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  1. No Access

    Article

    Early Therapeutic Drug Monitoring Optimizes Teicoplanin Use in Febrile Neutropenic Patients with Hematological Malignancies

    A target trough concentration (Cmin) of teicoplanin ≥ 15–20 mg/L between the fourth and sixth day has been suggested for severe infections or management of febrile neutropenia (FN). Owing to no reports discussing...

    Yu-Wen Wang, Hsin-An Hou, Chien-Chin Lin, Hsing-Yu Lin, Pin-Zi Chen in Advances in Therapy (2024)

  2. Article

    Open Access

    Develo** an entrustable professional activity for providing health education and consultation in occupational therapy and examining its validity

    Entrustable Professional Activities (EPA)-based assessment is easily and intuitively used in evaluating the learning outcomes of competency-based medical education (CBME). This study aimed to develop an EPA fo...

    Chung-Pei Fu, Ching-Kai Huang, Yi-Chiun Yang, Wei-Sheng Liao in BMC Medical Education (2024)

  3. Article

    Open Access

    PIKfyve, expressed by CD11c-positive cells, controls tumor immunity

    Cancer treatment continues to shift from utilizing traditional therapies to targeted ones, such as protein kinase inhibitors and immunotherapy. Mobilizing dendritic cells (DC) and other myeloid cells with anti...

    Jae Eun Choi, Yuanyuan Qiao, Ilona Kryczek, Jiali Yu in Nature Communications (2024)

  4. Article

    Open Access

    Structural basis for recruitment of peptidoglycan endopeptidase MepS by lipoprotein NlpI

    Peptidoglycan (PG) sacculi surround the cytoplasmic membrane, maintaining cell integrity by withstanding internal turgor pressure. During cell growth, PG endopeptidases cleave the crosslinks of the fully close...

    Shen Wang, Chun-Hsiang Huang, Te-Sheng Lin, Yi-Qi Yeh in Nature Communications (2024)

  5. Article

    Open Access

    Global burden, risk factors, and temporal trends of ureteral cancer: a comprehensive analysis of cancer registries

    Ureteral cancer is a rare cancer. This study aimed to provide an up-to-date and comprehensive analysis on the global trends of ureteral cancer incidence and its association with lifestyle and metabolic risk fa...

    Junjie Huang, Wing Sze Pang, Yat Ching Fung, Fung Yu Mak, Sze Chai Chan in BMC Medicine (2024)

  6. Article

    Open Access

    Improved prediction of anti-angiogenic peptides based on machine learning models and comprehensive features from peptide sequences

    Angiogenesis is a key process for the proliferation and metastatic spread of cancer cells. Anti-angiogenic peptides (AAPs), with the capability of inhibiting angiogenesis, are promising candidates in cancer tr...

    Yun-Chen Lee, Jen-Chieh Yu, Kuan Ni, Yu-Chuan Lin, Ching-Tai Chen in Scientific Reports (2024)

  7. No Access

    Article

    Strategic legislation for the promotion of university–industry collaborations: a case study of Taiwan

    The strategic utilization of technology to enhance industrial competitiveness and product quality is pivotal for economic growth. As universities own more inventions, collaborative efforts between industry and...

    Thanh Hue Truong, Bou-Wen Lin, Ching-Pin Tung in The Journal of Technology Transfer (2024)

  8. No Access

    Article

    German and Taiwanese secondary students’ mathematical modelling task value profiles and their relation to mathematical knowledge and modelling performance

    Based on expectancy-value theory, this study adopted a person-centred approach to explore the heterogeneous profiles of secondary German and Taiwanese students’ mathematical modelling task values, and examined...

    Kai-Lin Yang, Janina Krawitz in European Journal of Psychology of Education (2024)

  9. Article

    Open Access

    Use of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 Å

    While cryogenic electron microscopy (cryo-EM) is fruitfully used for harvesting high-resolution structures of sizable macromolecules, its application to small or flexible proteins composed of small domains lik...

    Hsin-Hung Lin, Chun-Hsiung Wang, Shih-Hsin Huang, Sung-Yao Lin in Scientific Reports (2024)

  10. Article

    Open Access

    High prevalence of exon-13 variants in USH2A-related retinal dystrophies in Taiwanese population

    Biallelic pathogenic variants in USH2A lead to Usher syndrome or non-syndromic retinitis pigmentosa, and shown to have geographical and ethnical distribution in previous studies. This study provided a deeper unde...

