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Protocol
Targeting Cancer Cell Death with Small Molecule Agents for Potential Therapeutics
Time has come to switch from morphological to molecular definitions of cell death subroutines, due to substantial progress in biochemical and genetic exploration. Currently, cell death subroutines are defined ...
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Protocol
Microplate-Based Whole Zebrafish Caspase 3/7 Assay for Screening Small Molecule Compounds
In this research, using a commercially available human specific caspase 3/7 chemiluminescent test kit (Caspase 3/7 Glo, Promega, Madison, WI), developed for cell based assays, we describe a microplate-based wh...
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Protocol
Detection of Apoptosis: From Bench Side to Clinical Practice
Apoptosis or programmed cell death is implicated in several pathological conditions, such as cancer and neurodegenerative diseases. An increasing number of therapies are developed by targeting apoptosis signal...