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  1. Article

    Open Access

    Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics

    Preclinical studies have evaluated haptoglobin (Hp) polymers from pooled human plasma as a therapeutic protein to attenuate toxic effects of cell-free hemoglobin (Hb). Proof of concept studies have demonstrate...

    Christian A. Schaer, Catherine Owczarek, Jeremy W. Deuel in BMC Biotechnology (2018)