    Yu-Wei Lin, Yu-Shu Huang, Chien-Yu Lin, Chao-Wen Lin in Orphanet Journal of Rare Diseases (2024)

  11. No Access

    Article

    Can weekend catch-up sleep decrease the risk of cognitive dysfunction in older adults?

    This study investigated whether weekend catch-up sleep was related to a decreased risk of cognitive dysfunction in older Taiwanese adults by using self-reported diaries and objective accelerometer measurements.

    Chi Hsiao, Wan-Chi Huang, Ming-Chun Hsueh, Chih-Ching Chang in Sleep and Breathing (2024)

  12. No Access

    Article

    An Automatic Approach of Video-Based Landmark Detection and Movement Analysis for Assessing Symptoms of Bradykinesia in Parkinson’s Disease

    Parkinson’s disease (PD) is a complex neurodegenerative disorder characterized by diverse symptoms. Diagnosis relies on established criteria and comprehensive assessment. The Movement Disorder Society Unified ...

    Ching-Fang Chien, Chen-Sen Ouyang in Journal of Medical and Biological Engineer… (2024)

  13. Article

    Open Access

    Study on different isolation technology on the performance of blue micro-LEDs array applications

    In this study, a 3 × 3 blue micro-LED array with a pixel size of 10 × 10 μm2 and a pitch of 15 μm was fabricated on an epilayer grown on a sapphire substrate using metalorganic chemical vapor deposition technolog...

    Shao-Hua Lin, Yu-Yun Lo, Yu-Hsuan Hsu, Chien-Chung Lin, Hsiao-Wen Zan in Discover Nano (2024)

  14. Article

    Open Access

    Emission characterizations and environmental impacts of off-road vehicles

    This study measured particulate matter (PM) and gaseous pollutants in the exhaust of off-road vehicles (excavators, bulldozers) during idling and working. The fingerprint of metals in PM and the emission facto...

    Hsing-Wang Li, Chia-Hsiang Lai, Ku-Fan Chen in Sustainable Environment Research (2024)

  15. No Access

    Article

    Integrating online partial pair programming and socially shared metacognitive regulation for the improvement of students’ learning

    Many universities around the world were forced to lock down and students had to continue their learning in online environments in response to the COVID-19 pandemic. Teachers thus had to adopt effective and app...

    Chia-Wen Tsai, Michael Yu-Ching Lin in Universal Access in the Information Society (2024)

  16. No Access

    Article

    Reply to: Critical comment on the assumptions leading to 24-chain microfibrils in wood

    Hwan-Ching Tai, Cheng-Si Tsao, Jer-Horng Lin in Nature Plants (2024)

  17. No Access

    Article

    Industry perspective on power electronics for electric vehicles

    Driven by the global effort towards reduction of carbon dioxide emissions from cars, the gradual phase out of fuel cars accompanied by the rise of electric vehicles (EVs) has become a megatrend. Despite the ra...

    Chang-Ching Tu, Chia-Lung Hung, Kuo-Bin Hong in Nature Reviews Electrical Engineering (2024)

  18. Article

    Open Access

    Beyond prevalence: significance and differential impact of echocardiographic abnormalities in dialysis patients

    Echocardiography is commonly used to assess hydratation status and cardiac function in kidney failure patients, but the impact of structural or functional abnormalities on the prognosis of kidney failure patie...

    Chih-Hsueh Tseng, Yi-An Hu, Yung-Tai Chen, Wen-Chung Yu in Journal of Nephrology (2024)

  19. Article

    Open Access

    Burnout during the COVID-19 pandemic among nurses in Taiwan: the parental role effect on burnout

    During the COVID-19 pandemic, medical workers were concerned about the care of their children or family members and the impact of being separated from them. This increased stress could harm the relationship be...

    Yong-Hsin Chen, Mohsen Saffari, Chung-Ying Lin in BMC Health Services Research (2024)

  20. Article

    Open Access

    Association between statin therapy and long-term clinical outcomes in patients with stable coronary disease undergoing percutaneous coronary intervention

    This longitudinal cohort study examined the long-term effect of statin therapy on clinical outcomes in patients undergoing percutaneous coronary intervention (PCI). A total of 1760 patients with stable coronar...

    Han-** Wu, Feng-Ching Yang, Hau-De Lin, Chuan-Zhong Cai in Scientific Reports (2024)

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