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    Pathologic Perspectives on Prognosis in Soft Tissue Sarcoma

    Sarcomas, a diverse group of malignant neoplasms originating from connective tissues, include over 70 recognized subtypes. Although sarcomas constitute a smaller proportion of cancers in adults, they are notab...

    Armita Bahrami in Pediatric Surgical Oncology

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    The Surgeon and the Decision-Making Process for Children with Cancer

    Surgery plays critical roles in pediatric cancer care and pediatric oncology surgeons are key to the successful treatment of children with cancer in various ways. This chapter invites you to travel through the...

    Simone de Campos Vieira Abib in Pediatric Surgical Oncology

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    Principles of Intervention

    Surgical intervention plays a major part in the management of many pediatric cancer patients. The particular role it plays varies with the diagnosis and location of the disease. The goals of surgical intervent...

    Merrill McHoney in Pediatric Surgical Oncology

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    Hereditary Factors in Carcinogenesis and the Key Cancer Syndromes

    Cancer is a genetic disease—with the role of somatic mutations in tumor cells well-described in all cancer types. The role of germline genetic changes has also been long-recognized in familial cancer syndromes...

    Anna M. Rose, Amy F. Mitchell in Pediatric Surgical Oncology

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    Infections in Immunosuppressed Pediatric Patients

    Infections are an important cause of morbidity and mortality in children undergoing treatment for cancer. Up to two-thirds of toxic deaths during cancer treatment are caused by infections, which are especially...

    Joanna Jennia Acebo, Parthasarathi Bhattacharyya in Pediatric Surgical Oncology

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    Testicular Torsion

    Testicular torsion is the most common genitourinary emergency in childhood with an estimated incidence of 3.5–4.5 per 100.000 males younger than 25 years attending the hospital every year (Mansbach et al., Arc...

    Salvatore Cascio in Pediatric Surgery (2023)

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    Augmentation Cystoplasty

    Bladder augmentation (BA) with GI tissue is an important tool in the armamentarium of the urologist in the management of children requiring reconstruction for urinary incontinence, preserving the upper urinary...

    Boris Chertin, Stanislav Koucherov, Ofer Z. Shenfeld in Pediatric Surgery (2023)

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    Childhood Outcome Disparities in Cancer Care

    The limited data on childhood cancer incidence in low- and middle-income countries (LMICs), evidenced from the few cancer registries from such countries that contributed data to IICC-3 and other similar projec...

    Lorna A. Renner in Pediatric Surgical Oncology

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    Embryology of the Urinary Tract

    Embryology provides the basis for the understanding of human anatomy – as a field, it has expanded exponentially following advances in molecular and experimental techniques. An understanding of embryogenesis a...

    K. L. M. Pfistermüller, Peter Cuckow in Pediatric Surgery (2023)

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    Adverse Effects and Considerations Associated with Excessive or Unwarranted Imaging

    Medical imaging plays a crucial role in the diagnosis, staging, monitoring of response to therapy and longitudinally following patients after completion of therapy to detect recurrent disease, second cancers, ...

    Sue C. Kaste in Pediatric Surgical Oncology

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    Emergency in Pediatric Oncology

    Emergencies in pediatric oncology are extreme situations where the oncologist and surgeon have to be quick and accurate in solving the problem. Working with a trained and coordinated multiprofessional team is ...

    Rodrigo Chaves Ribeiro in Pediatric Surgical Oncology

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    Ureteropelvic Junction Obstruction

    With the wide spread of maternal ultrasound, the incidence of hydronephrosis has increased significantly, altering the practice of urology. Management of antenatal hydronephrosis after birth remains controvers...

    Boris Chertin, Galiya Raisin, Prem Puri in Pediatric Surgery

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    Ureteral Duplication and Duplex Systems

    There is a huge anatomical variety in ureteral duplications, ureteral ectopia, and ureteroceles. Embryology is complex and often not well understood. Due to the heterogeneity of patients with those issues, the...

    Ramnath Subramaniam, Alexander Springer in Pediatric Surgery (2023)

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    Evaluation and Management of Urinary Tract Infections in Children

    Urinary tract infections (UTI) represent a major infectious etiology of morbidity in children. Over the past two decades, the approach to evaluation and management of factors associated with the pathogenesis o...

    Linda C. Lee, Frank J. Penna, Martin A. Koyle in Pediatric Surgery (2023)

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    Indications for Gene Testing for At Risk Families and Genetic Risk Calculation

    Approximately 10–15% of pediatric malignancies can be attributed to an underlying cancer predisposition syndrome (CPS). Heritable conditions arise in the germline as a result of a pathogenic variant (mutation)...

    Kanika Bhatia, Nisreen Amayiri in Pediatric Surgical Oncology

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    Magnetic Resonance Imaging of the Urinary Tract

    Magnetic resonance imaging (MRI) is evolving as an imaging modality for the urinary tract that offers not only superior anatomic but also functional assessment, without the use of ionizing radiation. This comp...

    Kristin M. Broderick, J. Damien Grattan-Smith, Andrew J. Kirsch in Pediatric Surgery (2023)

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    Dialysis

    Providing optimum care to the infant, child, and adolescent patient requiring acute or chronic dialysis therapy demands that attention be directed to a variety of clinical issues. Pediatric patients with acute...

    Dieter Haffner, Christian Lerch in Pediatric Surgery (2023)

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    Novel Imaging Techniques for Childhood Cancer Management

    Imaging in pediatric oncology is taking on increasing roles in diagnosis, staging, treatment planning, and monitoring of response to therapy. Novel techniques, sparked by advances in hardware and software tech...

    Zachary Abramson, Amy Vavere, Matthew Scoggins in Pediatric Surgical Oncology

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    Nutrition Supportive Care of the Pediatric Oncology Patient Undergoing Surgery

    Managing the medical nutrition therapy of children undergoing treatment for cancer can be daunting. During cancer treatment there are many side effects that may hinder the provision of adequate nutrients for p...

    Karen Ringwald-Smith, Carla Cartwright, Madison Tyler in Pediatric Surgical Oncology

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    Principles of Minimally Invasive Surgery

    Minimally invasive surgical techniques have become utilized to perform increasingly complex procedures. Initially used in adults, technology and experience have allowed surgeons and urologists to limit the nee...

    Joseph J. Pariser, Blake B. Anderson, Mohan S. Gundeti in Pediatric Surgery (2023)

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