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    Article

    Correlative metabologenomics of 110 fungi reveals metabolite–gene cluster pairs

    Natural products research increasingly applies -omics technologies to guide molecular discovery. While the combined analysis of genomic and metabolomic datasets has proved valuable for identifying natural prod...

    Lindsay K. Caesar, Fatma A. Butun, Matthew T. Robey… in Nature Chemical Biology (2023)

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    Article

    A scalable platform to identify fungal secondary metabolites and their gene clusters

    Coupling the use of artificial chromosomes with metabolomics enables the high-throughput linkage of fungal natural products with their biosynthetic gene clusters. This method was used here to identify a novel...

    Kenneth D Clevenger, ** Woo Bok, Rosa Ye, Galen P Miley… in Nature Chemical Biology (2017)

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    Article

    Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus

    Analysis of orphan nonribosomal peptide synthetase–like gene clusters from Aspergillus fumigatus identified a gene cluster responsible for the biosynthesis of fumisoquin isoquinoline alkaloids by amino acid conde...

    Joshua A Baccile, Joseph E Spraker, Henry H Le… in Nature Chemical Biology (2016)

  4. Article

    Correction: Corrigendum: Chromatin-level regulation of biosynthetic gene clusters

    Nat. Chem. Biol. 5, 462–464 (2009); published online 17 May 2009; corrected after print 18 August 2009 In the version of this article initially published, the fourth author's last name is misspelled. The autho...

    ** Woo Bok, Yi-Ming Chiang, Edyta Szewczyk… in Nature Chemical Biology (2009)

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    Article

    Chromatin-level regulation of biosynthetic gene clusters

    ** Woo Bok, Yi-Ming Chiang, Edyta Szewczyk… in Nature Chemical Biology (2009)