptidase MepS by lipoprotein NlpI
Peptidoglycan (PG) sacculi surround the cytoplasmic membrane, maintaining cell integrity by withstanding internal turgor pressure. During cell growth, PG endopeptidases cleave the crosslinks of the fully close...
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Open AccessGlobal burden, risk factors, and temporal trends of ureteral cancer: a comprehensive analysis of cancer registries
Ureteral cancer is a rare cancer. This study aimed to provide an up-to-date and comprehensive analysis on the global trends of ureteral cancer incidence and its association with lifestyle and metabolic risk fa...
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Open AccessImproved prediction of anti-angiogenic peptides based on machine learning models and comprehensive features from peptide sequences
Angiogenesis is a key process for the proliferation and metastatic spread of cancer cells. Anti-angiogenic peptides (AAPs), with the capability of inhibiting angiogenesis, are promising candidates in cancer tr...
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Strategic legislation for the promotion of university–industry collaborations: a case study of Taiwan
The strategic utilization of technology to enhance industrial competitiveness and product quality is pivotal for economic growth. As universities own more inventions, collaborative efforts between industry and...
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German and Taiwanese secondary students’ mathematical modelling task value profiles and their relation to mathematical knowledge and modelling performance
Based on expectancy-value theory, this study adopted a person-centred approach to explore the heterogeneous profiles of secondary German and Taiwanese students’ mathematical modelling task values, and examined...
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Open AccessUse of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 Å
While cryogenic electron microscopy (cryo-EM) is fruitfully used for harvesting high-resolution structures of sizable macromolecules, its application to small or flexible proteins composed of small domains lik...
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Open AccessHigh prevalence of exon-13 variants in USH2A-related retinal dystrophies in Taiwanese population
Biallelic pathogenic variants in USH2A lead to Usher syndrome or non-syndromic retinitis pigmentosa, and shown to have geographical and ethnical distribution in previous studies. This study provided a deeper unde...
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Can weekend catch-up sleep decrease the risk of cognitive dysfunction in older adults?
This study investigated whether weekend catch-up sleep was related to a decreased risk of cognitive dysfunction in older Taiwanese adults by using self-reported diaries and objective accelerometer measurements.
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An Automatic Approach of Video-Based Landmark Detection and Movement Analysis for Assessing Symptoms of Bradykinesia in Parkinson’s Disease
Parkinson’s disease (PD) is a complex neurodegenerative disorder characterized by diverse symptoms. Diagnosis relies on established criteria and comprehensive assessment. The Movement Disorder Society Unified ...
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Open AccessStudy on different isolation technology on the performance of blue micro-LEDs array applications
In this study, a 3 × 3 blue micro-LED array with a pixel size of 10 × 10 μm2 and a pitch of 15 μm was fabricated on an epilayer grown on a sapphire substrate using metalorganic chemical vapor deposition technolog...
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Open AccessEmission characterizations and environmental impacts of off-road vehicles
This study measured particulate matter (PM) and gaseous pollutants in the exhaust of off-road vehicles (excavators, bulldozers) during idling and working. The fingerprint of metals in PM and the emission facto...
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Integrating online partial pair programming and socially shared metacognitive regulation for the improvement of students’ learning
Many universities around the world were forced to lock down and students had to continue their learning in online environments in response to the COVID-19 pandemic. Teachers thus had to adopt effective and app...
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Reply to: Critical comment on the assumptions leading to 24-chain microfibrils in wood
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Industry perspective on power electronics for electric vehicles
Driven by the global effort towards reduction of carbon dioxide emissions from cars, the gradual phase out of fuel cars accompanied by the rise of electric vehicles (EVs) has become a megatrend. Despite the ra...
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Open AccessBeyond prevalence: significance and differential impact of echocardiographic abnormalities in dialysis patients
Echocardiography is commonly used to assess hydratation status and cardiac function in kidney failure patients, but the impact of structural or functional abnormalities on the prognosis of kidney failure patie...
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Open AccessBurnout during the COVID-19 pandemic among nurses in Taiwan: the parental role effect on burnout
During the COVID-19 pandemic, medical workers were concerned about the care of their children or family members and the impact of being separated from them. This increased stress could harm the relationship be...
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Open AccessAssociation between statin therapy and long-term clinical outcomes in patients with stable coronary disease undergoing percutaneous coronary intervention
This longitudinal cohort study examined the long-term effect of statin therapy on clinical outcomes in patients undergoing percutaneous coronary intervention (PCI). A total of 1760 patients with stable coronar...