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  1. No Access

    Protocol

    Targeting Cancer Cell Death with Small Molecule Agents for Potential Therapeutics

    Time has come to switch from morphological to molecular definitions of cell death subroutines, due to substantial progress in biochemical and genetic exploration. Currently, cell death subroutines are defined ...

    Lan Zhang, Yaxin Zheng, Mao Tian, Shouyue Zhang, Bo Liu… in Apoptosis Methods in Toxicology (2016)

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    Protocol

    Microplate-Based Whole Zebrafish Caspase 3/7 Assay for Screening Small Molecule Compounds

    In this research, using a commercially available human specific caspase 3/7 chemiluminescent test kit (Caspase 3/7 Glo, Promega, Madison, WI), developed for cell based assays, we describe a microplate-based wh...

    Wen Lin Seng, Dawei Zhang, Patricia McGrath in Apoptosis Methods in Toxicology (2016)

  3. No Access

    Protocol

    Detection of Apoptosis: From Bench Side to Clinical Practice

    Apoptosis or programmed cell death is implicated in several pathological conditions, such as cancer and neurodegenerative diseases. An increasing number of therapies are developed by targeting apoptosis signal...

    William P. Bozza, Julianne D. Twomey, Su-Ryun Kim… in Apoptosis Methods in Toxicology (2016)