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    Characterization of Smoothened Phosphorylation and Activation

    The GPCR-family protein Smoothened (Smo) is an obligatory signal transducer of the Hedgehog (Hh) signaling pathway. Binding of Hh to its receptor Patched (Ptc) alleviates Ptc-mediated inhibition of Smo, allowi...

    Jianhang Jia, Yuhong Han, Yong Suk Cho, ** Jiang in Hedgehog Signaling (2022)