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High-aspect-ratio three-dimensional polymer and metallic microstructure microfabrication using two-photon polymerization
Creating micrometer-resolution high-aspect-ratio three-dimensional (3D) structures remain very challenging despite significant microfabrication...
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A 3D printed acoustofluidic nozzle-diffuser microfluidic pump
Microfluidic flow control systems are critical components for on-chip biomedical applications. This study introduces a new micropump for on-chip...
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3D printing redefines microneedle fabrication for transdermal drug delivery
Microneedles (MNs) have emerged as an innovative, virtually painless technique for intradermal drug delivery. However, the complex and costly...
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Microfluidic high-throughput 3D cell culture
High-throughput 3D microfluidic cell culture systems can be designed to model aspects of human tissues and organs and may thus serve as non-clinical...
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3D passive microfluidic valves in silicon and glass using grayscale lithography and reactive ion etching transfer
A fabrication strategy for high-efficiency passive three-dimensional microfluidic valves with no mechanical parts fabricated in silicon and glass...
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Quantitative Determination of 3D-Printing and Surface-Treatment Conditions for Direct-Printed Microfluidic Devices
We report a quantitative and systematic method for determining 3D-printing and surface-treatment conditions that can help improve the optical quality...
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Embedded macrophages induce intravascular coagulation in 3D blood vessel-on-chip
Macrophages are innate immune cells that prevent infections and help in wound healing and vascular inflammation. While these cells are natural helper...
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Microfabrication of a biomimetic arcade-like electrospun scaffold for cartilage tissue engineering applications
In recent years, the engineering of biomimetic cellular microenvironments has emerged as a top priority for regenerative medicine, being the in vitro...
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Acoustic prison for single live cell 3D multi-imaging enabled by light-sheet microscopy
Having a system capable of obtaining high resolution, quantitative, subcellular information of individual live cells through imaging, while...
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Polysaccharide-Based Hydrogels for Bioengineering 3D Tumor Models
Cancer is the leading cause of death worldwide and its incidence is expected to rise. Despite overwhelming efforts to design innovative preclinical...
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Cancer-on-chip: a 3D model for the study of the tumor microenvironment
The approval of anticancer therapeutic strategies is still slowed down by the lack of models able to faithfully reproduce in vivo cancer physiology....
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Fabrication of Brain-on-a-Chip Devices
This chapter reviews the current common techniques for the biofabrication of brain-on-a-chip devices. These devices have extensive applicability in...
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Engineering biomimetic intestinal topological features in 3D tissue models: retrospects and prospects
Conventional 2D intestinal models cannot precisely recapitulate biomimetic features in vitro and thus are unsuitable for various pharmacokinetic...
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Engineering Distance Learning: The Promise and Challenges of Microfluidics
The recent trend of expanding online education in science and engineering creates the need for remote experiential learning opportunities....
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3D Microwell Platforms for Control of Single Cell 3D Geometry and Intracellular Organization
IntroductionCell structure and migration is impacted by the mechanical properties and geometry of the cell adhesive environment. Most studies to date...
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Microfabricated Systems for Cardiovascular Tissue Modeling
This chapter provides a brief review of different microfabricated platforms for in vitro modeling of cardiac tissue. The initial focus is on the...
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3D Artificial Cell Membranes as Versatile Platforms for Biological Applications
Artificial cell membranes, emulating biological membranes, have been used to elucidate the physiological functions of cells and realize biological...
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High-throughput microbead assay system with a portable, cost-effective Wi-Fi imaging module, and disposable multi-layered microfluidic cartridges for virus and microparticle detection, and tracking
In recent years biomedical scientific community has been working towards the development of high-throughput devices that allow a reliable, rapid and...
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A 3D hydrodynamic flow-focusing device for cell sorting
Optical-based microfluidic cell sorting has become increasingly attractive for applications in life and environmental sciences due to its ability of...
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3D Printing for Cardiovascular Applications: From End-to-End Processes to Emerging Developments
3D printing as a means of fabrication has seen increasing applications in medicine in the last decade, becoming invaluable for cardiovascular...
