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    p53 Ubiquitination and Proteasomal Degradation

    p53 levels and activity are controlled in large part through regulated ubiquitination and subsequent destruction by the 26S proteasome. Monoubiquitination of p53 is mediated primarily by the RING-finger E3 ubi...

    Ian M. Love, Dingding Shi, Steven R. Grossman in p53 Protocols (2013)