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    Article

    Vascular endothelial growth factor enhances axonal outgrowth in organotypic spinal cord slices via vascular endothelial growth factor receptor 1 and 2

    Enhancing adult nerve regeneration is a potential therapeutic strategy for treating spinal cord injury. Vascular endothelial growth factor (VEGF) is a major contributor to angiogenesis, which can reduce the sp...

    Hwan-Woo Park, Hyo-** Jeon, Mi-Sook Chang in Tissue Engineering and Regenerative Medicine (2016)

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    Article

    Ankyrin repeat-rich membrane spanning/Kidins220 protein interacts with mammalian Septin 5

    Neurotrophin receptors utilize specific adaptor proteins to activate signaling pathways involved in various neuronal functions, such as neurite outgrowth and cytoskeletal remodeling. The Ankyrin-Repeat Rich Me...

    Han Jeong Park, Hwan-Woo Park, Shin-Jae Lee, Juan Carlos Arevalo in Molecules and Cells (2010)

  3. Article

    Open Access

    A versatile approach to multiple gene RNA interference using microRNA-based short hairpin RNAs

    Effective and stable knockdown of multiple gene targets by RNA interference is often necessary to overcome isoform redundancy, but it remains a technical challenge when working with intractable cell systems.

    **aocui Zhu, Leah A Santat, Mi Sook Chang, Jamie Liu in BMC Molecular Biology (2007)

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    Article

    Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

    RNA interference (RNAi) is the process of sequence-specific post-transcriptional gene silencing triggered by double-stranded RNAs1,2,3. In attempts to identify RNAi triggers that effectively function at lower con...

    Dong-Ho Kim, Mark A Behlke, Scott D Rose, Mi-Sook Chang in Nature Biotechnology (2005)

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    Chapter

    Enhancing RNAi with Synthetic RNA Duplexes

    Dong-Ho Kim, Mark A. Behlke, Scott D. Rose, Mi-Sook Chang in Non-viral Gene Therapy (2005)

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    Article

    The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC–Cdc20 complex

    The tumour suppressor gene RASSF1A is frequently silenced in lung cancer and other sporadic tumours as a result of hypermethylation of a CpG island in its promoter1,2,3,4,5,6. However, the precise mechanism by wh...

    Min Sup Song, Su Jeong Song, Nagi G. Ayad, ** Sook Chang in Nature Cell Biology (2004)