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Protocol
In Vitro Preparation and Crystallization of Vertebrate Telomerase Subunits
Telomerase is a unique reverse transcriptase that replicates the telomeric DNA at most eukaryotic chromosomal ends. The telomerase consists of the catalytic protein subunit TERT and the RNA component TR that p...
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Protocol
Human Telomere POT1-TPP1 Complex and Its Role in Telomerase Activity Regulation
Telomeres, the specialized DNA-protein complexes found at the termini of all linear eukaryotic chromosomes, protect chromosomes from degradation and end-to-end fusion. The protection of telomeres 1 (POT1) pro...