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within Biomedicine Remove this filter Medicinal Chemistry Remove this filter Pharmacology/Toxicology Remove this filter Ke** Zhang Remove this filter Protocol Remove this filter

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    Protocol

    A Combinatorial Strategy for the Acquisition of Potent and Specific Protein Tyrosine Phosphatase Inhibitors

    Protein tyrosine phosphatases (PTPs), a large family of signaling enzymes, regulate many cellular processes, such as proliferation, differentiation, migration, apoptosis, and immune responses. Small molecule i...

    Sheng Zhang, Lan Chen, David S. Lawrence, Zhong-Yin Zhang in Rational Drug Design (2012)

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    Protocol

    Mouse Models for Tumor Metastasis

    Tumor metastasis is the main cause of death of cancer patients. Here we describe two mouse models for investigating tumor metastasis. In the first spontaneous metastasis mouse model, 4T1 mouse breast tumor cel...

    Shengyu Yang, J. Jillian Zhang, **n-Yun Huang in Rational Drug Design (2012)